Patents by Inventor Niels Ramsing
Niels Ramsing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11124764Abstract: Apparatus and methods for monitoring embryos in an incubator are described. The apparatus comprises an incubation chamber defined by an incubation chamber housing and a sample platform comprising a plurality of receptacles for holding embryos within the incubation chamber for incubation. The sample platform may comprise a slide carrier on which embryo slides containing the receptacles may be placed incubation. The sample platform is rotatable about a rotation axis relative to the incubation chamber housing so as to allow receptacles to be selectively rotated to a monitoring position that is aligned with a viewing port provided in the incubation chamber housing, for example an opening or window. An imaging device is located outside the incubation chamber and arranged to image embryos within the incubation chamber at the monitoring position through the viewing port.Type: GrantFiled: January 13, 2015Date of Patent: September 21, 2021Assignee: UNISENSE FERTILITECH A/SInventors: Niels Ramsing, Jonas Lerche Hansen, Kim Bondergaard Madsen, Troels Kofoed Mejer, Jorgen Berntsen
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Patent number: 10844342Abstract: Apparatus and methods for monitoring embryos in an incubator are described. The apparatus comprises an incubation chamber defined by an incubation chamber housing and a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation. The slide carrier is moveable, for example by rotation, relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing. The loading port wall is arranged to cooperate with the wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber.Type: GrantFiled: January 13, 2015Date of Patent: November 24, 2020Assignee: UNISENSE FERTILITECH A/SInventors: Niels Ramsing, Kim Bondergaard Madsen, Jonas Lerche Hansen, Troels Kofoed Mejer, Jorgen Berntsen
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Patent number: 10282842Abstract: Apparatus and methods for helping a user establish values (e.g. timings) for a plurality of parameters of interest (e.g. cell divisions) relating to the development of an embryo from a series of images of the embryo are described. For each parameter of interest an image is selected for display to a user seeking to establish a value for the parameter of interest. For example, the selected image may be an image predicted to be an image reflecting the value for the parameter of interest. For example, the selected image may be based on a calculated timing for a particular developmental event. The timing may be calculated from a numerical analysis of the images or maybe predetermined. If the user is unable to determine a value for the parameter of interest from the selected image, the user may scroll through neighboring images until the user can determine a value for the parameter of interest.Type: GrantFiled: February 12, 2015Date of Patent: May 7, 2019Assignee: UNISENSE FERTILITECH A/SInventors: Anton Paarup Kylling, Jorgen Berntsen, Niels Ramsing, Soren Porsgaard, Tine Qvistgaard Kajhoj, Reidun Berghold Kuhlmann
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Publication number: 20170044476Abstract: A culture dish for holding one or more object to be cultured is described. The culture dish has a main body comprising at least one well for receiving an object to be cultured and a quantity of culturing media for the object, such as a water-based growth media, and a reservoir for receiving a quantity of cover media, such as mineral oil. The at least one well is provided in a floor of the reservoir so that when in normal use cover media in the reservoir overlays culturing media in the at least one well. The reservoir is defined by the reservoir floor and a reservoir wall extending away from the reservoir floor. At least a section of the reservoir wall is angled away from the vertical so as to be inclined with respect to a horizontal plane defined by a surface of cover media in the reservoir when the culture dish is in normal use.Type: ApplicationFiled: March 24, 2015Publication date: February 16, 2017Applicant: Unisense FertiliTech A/SInventors: Kim Bondergaard Madsen, Jonas Lerche Hansen, Soren Porsgaard, Niels Ramsing, Jorgen Bertsen
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Publication number: 20170009202Abstract: Apparatus and methods for monitoring embryos in an incubator are described. The apparatus comprises an incubation chamber defined by an incubation chamber housing and a sample platform comprising a plurality of receptacles for holding embryos within the incubation chamber for incubation. The sample platform may comprise a slide carrier on which embryo slides containing the receptacles may be placed incubation. The sample platform is rotatable about a rotation axis relative to the incubation chamber housing so as to allow receptacles to be selectively rotated to a monitoring position that is aligned with a viewing port provided in the incubation chamber housing, for example an opening or window. An imaging device is located outside the incubation chamber and arranged to image embryos within the incubation chamber at the monitoring position through the viewing port.Type: ApplicationFiled: January 13, 2015Publication date: January 12, 2017Applicant: UNISENSE FERTILITECH A/SInventors: Niels Ramsing, Jonas Lerche Hansen, Kim Bondergaard Madsen, Troels Kofoed Mejer, Jorgen Berntsen
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Publication number: 20170009195Abstract: Apparatus and methods for monitoring embryos in an incubator are described. The apparatus comprises an incubation chamber defined by an incubation chamber housing and a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation. The slide carrier is moveable, for example by rotation, relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing. The loading port wall is arranged to cooperate with the wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber.Type: ApplicationFiled: January 13, 2015Publication date: January 12, 2017Applicant: UNISENSE FERTILITECH A/SInventors: Niels Ramsing, Kim Bondergaard Madsen, Jonas Lerche Hansen, Troels Kofoed Mejer, Jorgen Berntsen
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Publication number: 20160379364Abstract: Apparatus and methods for helping a user establish values (e.g. timings) for a plurality of parameters of interest (e.g. cell divisions) relating to the development of an embryo from a series of images of the embryo are described. For each parameter of interest an image is selected for display to a user seeking to establish a value for the parameter of interest. For example, the selected image may be an image predicted to be an image reflecting the value for the parameter of interest. For example, the selected image may be based on a calculated timing for a particular developmental event. The timing may be calculated from a numerical analysis of the images or maybe predetermined. If the user is unable to determine a value for the parameter of interest from the selected image, the user may scroll through neighbouring images until the user can determine a value for the parameter of interest.Type: ApplicationFiled: February 12, 2015Publication date: December 29, 2016Applicant: Unisense FertiliTech A/SInventors: Anton Paarup Kylling, Jorgen Berntsen, Niels Ramsing, Soren Porsgaard, Tine Qvistgaard Kajhoj, Reidun Berghold Kuhlmann
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Publication number: 20060166238Abstract: The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantifying components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.Type: ApplicationFiled: December 21, 2005Publication date: July 27, 2006Inventors: Niels Ramsing, Peter Mouritzen, Soren Echwald, Niels Tolstrup
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Publication number: 20060099570Abstract: The present invention relates to methods and devices for non-invasive and non-disturbing measurements of metabolizing rates of substantially spherical metabolizing particles, such as an embryo, and to a method and device for controlling oxygen partial pressure at the level of the embryo. Furthermore, the invention relates to a method for regulating supply of metabolites to a substantially spherical metabolizing particle, as well as a method for selecting substantially spherical metabolizing particles of a predetermined quality. The invention is carried out in a device capable of establishing a diffusion gradient of metabolites between the substantially spherical metabolizing particle inside a compartment in the device and the environment outside the compartment. The metabolizing rate is determined based on information of the metabolite diffusion gradient.Type: ApplicationFiled: December 23, 2003Publication date: May 11, 2006Inventors: Lars Damgaard, Jens Gunderson, Lars Ottosen, Niels Ramsing
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Publication number: 20050089889Abstract: The invention relates to nucleic acid probes, nucleic acid probe libraries, and kits for detecting, classifying, or quantitating components in a complex mixture of nucleic acids, such as a transcriptome, and methods of using the same. The invention also relates to methods of identifying nucleic acid probes useful in the probe libraries and to methods of identifying a means for detection of a given nucleic acid.Type: ApplicationFiled: June 18, 2004Publication date: April 28, 2005Inventors: Niels Ramsing, Peter Mouritzen, Soren Echwald, Niels Tolstrup
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Patent number: D869681Type: GrantFiled: January 26, 2016Date of Patent: December 10, 2019Assignee: VITROLIFE A/SInventors: Kim Bøndergaard Madsen, Jonas Lerche Hansen, Niels Ramsing