Patents by Inventor Nien-Yi Chen

Nien-Yi Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240128324
    Abstract: A field effect transistor includes a substrate having a transistor forming region thereon; an insulating layer on the substrate; a first graphene layer on the insulating layer within the transistor forming region; an etch stop layer on the first graphene layer within the transistor forming region; a first inter-layer dielectric layer on the etch stop layer; a gate trench recessed into the first inter-layer dielectric layer and the etch stop layer within the transistor forming region; a second graphene layer on interior surface of the gate trench; a gate dielectric layer on the second graphene layer and on the first inter-layer dielectric layer; and a gate electrode on the gate dielectric layer within the gate trench.
    Type: Application
    Filed: November 21, 2022
    Publication date: April 18, 2024
    Applicant: UNITED MICROELECTRONICS CORP.
    Inventors: Kuo-Chih Lai, Shih-Min Chou, Nien-Ting Ho, Wei-Ming Hsiao, Li-Han Chen, Szu-Yao Yu, Chung-Yi Chiu
  • Publication number: 20230100100
    Abstract: Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C?mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 30, 2023
    Applicant: Oneness Biotech Co., Ltd.
    Inventors: Kung-Ming Lu, Nien-Yi Chen, Tien-Tien Cheng
  • Patent number: 11439682
    Abstract: Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C?mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: September 13, 2022
    Assignee: Oneness Biotech Co., Ltd.
    Inventors: Kung-Ming Lu, Nien-Yi Chen, Tien-Tien Cheng
  • Publication number: 20200297815
    Abstract: Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C?mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.
    Type: Application
    Filed: April 29, 2020
    Publication date: September 24, 2020
    Applicant: Oneness Biotech Co., Ltd.
    Inventors: Kung-Ming Lu, Nien-Yi Chen, Tien-Tien Cheng
  • Patent number: 10745729
    Abstract: Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: August 18, 2020
    Assignee: Oneness Biotech Co. Ltd.
    Inventors: Nien-Yi Chen, Che-Haorz Wu, Hung-Chi Chen, Winston Town
  • Publication number: 20170145463
    Abstract: Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.
    Type: Application
    Filed: November 22, 2016
    Publication date: May 25, 2017
    Applicant: Fountain Biopharma Inc.
    Inventors: NIEN-YI CHEN, Che-Haorz Wu, Hung-Chi Chen, Winston Town
  • Patent number: 9587034
    Abstract: Antibodies binding to junction regions between the CH4 and C?mX domains of membrane-bound IgE and uses thereof in treating IgE-mediated diseases such as allergic diseases.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 7, 2017
    Assignee: Academia Sinica
    Inventors: Tse Wen Chang, Jiun-Bo Chen, Chien-Jen Lin, Nien-Yi Chen
  • Patent number: 9540673
    Abstract: Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: January 10, 2017
    Assignee: Fountain Biopharma Inc.
    Inventors: Nien-Yi Chen, Che-Haorz Wu, Hung-Chi Chen, Winston Town
  • Publication number: 20150259720
    Abstract: Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.
    Type: Application
    Filed: March 17, 2015
    Publication date: September 17, 2015
    Applicant: Fountain Biopharma Inc.
    Inventors: Nien-Yi Chen, Che-Haorz Wu, Hung-Chi Chen, Winston Town
  • Publication number: 20150086558
    Abstract: Antibodies binding to junction regions between the CH4 and C?mX domains of membrane-bound IgE and uses thereof in treating IgE-mediated diseases such as allergic diseases.
    Type: Application
    Filed: March 14, 2013
    Publication date: March 26, 2015
    Applicant: Academia Sinica
    Inventors: Tse Wen Chang, Jiun-Bo Chen, Chien-Jen Lin, Nien-Yi Chen
  • Patent number: 7482006
    Abstract: Provided is an antibody against enterovirus 71 comprising the amino acid sequence shown in SEQ ID NOS: 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, or 26 or functionally active homologues thereof. Also provided are methods for obtaining the antibody comprising (a) selecting a yeast expressing such an antibody from a yeast library, (b) culturing the yeast under conditions that the antibody is expressed, and (c) recovering the antibody from the culture. Also provided is a process for producing the antibody comprising (a) culturing a host cell under conditions that the antibody is expressed, (b) recovering the antibody from the culture, wherein the host cells are transformed or transfected for expressing the antibody against enterovirus 71. Also provided are pharmaceutical compositions comprising an antibody against enterovirus 71 and a pharmaceutically acceptable carrier or diluent, wherein the antibody has an anti-virus agent or detectable label attached thereto.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: January 27, 2009
    Assignee: Development Center for Biotechnology
    Inventors: Tse-Wen Chang, Jim Jinn-Chyuan Sheu, Lee-Hwa Lo, Nien-Yi Chen, Young-Sun Lin
  • Publication number: 20060257859
    Abstract: Provided is an antibody against enterovirus 71 comprising the amino acid sequence shown in SEQ ID NOS: 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, or 26 or functionally active homologues thereof. Also provided are methods for obtaining the antibody comprising (a) selecting a yeast expressing such an antibody from a yeast library, (b) culturing the yeast under conditions that the antibody is expressed, and (c) recovering the antibody from the culture. Also provided is a process for producing the antibody comprising (a) culturing a host cell under conditions that the antibody is expressed, (b) recovering the antibody from the culture, wherein the host cells are transformed or transfected for expressing the antibody against enterovirus 71. Also provided are pharmaceutical compositions comprising an antibody against enterovirus 71 and a pharmaceutically acceptable carrier or diluent, wherein the antibody has an anti-virus agent or detectable label attached thereto.
    Type: Application
    Filed: April 17, 2006
    Publication date: November 16, 2006
    Inventors: Tse-Wen Chang, Jim Sheu, Lee-Hwa Lo, Nien-Yi Chen, Young-Sun Lin