Patents by Inventor Nigel A. Langley
Nigel A. Langley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11744952Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set a delivery dose. An injector may include a housing, a cartridge containing a medicinal product, the cartridge being retained within the housing, means for selecting a dose of the medicinal product to be expelled, and means for expelling the selected dose of the medicinal product. The housing may be a unitary housing within which the means for selecting the dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston rod may rotate, ratchet means, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.Type: GrantFiled: October 15, 2021Date of Patent: September 5, 2023Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 11383042Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: GrantFiled: November 18, 2021Date of Patent: July 12, 2022Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20220072235Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: ApplicationFiled: November 18, 2021Publication date: March 10, 2022Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20220031954Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a cartridge containing medicinal product, the cartridge being retained within the housing, means for selecting a dose of medicinal product to be expelled, and means for expelling the selected dose of medicinal product. The housing may be a unitary housing within which the means for selecting a dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston may rotate, ratchet means, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.Type: ApplicationFiled: October 15, 2021Publication date: February 3, 2022Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 11207467Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: GrantFiled: January 22, 2019Date of Patent: December 28, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 11141534Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: GrantFiled: July 20, 2021Date of Patent: October 12, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20210163879Abstract: A method for stabilizing cells in cell culture production, the method comprising culturing a cell line capable of expressing proteins in cell culture media, and supplementing said cell culture media with a graft polymer in which N-vinyl caprolactam and vinyl acetate moieties are grafted on a polyethylene glycol backbone.Type: ApplicationFiled: December 7, 2018Publication date: June 3, 2021Inventors: Felicitas Guth, Karl Kolter, Nigel A. Langley, Kerri Gaumer Freidl, Kristina Brueggemann
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Patent number: 10967126Abstract: The present disclosure relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present disclosure.Type: GrantFiled: November 2, 2018Date of Patent: April 6, 2021Assignee: Sanofi-Aventis Deutschland GmbHInventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Patent number: 10781959Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.Type: GrantFiled: November 1, 2017Date of Patent: September 22, 2020Assignee: Sanofi-Aventis Deutschland GMBHInventors: David Plumptre, Christopher Nigel Langley, Richard James Vincent Avery, Joseph Butler
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Publication number: 20190175834Abstract: The present disclosure relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present disclosure.Type: ApplicationFiled: November 2, 2018Publication date: June 13, 2019Inventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Publication number: 20190151555Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: ApplicationFiled: January 22, 2019Publication date: May 23, 2019Inventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 10286150Abstract: The present invention relates to a drug delivery device (6) comprising a dose button (1). Furthermore it relates to a method for manufacturing a dose button (1) by using a cutting-off process. The aim of the present invention is to minimize the risk of using a drug delivery device (6) containing a wrong drug. By means of tactile features, a drug delivery device (6) is distinguishable from another drug delivery device (6) containing another type of drug. This tactile feature is manufactured by using a dose button (1) out of metal which is milled or lathed.Type: GrantFiled: March 31, 2010Date of Patent: May 14, 2019Inventors: Michael Harms, Steffen Raab, Udo Stauder, Richard James Vincent Avery, Christopher Nigel Langley, James Alexander Senior, James Alexander Davies
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Patent number: 10226579Abstract: The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.Type: GrantFiled: November 16, 2016Date of Patent: March 12, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 10213557Abstract: A medicament delivery device is shown for the administration of one or more drug agents. The device has a priming mode and a drug delivery mode for administering delivery of the one or more drug agents. The device comprises a controller configured to set the device in a priming mode when one or more predetermined states of the device are identified and to disable the drug delivery mode during said predetermined state(s). When states of the device are different from said predetermined states, the controller can set the device in the drug delivery mode. A priming mode may still be enabled through a user interface.Type: GrantFiled: January 20, 2017Date of Patent: February 26, 2019Assignee: Sanofi-Aventis Deutschland GmbHInventors: Ilona Eggert, Christopher Nigel Langley, Shane Alistair Day
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Patent number: 10207056Abstract: A set of members for a drug delivery device comprises at least two components for the device, wherein both components are provided with a marking, the markings being substantially equivalent or identical. Furthermore, a drug delivery device and a set of drug delivery devices are provided.Type: GrantFiled: March 30, 2011Date of Patent: February 19, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Richard James Vincent Avery, Christopher Nigel Langley, James Alexander Senior, James Alexander Davies
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Patent number: 10201661Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set a delivery dose. An injector may include a housing, a cartridge containing a medicinal product, the cartridge being retained within the housing, a dose setting mechanism to select a dose of the medicinal product to be expelled, and a dose delivery mechanism to expel the selected dose of the medicinal product. The housing may be a unitary housing within which the dose setting mechanism and the dose delivery mechanism are moveably retained.Type: GrantFiled: August 12, 2011Date of Patent: February 12, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Patent number: 10195353Abstract: A pen-type injector is improved so that a user may select a delivery dose of a medicinal product from a multidose cartridge. The injector includes a housing, a cartridge containing the medicinal product retained within the housing, a piston rod, a dose selecting member to select the dose of medicinal product to be expelled, and a drive member to expel the selected dose of the medicinal product. The housing is formed unitary so that the dose selecting member and the drive member are moveably retained within the housing. The injector may include a ratchet associated with an insert to ensure the piston rod only rotates in a single direction through the insert, a button located on the drive member, and a clutch which upon depression of the button prevents rotation between the dose selecting member and the drive member.Type: GrantFiled: June 30, 2014Date of Patent: February 5, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Robert Frederick Veasey, Christopher Nigel Langley, Steven Wimpenny
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Publication number: 20180353875Abstract: A process for purification of polyether block copolymers comprising polyoxyethylene and polyoxypropylene moieties using sequential multi-column size exclusion chromatography apparatus operated as a counter current moving bed wherein a process cycle comprises the steps of.Type: ApplicationFiled: December 12, 2016Publication date: December 13, 2018Inventors: Pedro Sa Gomes, Bastiaan Bram Pieter Staal, Felicitas Guth, Nigel A. Langley
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Patent number: 10117994Abstract: The present invention inter alia relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present invention.Type: GrantFiled: April 26, 2012Date of Patent: November 6, 2018Assignee: Sanofi-Aventis Deutschland GmbHInventors: Marc Holtwick, James Alexander Davies, Simon Lewis Bilton, David Moore, Steven Wimpenny, Christopher Nigel Langley
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Patent number: D862261Type: GrantFiled: December 6, 2017Date of Patent: October 8, 2019Inventors: James Mocroft, Michael John George, Christopher Nigel Langley