Patents by Inventor Nigel A. Swain

Nigel A. Swain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spirocyclic derivatives
    Patent number: 7507742
    Abstract: The invention provides compounds of formula (I): wherein: m is 0, 1 or 2; X is O, S or N—CN; R is F, Cl or CN; A is a C3-6 cycloalkylene group optionally substituted with a C1-4 alkyl group; and B is a single bond or a C1-2 alkylene group; or a pharmaceutically acceptable salt, solvate, polymorph or prodrug thereof. The compounds are PDE7 inhibitors and have a number of therapeutic applications, particularly in the treatment of pain, especially neuropathic pain.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: March 24, 2009
    Assignee: Pfizer Inc.
    Inventors: David J. Rawson, Nigel A. Swain
  • Spirocyclic Derivatives
    Publication number: 20070129388
    Abstract: The invention provides compounds of formula (I): wherein: m is 0, 1 or 2; X is O, S or N—CN; R is F, Cl or CN; A is a C3-6 cycloalkylene group optionally substituted with a C1-4 alkyl group; and B is a single bond or a C1-2 alkylene group; or a pharmaceutically acceptable salt, solvate, polymorph or prodrug thereof. The compounds are PDE7 inhibitors and have a number of therapeutic applications, particularly in the treatment of pain, especially neuropathic pain.
    Type: Application
    Filed: December 1, 2006
    Publication date: June 7, 2007
    Inventors: David Rawson, Nigel Swain