Patents by Inventor Nigel Allison

Nigel Allison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of protective antigen
    Patent number: 8440427
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: May 14, 2013
    Assignees: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • PREPARATION OF PROTECTIVE ANTIGEN
    Publication number: 20130017573
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Application
    Filed: June 27, 2012
    Publication date: January 17, 2013
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • Preparation of protective antigen
    Patent number: 8323927
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: December 4, 2012
    Assignees: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehra, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • PREPARATION OF PROTECTIVE ANTIGEN
    Publication number: 20120045794
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Application
    Filed: September 27, 2011
    Publication date: February 23, 2012
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • Preparation of protective antigen
    Patent number: 8101735
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: January 24, 2012
    Assignees: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • PREPARATION OF PROTECTIVE ANTIGEN
    Publication number: 20090042282
    Abstract: A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA.
    Type: Application
    Filed: March 4, 2008
    Publication date: February 12, 2009
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • protective antigen
    Patent number: 7355027
    Abstract: A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinant Bacillus anthracis Protective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinant Bacillus anthracis Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof. The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: April 8, 2008
    Assignees: Dynport Vaccine Company LLC, Health Protection Agency
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara T. Solow, Juan Arroyo, Randall K. Lapcevich
  • PREPARATION OF PROTECTIVE ANTIGEN
    Publication number: 20080020001
    Abstract: A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinant Bacillus anthracis Protective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinant Bacillus anthracis Protective Antigen (rPA). Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof. The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.
    Type: Application
    Filed: June 15, 2005
    Publication date: January 24, 2008
    Applicants: Health Protection Agency, Dynport Vaccine Company LLC
    Inventors: John Brehm, Ian McEntee, Philip Vincent, Nigel Allison, Rossalyn Brehm, George Jack, Michael Herbert, Barbara Solow, Juan Arroyo, Randall Lapcevich
  • SYSTEM AND METHOD FOR REGULATING A POWER SYSTEM WITH FEEDBACK USING CURRENT SENSING
    Publication number: 20030218448
    Abstract: A system (10) regulates current and voltage in a power system by using a correction signal that is modified to compensate for errors associated with manufacturing variations. The correction signal controls a power switch (49) that selectively sources/shunts current to/from the output load (26) and power source. The compensation technique applies to systems conducting either an A.C. or a D.C. voltage. A current controller (44) is placed in a control loop. The current controller contains circuitry having an offset voltage and loop gain errors as a result of manufacturing variations. At least one of the offset voltage and loop gain are dynamically calculated by a loop controller (38) and the result is used to modify the correction signal to provide an accurate output load voltage and power line current.
    Type: Application
    Filed: May 24, 2002
    Publication date: November 27, 2003
    Inventors: Petr Lidak, Nigel Allison
  • System and method for regulating a power system with feedback using current sensing
    Patent number: 6650092
    Abstract: A system (10) regulates current and voltage in a power system by using a correction signal that is modified to compensate for errors associated with manufacturing variations. The correction signal controls a power switch (49) that selectively sources/shunts current to/from the output load (26) and power source. The compensation technique applies to systems conducting either an A.C. or a D.C. voltage. A current controller (44) is placed in a control loop. The current controller contains circuitry having an offset voltage and loop gain errors as a result of manufacturing variations. At least one of the offset voltage and loop gain are dynamically calculated by a loop controller (38) and the result is used to modify the correction signal to provide an accurate output load voltage and power line current.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: November 18, 2003
    Assignee: Motorola, Inc.
    Inventors: Petr Lidak, Nigel Allison