Patents by Inventor Nigel Bosworth
Nigel Bosworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210252691Abstract: A storage device for storing cable ties or the like has a plurality of adjacent compartments extending in an axial direction parallel to one another. Retaining members in the form of magnets are provided on side walls of the compartments for releasably holding the device to a supporting structure in use. The compartments each have an open end to allow insertion of the cable tie and a closed end. The compartments have different axial lengths to accommodate different lengths of cable ties. The storage device may be releasably applied to the side of a tool chest or the like.Type: ApplicationFiled: February 18, 2021Publication date: August 19, 2021Inventor: Nigel Bosworth
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Patent number: 8372654Abstract: The invention is concerned with Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI), particularly NMR spectroscopy. It provides hyperpolarization methods offering enhanced sensitivity of detection over conventional NMR for studying the fate of a test compound in a biological system. The methods are particularly suitable for studying metabolism and toxicity of drugs. The resulting NMR sensitivity increase is advantageous in two key aspects of NMR detection: test compounds can be detected at lower concentrations and substantial time saving can be achieved in cases where extensive averaging is conventionally employed to increase the signal to noise ratio of the corresponding NMR spectra. The methods can be used for studios that were not practical or not possible using conventional NMR.Type: GrantFiled: June 12, 2001Date of Patent: February 12, 2013Assignee: GE Healthcare LimitedInventors: Neil Cook, Albie Santos, Nigel Bosworth, Jan Wolber, Mike Looker, Peter Knox, Jan Jenrik Ardenkjaer-Larsen, Klaes Golman
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Patent number: 8148539Abstract: Disclosed are cyanine dyes that are useful for labelling and detecting biological and other materials. The dyes are of formula (I): in which groups R3 and R4 are attached to the Z1 ring structure and groups R5 and R6 are attached to the Z2 ring structure, and n=1, 2 or 3; Z1 and Z2 independently represent the carbon atoms necessary to complete a one ring, or two-fused ring aromatic system; at least one of groups R1, R2, R3, R4, R5, R6 and R7 is the group -E-F where E is a single bond or a spacer group and F is a target bonding group; one or more of groups R11, R12, R13 and R14 are independently selected from the group —(CH2)k—W, where W is sulphonic acid or phosphonic acid and k is an integer from 1 to 10.Type: GrantFiled: July 1, 2010Date of Patent: April 3, 2012Assignees: GE Healthcare UK Limited, Carnegie Mellon UniversityInventors: Richard M. West, Nigel Bosworth, Ratnakar B. Mujumdar
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Publication number: 20100267937Abstract: Disclosed are cyanine dyes that are useful for labelling and detecting biological and other materials. The dyes are of formula (I): in which groups R3 and R4 are attached to the Z1 ring structure and groups R5 and R6 are attached to the Z2 ring structure, and n=1, 2 or 3; Z1 and Z2 independently represent the carbon atoms necessary to complete a one ring, or two-fused ring aromatic system; at least one of groups R1, R2, R3, R4, R5, R6 and R7 is the group -E-F where E is a single bond or a spacer group and F is a target bonding group; one or more of groups R11, R12, R13 and R14 are independently selected from the group —(CH2)k—W, where W is sulphonic acid or phosphonic acid and k is an integer from 1 to 10.Type: ApplicationFiled: July 1, 2010Publication date: October 21, 2010Inventors: Richard M. West, Nigel Bosworth, Ratnakar B. Mujumdar
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Patent number: 7750163Abstract: Disclosed are cyanine dyes that are useful for labeling and detecting biological and other materials. The dyes are of formula (I) in which groups R3 and R4 are attached to the Z1 ring structure and groups R5 and R6 are attached to the Z2 ring structure, and n=1, 2 or 3; Z1 and Z2 independently represent the carbon atoms necessary to complete a one ring, or two-fused ring aromatic system; at least one of groups R1, R2, R3, R4, R5, R6 and R7 is the group -E-F where E is a single bond or a spacer group and F is a target bonding group; one or more of groups R11, R12, R13 and R14 are independently selected from the group —(CH2)k—W, where W is sulphonic acid or phosphonic acid and k is an integer from 1 to 10.Type: GrantFiled: October 29, 2004Date of Patent: July 6, 2010Assignees: GE Healthcare U.K. Limited, Carnegie Mellon UniversityInventors: Richard M. West, Nigel Bosworth, Ratnakar B. Mujumdar
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Publication number: 20070203343Abstract: Disclosed are cyanine dyes that are useful for labeling and detecting biological and other materials. The dyes are of formula (I) in which groups R3 and R4 are attached to the Z1 ring structure and groups R5 and R6 are attached to the Z2 ring structure, and n=1, 2 or 3; Z1 and Z2 independently represent the carbon atoms necessary to complete a one ring, or two-fused ring aromatic system; at least one of groups R1, R2, R3, R4, R5, R6 and R7 is the group -E-F where E is a single bond or a spacer group and F is a target bonding group; one or more of groups R11, R12, R13 and R14 are independently selected from the group —(CH2)k—W, where W is sulphonic acid or phosphonic acid and k is an integer from 1 to 10.Type: ApplicationFiled: October 29, 2004Publication date: August 30, 2007Inventors: Richard West, Nigel Bosworth, Ratnakar Mujumdar
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Patent number: 6828116Abstract: Disclosed is a non-fluorescent cyanine dye that may be used as an acceptor in fluorescence energy transfer assays involving the detection of binding and/or cleavage events in reactions involving biological molecules, and assay methods utilising such dyes.Type: GrantFiled: February 15, 2001Date of Patent: December 7, 2004Assignee: Amersham Biosciences UK LimitedInventors: Alan L. Hamilton, Martyn N. Birch, Malcolm J. Hatcher, Nigel Bosworth, Brian Scott
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Publication number: 20040039281Abstract: The invention is concerned with Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI), particularly NMR spectroscopy. It provides hyperpolarisation methods offering enhanced sensitivity of detection over conventional NMR for studying the fate of a test compound in a biological system. The methods are particularly suitable for studying metabolism and toxicity of drugs. The resulting NMR sensitivity increase is advantageous in two key aspects of NMR detection: test compounds can be detected at lower concentrations and substantial time saving can be achieved in cases where extensive averaging is conventionaly employed to increase the signal to noise ratio of the corresponding NMR spectra. The methods can be used for studios that were not practical or not possible using conventional NMR.Type: ApplicationFiled: July 17, 2003Publication date: February 26, 2004Inventors: Neil Cook, Albie Santos, Nigel Bosworth, Jan Wolber, Mike Looker, Peter Knox, Jan Jenrik Ardenkjaer-Larsen, Klaes Golman
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Patent number: 5658494Abstract: Novel compounds obtainable by reacting together an imido-reagent such as diphenylphosphonimido-triphenylphosphorane), or a phosphine oxide such as p-tolyldiphenylphosphine oxide, with a chelate of a transition or lanthanide or actinide metal, such as tris(dibenzoylmethide)europium III, have the property of fluorescing in UV radiation. The invention includes solid polymer bodies containing such compounds, or chelates of transition or lanthanide or actinide metals generally, the bodies having the property of emitting light or infra-red radiation when subjected to a flux of ultra-violet or ionising radiation by virtue of internally generated, e.g. by tritium ionising radiation. The body is preferably of polystyrene formed by polymerising the monomer in the presence of the compound or metal chelate.Type: GrantFiled: May 22, 1995Date of Patent: August 19, 1997Assignee: Amersham International plcInventors: Colin David Bell, John Hewer Coles Howse, Nigel Bosworth, David Martin James
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Patent number: D506953Type: GrantFiled: December 6, 2002Date of Patent: July 5, 2005Assignee: Brumby Corporation Ltd.Inventors: Stephen Everitt, Benjamin Wood, Nigel Bosworth, Stephen Thompson, Carl Fogarty, Gavin Palmer, Dan Horstmann, Clive Kilford, Nicholas Carpenter, David Minty
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Patent number: D511920Type: GrantFiled: January 23, 2003Date of Patent: November 29, 2005Assignee: Brumby Corporation LimitedInventor: Nigel Bosworth
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Patent number: D520410Type: GrantFiled: December 6, 2002Date of Patent: May 9, 2006Assignee: Brumby Corporation LimitedInventors: Michael Fisher, Michaela Fogarty, Nigel Bosworth, Murray Treece, Neil Bramwell, Carl Fogarty
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Patent number: D520797Type: GrantFiled: January 23, 2003Date of Patent: May 16, 2006Assignee: Brumby Corporation LimitedInventor: Nigel Bosworth
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Patent number: D496608Type: GrantFiled: December 6, 2002Date of Patent: September 28, 2004Assignee: Brumby Corporation LimitedInventors: Stephen Everitt, Benjamin Wood, Nigel Bosworth, Stephen Thompson, Carl Fogarty, Gavin Palmer, Dan Horstmann, Clive Kilford, Nicholas Carpenter, David Minty, Lawrence Cutts, Tony White, Peter Dresser