Patents by Inventor Nigel D. Walshe

Nigel D. Walshe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiparasitic terpene alkaloids
    Patent number: 7494992
    Abstract: The present invention relates to novel terpene alkaloids and their use as antiparasitic agents. The present invention also relates to an antiparasitic agent which comprises a terpene alkaloid compound of this invention as an effective ingredient in an antiparasitic formulation. More particularly, the present invention relates to derivatives of the terpene alkaloid (1S,2R,4aS,5R,8R,8aR)-2-(acetyloxy)-8a-hydroxy-3,8-dimethyl-5-(1-methylethenyl)-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl (2S,3aR,9bR)-6-chloro-9b-hydroxy-5-methyl-1,2,3,3a,5,9b-hexahydropyrrolo[2,3-c][2,1]benzoxazine-2-carboxylate. Pharmaceutical compositions comprising the same are also disclosed.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: February 24, 2009
    Assignee: Pfizer Inc.
    Inventors: Nathan A. Chubb, Douglas J. Critcher, James J. Eshelby, Graham Lunn, Andrew J. Rudge, Nigel D. Walshe, Paul H Wiedenau, David H. Williams
  • Process for antiparasitic agent
    Patent number: 6906184
    Abstract: An improved process for the preparation of the antiparasitic compound 25-cyclohexyl-22,23-dihydro-5-hydroxyiminoavermectin B1 monosaccharide from doramectine and intermediates therefor and crystalline solvates thereof.
    Type: Grant
    Filed: July 23, 1998
    Date of Patent: June 14, 2005
    Assignee: Pifzer, Inc.
    Inventors: Nigel D. Walshe, Selena J. Cambers