Patents by Inventor Nigel Dennis Stow

Nigel Dennis Stow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-herpesviral agent
    Patent number: 6337074
    Abstract: An antiviral agent capable of disrupting the association of two viral proteins required for DNA replication in herpesviruses. The agents disrupt the association of UL8 and POL in HSV-1 or the association of equivalent homologues of these proteins in other herpesviruses (for example UL 102 and UL54 in HCMV). Suitable agents are peptides which mimic the C-terminal or C-proximal portion of UL8 (or its homologues) for example the peptide IELVFTGVLAGVWGEGGKFV. Peptidomimetic compounds of such peptides are also suitable anti-viral agents. An assay to test for agents capable of disrupting association of POL and UL8 (or homologues thereof) is also described.
    Type: Grant
    Filed: January 25, 1999
    Date of Patent: January 8, 2002
    Assignee: Medical Research Council
    Inventors: Howard Sinkinson Marsden, Nigel Dennis Stow, Gordon William McLean