Patents by Inventor Nigel Dunn-Coleman

Nigel Dunn-Coleman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACID FUNGAL PROTEASES
    Publication number: 20090061483
    Abstract: The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and host cells including nucleic acid sequences coding for the proteases, methods for producing the proteases, enzyme compositions and methods employing said proteases.
    Type: Application
    Filed: July 2, 2008
    Publication date: March 5, 2009
    Inventors: Kathleen A. Clarkson, Nigel Dunn-Coleman, Suzanne E. Lantz, Craig E. Pilgrim, Piet Van Solingen, Michael Ward
  • Heterologous alpha amylase expression in
    Patent number: 7498159
    Abstract: The present invention relates to the co-expression and production of a heterologous alpha amylase and an endogenous glucoamylase in an Aspergillus strain and enzyme compositions including the same.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: March 3, 2009
    Assignee: Genencor International, Inc.
    Inventors: Toby M. Baldwin, Kathleen A. Clarkson, Nigel Dunn-Coleman, Suzanne E. Lantz
  • Trichoderma reesei glucoamylase and homologs thereof
    Patent number: 7494685
    Abstract: The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for the glucoamylases, vectors and host cells incorporating the DNA sequences, enzyme compositions and methods of using the glucoamylases in various applications.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: February 24, 2009
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Paulien Neefe-Kruithof, Craig E. Pilgrim, Piet Van Solingen, Donald E. Ward
  • EGVI Endoglucanase and Nucleic Acids Encoding the Same
    Publication number: 20090036648
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Application
    Filed: November 13, 2007
    Publication date: February 5, 2009
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • TRICHODERMA REESEI GLUCOAMYLASE AND HOMOLOGS THEREOF
    Publication number: 20080299619
    Abstract: The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for the glucoamylases, vectors and host cells incorporating the DNA sequences, enzyme compositions and methods of using the glucoamylases in various applications.
    Type: Application
    Filed: July 21, 2008
    Publication date: December 4, 2008
    Applicant: GENENCOR INTERNATIONAL, INC.
    Inventors: Nigel Dunn-Coleman, Paulien Neefe-Kruithof, Craig E. Pilgrim, Piet Van Solingen, Donald E. Ward
  • Manipulation of the phenolic acid content and digestibility of plant cell walls by targeted expression of genes encoding cell wall degrading enzymes
    Patent number: 7453023
    Abstract: Described herein are methods to enhance the production of more highly fermentable carbohydrates in plants, especially forage grasses. The invention provides for transgenic plants transformed with expression vectors containing a DNA sequence encoding ferulic acid esterase I from Aspergillus, preferably A. niger. The expression vectors may optionally comprise a DNA sequence encoding xylanase from Trichoderma, preferably T. reesei. Expression of the enzyme(s) is targeted to specific cellular compartments, in specific tissues and under specific environmental conditions. Uses of this invention include, but are not limited to, forage with improved digestibility for livestock, and enhanced biomass conversion.
    Type: Grant
    Filed: August 30, 2005
    Date of Patent: November 18, 2008
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Timothy Langdon, Phillip Morris
  • EGVII endoglucanase and nucleic acids encoding the same
    Patent number: 7449319
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: November 11, 2008
    Assignee: Daniaco A/S, Genencor Division
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Acid fungal proteases
    Patent number: 7429476
    Abstract: The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and host cells including nucleic acid sequences coding for the proteases, methods for producing the proteases, enzyme compositions and methods employing said proteases.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: September 30, 2008
    Assignee: Genencor International, Inc.
    Inventors: Kathleen A. Clarkson, Nigel Dunn-Coleman, Suzanne E. Lantz, Craig E. Pilgrim, Piet van Solingen, Michael Ward
  • Regulatable growth of filamentous fungi
    Patent number: 7425450
    Abstract: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: September 16, 2008
    Assignee: Genencor International, Inc.
    Inventors: Ali R. Akin, Elizabeth A. Bodie, Shirley M. Burrow, Nigel Dunn-Coleman, Geoffrey Turner, Michael Ward
  • Aspergillus Kawachi Acid-Stable Alpha Amylase and Applications in Granular Starch Hydrolysis
    Publication number: 20080199927
    Abstract: The present invention relates to a method for producing an end product and particularly an alcohol which comprises contacting a granular starch substrate with an acid-stable alpha amylase (asAA) having granular starch hydrolyzing (GSH) activity and a glucoamylase (GA) in a fermentation step which also comprises ethanologenic microorganisms at a temperature between about 25 to 65° C. and producing an end-product.
    Type: Application
    Filed: May 24, 2005
    Publication date: August 21, 2008
    Inventors: Nigel Dunn-Coleman, Susan M. Fiske, Oreste J. Lantero, Suzanne E. Lantz, Michael J. Pepsin, Jayarama K. Shetty
  • glucoamylase and homologs thereof
    Patent number: 7413879
    Abstract: The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for the glucoamylases, vectors and host cells incorporating the DNA sequences, enzyme compositions and methods of using the glucoamylases in various applications.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: August 19, 2008
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Paulien Neefe-Kruithof, Craig E. Pilgrim, Piet van Solingen, Donald E. Ward
  • glucoamylase and homologs thereof
    Patent number: 7413887
    Abstract: The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for the glucoamylases, vectors and host cells incorporating the DNA sequences, enzyme compositions and methods of using the glucoamylases in various applications.
    Type: Grant
    Filed: October 7, 2005
    Date of Patent: August 19, 2008
    Assignee: Genecor International, Inc.
    Inventors: Nigel Dunn-Coleman, Paulien Neefe-Kruithof, Craig E. Pilgrim, Piet Van Solingen, Donald E. Ward
  • BGL7 beta-glucosidase and nucleic acids encoding the same
    Patent number: 7407788
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: August 5, 2008
    Assignee: Danisco A/S, Genencor Division
    Inventors: Nigel Dunn-Coleman, Michael Ward
  • BGL5 Beta-glucosidase and nucleic acids encoding the same
    Publication number: 20080176282
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant BGL5 proteins and methods for producing the same.
    Type: Application
    Filed: September 12, 2007
    Publication date: July 24, 2008
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Acid-Stable Alpha Amylases having Granular Starch Hydrolyzing Activity and Enzyme Compositions
    Publication number: 20080153136
    Abstract: The present invention relates to an acid-stable alpha amylase (asAA) derived from a strain of Aspergillus kawachi, which has granular starch hydrolyzing (GSH) activity, the heterologous expression of the asAA having GSH activity in filamentous fungal host cells and enzyme compositions including the same which optionally include glucoamylase.
    Type: Application
    Filed: January 30, 2008
    Publication date: June 26, 2008
    Inventors: Nigel Dunn-Coleman, Susan M. Fiske, Suzanne E. Lantz, Paulien Neefe-Kruithof, Michael J. Pepsin, Jayarama K. Shetty
  • Heterologous alpha amylase expression in aspergillus
    Publication number: 20080124764
    Abstract: The present invention relates to the co-expression and production of a heterologous alpha amylase and an endogenous glucoamylase in an Aspergillus strain and enzyme compositions including the same.
    Type: Application
    Filed: December 3, 2007
    Publication date: May 29, 2008
    Inventors: Toby M. Baldwin, Kathleen A. Clarkson, Nigel Dunn-Coleman, Suzanne E. Lantz
  • Expression of Granular Starch Hydrolyzing Enzyme in Trichoderma
    Publication number: 20080108125
    Abstract: The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having glucoamylase activity.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 8, 2008
    Inventors: Toby Baldwin, Benjamin Bower, Nigel Dunn-Coleman, Suzanne Lantz, Michael Pepsin
  • BGL3 Beta-Glucosidase and nucleic acids encoding the same
    Publication number: 20080095889
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
    Type: Application
    Filed: August 17, 2007
    Publication date: April 24, 2008
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions
    Patent number: 7354752
    Abstract: The present invention relates to an acid-stable alpha amylase (asAA) derived from a strain of Aspergillus kawachi, which has granular starch hydrolyzing (GSH) activity, the heterologous expression of the asAA having GSH activity in filamentous fungal host cells and enzyme compositions including the same which optionally include glucoamylase.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: April 8, 2008
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Susan M. Fiske, Suzanne E. Lantz, Paulien Neefe-Kruithof, Michael J. Pepsin, Jayarama K. Shetty
  • BGL3 beta-glucosidase and nucleic acids encoding the same
    Patent number: 7351573
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: April 1, 2008
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao