Patents by Inventor Nigel Dunne

Nigel Dunne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis
    Publication number: 20060246562
    Abstract: Recombinant organisms are provided comprising genes encoding cob(II)alamin reductase, cob(I)alamin adenosyltransferase, glycerol dehydratase and 1,3-propanediol oxidoreductase activities useful for the production of 1,3-propanediol from a variety of carbon substrates.
    Type: Application
    Filed: June 29, 2006
    Publication date: November 2, 2006
    Inventors: Nigel Dunn-Coleman, Anthony Gatenby, Fernando Valle
  • EGVI endoglucanase and nucleic acids encoding the same
    Publication number: 20060166322
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Application
    Filed: January 10, 2006
    Publication date: July 27, 2006
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Acid fungal protease in fermentation of insoluble starch substrates
    Publication number: 20060154353
    Abstract: The invention is directed to methods of producing ethanol and decreasing residual starch production in a no cook fermentation comprising contacting granular starch containing substrates with a granular starch hydrolyzing enzyme, a protease, and a fermenting microorganism under suitable fermentation conditions at a temperature below the starch gelatinization temperature of the starch substrate to produce ethanol, wherein the ethanol production is increased and the amount of residual starch is decreased compared to a substantially similar method conducted without the protease.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 13, 2006
    Inventors: Gang Duan, Nigel Dunn-Coleman, Oreste Lantero, Craig Pilgrim, Jayarama Shetty
  • EGVI endoglucanase and nucleic acids encoding the same
    Publication number: 20060154844
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Application
    Filed: January 10, 2006
    Publication date: July 13, 2006
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Acid fungal proteases
    Publication number: 20060154342
    Abstract: The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and host cells including nucleic acid sequences coding for the proteases, methods for producing the proteases, enzyme compositions and methods employing said proteases.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 13, 2006
    Inventors: Kathleen Clarkson, Nigel Dunn-Coleman, Suzanne Lantz, Craig Pilgrim, Piet Van Solingen, Michael Ward
  • EGVII endoglucanase and nucleic acids encoding the same
    Publication number: 20060141601
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Application
    Filed: January 10, 2006
    Publication date: June 29, 2006
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • EGVII endoglucanase and nucleic acids encoding the same
    Publication number: 20060135388
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Application
    Filed: January 10, 2006
    Publication date: June 22, 2006
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Heterologous alpha amylase expression in Aspergillus
    Publication number: 20060134747
    Abstract: The present invention relates to the co-expression and production of a heterologous alpha amylase and an endogenous glucoamylase in an Aspergillus strain and enzyme compositions including the same.
    Type: Application
    Filed: November 8, 2005
    Publication date: June 22, 2006
    Inventors: Toby Baldwin, Kathleen Clarkson, Nigel Dunn-Coleman, Suzanne Lantz
  • Heterologous expression of an Aspergillus kawachi acid-stable alpha amylase and applications in granular starch hydrolysis
    Publication number: 20060121589
    Abstract: The present invention relates to a granular starch hydrolyzing enzyme composition comprising an acid stable alpha amylase (asAA) having granular starch hydrolyzing activity. The invention also relates to a one-step method for producing an alcohol which comprises contacting a granular starch substrate with an acid-stable alpha amylase (asAA) having granular starch hydrolyzing (GSH) activity and a glucoamylase (GA) in a fermentation step which also comprises ethanologenic microorganisms at a temperature of 25-40° C. to obtain a fermentation broth having 5 to 20% ethanol.
    Type: Application
    Filed: February 6, 2006
    Publication date: June 8, 2006
    Inventors: Nigel Dunn-Coleman, Oreste Lantero, Suzanne Lantz, Michael Pepsin, Jayarama Shetty
  • EGVI endoglucanase and nucleic acids encoding the same
    Patent number: 7056721
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: June 6, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • EGVIII endoglucanase and nucleic acids encoding the same
    Patent number: 7049125
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl8, and the corresponding EGVIII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVIII, recombinant EGVIII proteins and methods for producing the same.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: May 23, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • EGVII endoglucanase and nucleic acids encoding the same
    Patent number: 7045331
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: May 16, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • BGL4 ?-glucosidase and nucleic acids encoding the same
    Patent number: 7045332
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL4, recombinant BGL4 proteins and methods for producing the same.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: May 16, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Trichoderma reesei glucoamylase and homologs thereof
    Publication number: 20060094080
    Abstract: The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for the glucoamylases, vectors and host cells incorporating the DNA sequences, enzyme compositions and methods of using the glucoamylases in various applications.
    Type: Application
    Filed: October 7, 2005
    Publication date: May 4, 2006
    Inventors: Nigel Dunn-Coleman, Paulien Neefe-Kruithof, Craig Pilgrim, Piet Van Solingen, Donald Ward
  • Heterologous expression of an acid-stable alpha amylase and applications in granular starch hydrolysis
    Patent number: 7037704
    Abstract: The present invention relates to a granular starch hydrolyzing enzyme composition comprising an acid stable alpha amylase (asAA) having granular starch hydrolyzing activity. The invention also relates to a one-step method for producing an alcohol which comprises contacting a granular starch substrate with an acid-stable alpha amylase (asAA) having granular starch hydrolyzing (GSH) activity and a glucoamylase (GA) in a fermentation step which also comprises ethanologenic microorganisms at a temperature of 25–40° C. to obtain a fermentation broth having 5 to 20% ethanol.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: May 2, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Oreste J. Lantero, Jr., Suzanne E. Lantz, Michael J. Pepsin, Jayarama K. Shetty
  • BGL4 beta-glucosidase and nucleic acids encoding the same
    Publication number: 20060046284
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL4, recombinant BGL4 proteins and methods for producing the same.
    Type: Application
    Filed: August 22, 2005
    Publication date: March 2, 2006
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • BGL5 ?-glucosidase and nucleic acids encoding the same
    Patent number: 7005289
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant BGL5 proteins and methods for producing the same.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: February 28, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Hyphal growth in fungi
    Patent number: 6995239
    Abstract: The present invention provides a method for producing desired proteins or chemicals in fungal host cells which comprise modulating the nucleic acid encoding proteins associated with hyphal growth. The amino acid and nucleic acid sequence of hbrA is provided.
    Type: Grant
    Filed: March 24, 1999
    Date of Patent: February 7, 2006
    Assignees: Genencor International, Inc., University of Sheffield
    Inventors: Nigel Dunn-Coleman, Geoffrey Turner, Sarah E. Pollerman, Stephen D. Memmott
  • Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions
    Publication number: 20060003408
    Abstract: The present invention relates to an acid-stable alpha amylase (asAA) derived from a strain of Aspergillus kawachi, which has granular starch hydrolyzing (GSH) activity, the heterologous expression of the asAA having GSH activity in filamentous fungal host cells and enzyme compositions including the same which optionally include glucoamylase.
    Type: Application
    Filed: May 24, 2005
    Publication date: January 5, 2006
    Inventors: Nigel Dunn-Coleman, Susan Fiske, Suzanne Lantz, Paulien Neefe-Kruithof, Michael Pepsin, Jayarama Shetty
  • Manipulation of the phenolic acid content and digestibility of plant cell walls by targeted expression of genes encoding cell wall degrading enzymes
    Publication number: 20060005270
    Abstract: Described herein are methods to enhance the production of more highly fermentable carbohydrates in plants, especially forage grasses. The invention provides for transgenic plants transformed with expression vectors containing a DNA sequence encoding ferulic acid esterase I from Aspergillus, preferably A. niger. The expression vectors may optionally comprise a DNA sequence encoding xylanase from Trichoderma, preferably T. reesei. Expression of the enzyme(s) is targeted to specific cellular compartments, in specific tissues and under specific environmental conditions. Uses of this invention include, but are not limited to, forage with improved digestibility for livestock, and enhanced biomass conversion.
    Type: Application
    Filed: August 30, 2005
    Publication date: January 5, 2006
    Inventors: Nigel Dunn-Coleman, Timothy Langdon, Phillip Morris