Patents by Inventor Nigel J. Otto

Nigel J. Otto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of producing testosteronan polymers using testosteronan synthase
    Patent number: 10273517
    Abstract: Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: April 30, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Nigel J. Otto
  • Methods of Producing Testosteronan Polymers Using Testosteronan Synthase
    Publication number: 20170247732
    Abstract: Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Inventors: Paul L. DeAngelis, Nigel J. Otto
  • Methods of producing testosteronan polymers using testosteronan synthase
    Patent number: 9695427
    Abstract: Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: July 4, 2017
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Nigel J. Otto
  • TESTOSTERONAN, A NOVEL HEPAROSAN ANALOG, TESTOSTERONAN SYNTHASE, AND METHODS OF PRODUCTION AND USE THEREOF
    Publication number: 20140154753
    Abstract: Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n.
    Type: Application
    Filed: January 31, 2012
    Publication date: June 5, 2014
    Applicant: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Nigel J. Otto