Patents by Inventor Nigel James MacLachlan

Nigel James MacLachlan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine Against African Horse Sickness Virus
    Publication number: 20140120133
    Abstract: The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a horse against African horse sickness virus, compositions comprising said vectors, methods of vaccination against African horse sickness virus, and kits for use with such methods and compositions.
    Type: Application
    Filed: October 22, 2013
    Publication date: May 1, 2014
    Applicants: MERIAL LIMITED, UNIVERSITY OF PRETORIA, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jules Maarten Minke, Jean Christophe Audonnet, Alan John Guthrie, Nigel James Maclachlan, Jiansheng Yao
  • VACCINE AGAINST AFRICAN HORSE SICKNESS VIRUS
    Publication number: 20120114691
    Abstract: The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a horse against African horse sickness virus, compositions comprising said vectors, methods of vaccination against African horse sickness virus, and kits for use with such methods and compositions.
    Type: Application
    Filed: January 25, 2012
    Publication date: May 10, 2012
    Inventors: Jules Maarten Minke, Jean-Christophe Audonnet, Alan John Guthrie, Nigel James Maclachlan, Jiansheng Yao
  • Vaccine against african horse sickness virus
    Patent number: 8168200
    Abstract: The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a horse against African horse sickness virus, compositions comprising said vectors, methods of vaccination against African horse sickness virus, and kits for use with such methods and compositions.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: May 1, 2012
    Assignees: Merial Limited, The Regents of the University of California, University of Pretoria
    Inventors: Jules Maarten Minke, Jean-Christophe Audonnet, Alan John Guthrie, Nigel James MacLachlan, Jiansheng Yao
  • Recombinant vaccine against bluetongue virus
    Patent number: 7862821
    Abstract: The present invention relates to an immunogenic or vaccine composition to induce an immune response or protective immune response against Orbiviruses, more specifically bluetongue virus (BTV) in an animal susceptible to BTV infection. The composition may include a pharmaceutically or veterinarily acceptable vehicle or excipient, and a vector. The vector may contain heterologous nucleic acid molecule(s), expresses in vivo in the animal BTV antigen, immunogen or epitope thereof, e.g., BTV VP2; BTV VP2 and VP5; BTV VP2 and VP5 and VP3 and/or VP7. The composition can contain an adjuvant, such as carbomer. Methods for making and using such a composition, including prime-boost regimes and including as to differential diagnosis, are also contemplated.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: January 4, 2011
    Assignees: Merial Limited, The Regents of the University of California
    Inventors: Jean Christophe Francis Audonnet, Kemal Karaca, Jiansheng Yao, Nigel James MacLachlan
  • VACCINE AGAINST AFRICAN HORSE SICKNESS VIRUS
    Publication number: 20100119546
    Abstract: The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a horse against African horse sickness virus, compositions comprising said vectors, methods of vaccination against African horse sickness virus, and kits for use with such methods and compositions.
    Type: Application
    Filed: October 22, 2009
    Publication date: May 13, 2010
    Inventors: Jules Maarten Minke, Jean-Christophe Audonnet, Alan John Guthrie, Nigel James Maclachlan, Jiansheng Yao
  • Recombinant vaccine against bluetongue virus
    Publication number: 20070280960
    Abstract: The present invention relates to an immunogenic or vaccine composition to induce an immune response or protective immune response against Orbiviruses, more specifically bluetongue virus (BTV) in an animal susceptible to BTV infection. The composition may include a pharmaceutically or veterinarily acceptable vehicle or excipient, and a vector. The vector may contain heterologous nucleic acid molecule(s), expresses in vivo in the animal BTV antigen, immunogen or epitope thereof, e.g., BTV VP2; BTV VP2 and VP5; BTV VP2 and VP5 and VP3 and/or VP7. The composition can contain an adjuvant, such as carbomer. Methods for making and using such a composition, including prime-boost regimes and including as to differential diagnosis, are also contemplated.
    Type: Application
    Filed: June 1, 2006
    Publication date: December 6, 2007
    Inventors: Jean Christophe Francis Audonnet, Kemal Karaca, Jiansheng Yao, Nigel James MacLachlan