Abstract: The invention is directed to certain novel compounds. Specifically, crystalline forms of N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide and crystalline 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole, along with salts thereof.

Abstract: The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.

Abstract: The present invention relates to a compound of formula (I), wherein CKE is of sub-formula (A) and/or (B), wherein: R1 is methyl or methoxy; R2 is hydrogen, methyl, ethyl, n-propyl, n-butyl, cyclopropyl, ethynyl, cyano, C1-C3alkoxy, C1-C2fluoroalkoxy, (difluoro)vinyloxy, C1-C2alkoxy-C1-C3alkoxy-, or C1fluoroalkoxy-C1C3alkoxy-; and X is NR4 or CR5R6; wherein R3, R4, R5 and R6 are as defined herein; wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.

Abstract: There is provided a method of operating a server in order to generate a verification code that is to be applied to a token associated with an offer that has been claimed by a user. The method comprises determining a unique offer identifier that has been assigned to the offer (B2a), generating a unique token identifier for the token (B2b), and determining a claim number that is representative of the total number of claims of the offer that have been made by the user (B2c). The verification code is then formed by concatenating at least the unique offer identifier, the unique token identifier, and the claim number.

Abstract: There is provided a method of operating a computer system in order to generate a plurality of graphical user interfaces. The method comprises storing a common data set comprising a plurality of data objects, each data object indicating a type for the data object, and storing graphical user interface generation information for each of the plurality of graphical user interfaces, the graphical user interface generation information of each graphical user interface defining a type of graphical user interface element that is to be used to represent each data object type on the graphical user interface. The method further comprises, upon receipt of a request for one of the plurality of graphical user interfaces, creating one or more graphical user interface elements for each data object in the common data set, wherein the type of graphical user interface elements created for a data object is determined using the corresponding graphical user interface generation information.

Abstract: The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclopentane-1,3-dione-2-yl, a cyclohexane-1,3, 5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, or a cycloheptane-1,3-dione-2-yl, or a derivative thereof (e.g. a fused such as fused bicyclic derivative, and/or a spirocyclic derivative), or an enol ketone tautomer derivative thereof, wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is —O—R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or —CH2CH2OCH3. These compounds are suitable for use as herbicides.

Abstract: There is proposed a method of producing an integrally bladed rotor, preferably a so-called “blisk” for a turbomachine, the method including the steps of: providing a rotor disc having a plurality of spaced-apart radial protrusions formed integrally around its perimeter; and forming a respective aerofoil-shaped blade extending radially generally outwardly from each of the protrusions via laser deposition. Each protrusion preferably extends radially outwardly from a circumferential body part of the rotor disc by a distance which is greater than the radially inward penetration of a heat-affected zone arising from the laser deposition used to form the respective blade.

Abstract: The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.

Abstract: The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclohexane-1,3,5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, a cycloheptane-1,3-dione-2-yl, in which each cyclic dione is bridged by alkanediyl, or a derivative thereof (e.g. an enol ketone tautomer derivative thereof), wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is —O—R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or —CH2CH2OCH3. These compounds are suitable for use as herbicides.

Abstract: The present invention is directed to compounds for use in the treatment or prevention of influenza virus infection.

Abstract: A subsea manifold-riser system is redeployed from a first production location to a second production location. A manifold module is lowered to the ocean floor at the first production location using a marine riser as a running tool by adding threaded pipe sections to the upper end of the marine riser. The manifold module is raised from the ocean floor at the first production location for redeployment at the second production location using the marine riser as a retrieval tool by removing threaded pipe sections from the upper end of the marine riser.

Abstract: The present invention relates to a compound of formula (I), wherein: X is methyl or chlorine; R1 is methyl or chlorine; R2 is hydrogen, methyl, ethyl, n-propyl, cyclopropyl, vinyl, ethynyl, fluorine, chlorine, bromine, C1-C3alkoxy, C1-C2-fluoroalkoxy, C1-C2alkoxy-C1-C3alkoxy- or C1fluoroalkoxy-C1-C3alkoxy-; and Y is O, S, S(O), S(O)2, N(C1-C2alkyl), N(C1-C2alkoxy), C(O), CR8R9 or —CR10R11CR12R13—; and G, R3, R4, R5 and R6 are as defined herein; wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.

Abstract: The invention provides a combination comprising compounds of formula (I) or salts thereof, and one or more therapeutic agents.

Abstract: In an inductively coupled power transmitter a force detector that detects the presence of a potential device by monitoring forces applied to a surface of the power transmitter and activates the inductively coupled power transmitter upon detection of a potential device. An inductively coupled power transmitter having a proximity detector that detects the presence and location of a potential device by monitoring the proximity of devices to a surface of the power transmitter and activates the inductively coupled power transmitter upon detection of a potential device. The transmitter preferably has one or more detection coils each having an area much greater than that of the transmitter coils for detecting the presence of a potential device.

Abstract: A computer-implemented method, computer program product, and computing system for defining at least a portion within a simulation modeling file for copying from an original location, thus defining an identified portion. A destination location is defined for the identified portion. A multi-threaded copying procedure is effectuated to copy the identified portion from the original location to the destination location, thus generating a copied portion of the simulation modeling file. The multi-threaded copying procedure utilizes at least two processing threads.

Abstract: The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.

Abstract: The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.

Abstract: In a method of controlling operation of a processing system, a host computer, a process tool and a component of an evacuation system, for example an abatement tool, are connected to a system bus. The abatement tool monitors signals transmitted on the system bus between the host computer and the process tool, and signals received directly from the process tool. The abatement tool uses information contained within the monitored signals to generate a signal for the process tool regarding an operating characteristic of the abatement tool. This signal is transmitted either directly or over the system bus to the process tool, which uses the generated signal to control an operating state of the process tool.

Abstract: A subsea manifold-riser system is redeployed from a first production location to a second production location. A manifold module is lowered to the ocean floor at the first production location using a marine riser as a running tool by adding threaded pipe sections to the upper end of the marine riser. The manifold module is raised from the ocean floor at the first production location for redeployment at the second production location using the marine riser as a retrieval tool by removing threaded pipe sections from the upper end of the marine riser.

Abstract: The present invention is directed to a polymorph of a compound and salts of a compound and polymorphs thereof, which compound is an inhibitor of kinase activity.