Patents by Inventor Nigel P. Beard
Nigel P. Beard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10739307Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: GrantFiled: January 25, 2019Date of Patent: August 11, 2020Assignee: APPLIED BIOSYSTEMS, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Patent number: 10638927Abstract: Described herein are customized, intelligent outerwear created through additive manufacturing and integrated with a plurality of sensors, actuators and other electronics to monitor user activity and provide various diagnostic and therapeutic capabilities. The outerwear is additively manufactured using a three-dimensional (“3D”) printer to provide for dynamic configurations of the sensors, actuators and other electronics depending on the specific needs of an individual. In addition to sensors for tracking motion, resistance, temperature and temporal features, the actuators may include piezoelectric components and microfluidic components to provide for therapeutic treatments, medical treatments and accident avoidance features. The combination of sensors and other electronics may also provide applications for monitoring overall health and growth.Type: GrantFiled: May 15, 2015Date of Patent: May 5, 2020Assignee: CASCA DESIGNS INC.Inventors: Lucy A. Beard, Nigel P. Beard
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Publication number: 20190293598Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: ApplicationFiled: January 25, 2019Publication date: September 26, 2019Inventors: Charles S. VANN, Debjyoti BANERJEE, Timothy G. GEISER, James C. NURSE, Nigel P. BEARD
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Patent number: 10241498Abstract: Described herein is customized outerwear created through additive manufacturing to provide for a plurality of materials, patterns and shapes that are customized for a particular user. The outerwear is designed through the use of a three-dimensional (“3D”) model of a body part, such as an additively-manufactured shoe for a foot. The 3D model is analyzed to provide detailed information on the anatomical features of the body part, which aids in the selection of specific materials, patterns of materials and shapes that are integrated into the design of the customized outerwear. The design is then loaded into an additive manufacturing machine, such as a 3D printer, for inexpensive and rapid manufacturing.Type: GrantFiled: May 15, 2015Date of Patent: March 26, 2019Inventors: Lucy A. Beard, Nigel P. Beard
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Patent number: 10215730Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: GrantFiled: June 5, 2017Date of Patent: February 26, 2019Assignee: APPLIED BIOSYSTEMS, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Patent number: 10016941Abstract: Systems and methods of capturing images of body parts to create a three-dimensional (“3D”) model for designing customized outerwear are provided. Images of a body part are captured by an image sensor on a camera or mobile device from various angles, after which they are combined using an algorithm to generate a point cloud map of the image data which is used to generate a 3D representation of the body part. The 3D model of the body part can then be analyzed to determine any unique features of the body part that will require customized outerwear, such as pressure points, deformities, etc. The 3D model can thus be used to develop highly-customized outerwear for an individual. The 3D model is a digital file which can then be utilized by software to design the customized outerwear and request that the outerwear be manufactured, for example by additive manufacturing on a 3D printer.Type: GrantFiled: May 15, 2015Date of Patent: July 10, 2018Assignee: FEETZ, INC.Inventors: Lucy A. Beard, Nigel P. Beard
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Publication number: 20180128778Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: ApplicationFiled: June 5, 2017Publication date: May 10, 2018Inventors: Charles S. VANN, Debjyoti BANERJEE, Timothy G. GEISER, James C. NURSE, Nigel P. BEARD
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Publication number: 20180016624Abstract: Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.Type: ApplicationFiled: July 24, 2017Publication date: January 18, 2018Inventors: Min YUE, David M. LIU, Joy ROY, Yuh-Min CHIANG, Joon Mo YANG, Dennis LEHTO, Charles S. VANN, Nigel P. BEARD, Ian A. HARDING, John R. Van Camp, Alexander DROMARETSKY, Sergey V. ERMAKOV, Mark F. OLDHAM, Maryam SHARIATI, Umberto ULMANELLA
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Patent number: 9714444Abstract: Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.Type: GrantFiled: December 2, 2013Date of Patent: July 25, 2017Assignee: APPLIED BIOSYSTEMS, LLCInventors: Min Yue, David M. Liu, Joy Roy, Yuh-Min Chiang, Joon Mo Yang, Dennis Lehto, Charles S. Vann, Nigel P. Beard, Ian A. Harding, John R. Van Camp, Alexander Dromaretsky, Sergey V. Ermakov, Mark F. Oldham, Maryam Shariati, Umberto Ulmanella
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Patent number: 9671365Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: GrantFiled: August 4, 2015Date of Patent: June 6, 2017Assignee: Applied Biosystems, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Publication number: 20150338372Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: ApplicationFiled: August 4, 2015Publication date: November 26, 2015Inventors: Charles S. VANN, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Publication number: 20150338373Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: ApplicationFiled: August 4, 2015Publication date: November 26, 2015Inventors: Charles S. VANN, Debjyoti BANERJEE, Timothy G. GEISER, James C. NURSE, Nigel P. BEARD
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Patent number: 9132400Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: GrantFiled: September 8, 2014Date of Patent: September 15, 2015Assignee: Applied Biosystems, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Patent number: 9126169Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: GrantFiled: September 5, 2014Date of Patent: September 8, 2015Assignee: Applied Biosystems, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Publication number: 20150238919Abstract: Exemplary embodiments provide microfluidic devices and methods for their use. The microfluidic device can include an array of M×N reaction sites formed by intersecting a first and second plurality of fluid channels of a flow layer. The flow layer can have a matrix design and/or a blind channel design to analyze a large number of samples under a limited number of conditions. The microfluidic device can also include a control layer including a valve system for regulating solution flow through fluid channels. In addition, by aligning the control layer with the fluid channels, the detection of the microfluidic devices, e.g., optical signal collection, can be improved by piping lights to/from the reaction sites. In an exemplary embodiment, guard channels can be included in the microfluidic device for thermal cycling and/or reducing evaporation from the reaction sites.Type: ApplicationFiled: January 30, 2015Publication date: August 27, 2015Inventors: Mark F. OLDHAM, Dar BAHATT, Kenneth J. LIVAK, Jason E. BABCOKE, H. Pin KAO, Stephen J. GUNSTREAM, Kevin S. BODNER, Douglas P. GREINER, Nigel P. BEARD
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Publication number: 20150219534Abstract: A device according to various embodiments can include a first chamber and a second chamber configured to contain at least one biological sample. A triturating element is interdisposed between the first chamber and the second chamber and provides fluid communication between the first chamber and the second chamber.Type: ApplicationFiled: February 4, 2015Publication date: August 6, 2015Inventors: Nigel P. Beard, James C. Nurse
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Patent number: 9061262Abstract: A device having a first substrate and a second substrate separated from the first substrate to form a volume between the first and second substrates, electrodes disposed on the first and second substrates and facing the volume, each substrate comprising at least one electrode, and a first insulating layer disposed on the first substrate and a second insulating layer disposed on the second substrate to separate the electrodes from the volume.Type: GrantFiled: April 28, 2014Date of Patent: June 23, 2015Assignee: Applied Biosystems, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Patent number: 9044724Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: GrantFiled: May 10, 2013Date of Patent: June 2, 2015Assignee: Applied Biosystems, LLCInventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard
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Patent number: 8945481Abstract: Exemplary embodiments provide microfludic devices and methods for their use. The microfluidic device can include an array of M×N reaction sites formed by intersecting a first and second plurality of fluid channels of a flow layer. The flow layer can have a matrix design and/or a blind channel design to analyze a large number of samples under a limited number of conditions. The microfluidic device can also include a control layer including a valve system for regulating solution flow through fluid channels. In addition, by aligning the control layer with the fluid channels, the detection of the microfluidic devices, e.g., optical signal collection, can be improved by piping lights to/from the reaction sites. In an exemplary embodiment, guard channels can be included in the microfluidic device for thermal cycling and/or reducing evaporation from the reaction sites.Type: GrantFiled: June 24, 2008Date of Patent: February 3, 2015Assignee: Applied Biosystems, LLCInventors: Mark F. Oldham, Kenneth J. Livak, Jason E. Babcoke, H. Pin Kao, Stephen J. Gunstream, Kevin S. Bodner, Douglas P. Greiner, Nigel P. Beard, Dar Bahatt
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Publication number: 20150008129Abstract: A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.Type: ApplicationFiled: September 8, 2014Publication date: January 8, 2015Inventors: Charles S. Vann, Debjyoti Banerjee, Timothy G. Geiser, James C. Nurse, Nigel P. Beard