Patents by Inventor Nigel Philip Taylor

Nigel Philip Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing the calcium salt of rosuvastatin
    Patent number: 7842807
    Abstract: An improved process for manufacture of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: November 30, 2010
    Assignee: AstraZeneca UK Limited
    Inventors: John Horbury, Nigel Philip Taylor
  • Process for Preparing the Calcium Salt of Rosuvastatin
    Publication number: 20090286819
    Abstract: An improved process for manufacture of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.
    Type: Application
    Filed: February 13, 2009
    Publication date: November 19, 2009
    Applicant: AstraZeneca AB
    Inventors: John Horbury, Nigel Philip Taylor
  • Process for preparing the calcium salt of rosuvastatin
    Patent number: 7511140
    Abstract: An improved process for manufacture of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl)(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: March 31, 2009
    Assignee: AstraZeneca AB
    Inventors: John Horbury, Nigel Philip Taylor
  • Crystalline salts of 7-?4-(4-fluorophenyl) -6-isopropyl-2-?methyl (methylsulfonyl) amino!pyrimidin-5-yl!- (3R, 5S) -3, 5-dihydroxyhept-6-enoic acid
    Patent number: 7129352
    Abstract: The invention relates to crystalline salts of the compound (E)-7-[4-(4-fluorophenyl)isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid of formula (I), as well as processes for their manufacture, pharmaceutical compositions containing them, and their uses
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: October 31, 2006
    Assignees: AstraZeneca AB, Shionogi & Co., Ltd.
    Inventors: Nigel Philip Taylor, Tetsuo Okada
  • Crystalline salts of 7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3r,5s)-3,5-dihydroxyhept-6-enoic acid
    Patent number: 6841554
    Abstract: The invention relates to crystalline salts of the compound (E)-7-[4-(4-fluorophenyl)-6-iso-propyl-2-[methyl(methyl-sulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid of formula (I), as well as processes for their manufacture, pharmaceutical compositions containing them, and their uses
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: January 11, 2005
    Assignees: AstraZeneca AB, Shionogi & Co., Ltd.
    Inventors: Nigel Philip Taylor, Tetsuo Okada
  • Crystalline salts of 7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3r,5s)-3,5-dihydroxyhept-6-enoic acid
    Publication number: 20030045718
    Abstract: The invention relates to crystalline salts of the compound (E)-7-[4-(4-fluorophenyl)-6-iso-propyl-2-[methyl(methyl-sulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid of formula (I),as well as processes for their manufacture, pharmaceutical compositions containing them, and their uses.
    Type: Application
    Filed: August 15, 2002
    Publication date: March 6, 2003
    Inventors: Nigel Philip Taylor, Tetsuo Okada
  • Process for preparing an antifungal azole with hydrazino and amidrazone intermediates
    Patent number: 5861516
    Abstract: A process for preparing an antifungal azole compound of formula (I) by reacting an epoxide with hydrazine to from a hydrazino compound which is subsequently reacted with an iminoether. The amidrazone product is subsequently reacted with an orthoformate to provide the antifungal azole. The azole, known as ZD0870, shows good activity against human fungal infections including Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: January 19, 1999
    Assignee: Zeneca Limited
    Inventors: Elwyn Peter Davies, John David Pittam, Keith Blakeney Mallion, Nigel Philip Taylor