Abstract: The disclosure relates to DNA polymerase delta subunit 1 (POLD1) polypeptides that mediate resistance to geminiviruses in plants. Also disclosed are plants comprising polynucleotides encoding the POLD1 polypeptides along with related methods of using polynucleotides that encode the POLD1 polypeptides to enhance resistance of a plant to infection by a geminivirus.

Abstract: The present disclosure is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The disclosure discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The disclosure also discloses methods and compositions for targeted genome editing in the pest in order to achieve a reduction in pest infestation through disruption of protein activity. The disclosure is also directed to methods for making transgenic plants that express the double stranded RNA molecules and targeted genome editing constructs for use in protecting plants from pest infestation.

Abstract: The present disclosure is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The disclosure discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The disclosure also discloses methods and compositions for targeted genome editing in the pest in order to achieve a reduction in pest infestation through disruption of protein activity. The disclosure is also directed to methods for making transgenic plants that express the double stranded RNA molecules and targeted genome editing constructs for use in protecting plants from pest infestation.

Abstract: This document provides methods and materials related to plants (e.g., nontransgenic plants) that are tolerant to glyphosate-based herbicides. For example, glyphosate tolerant plants can have an altered expression profile (e.g., increased expression levels) of a 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) gene (e.g., a modified EPSPS gene).

Abstract: Two new polymorphic forms of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid tris(hydroxymethyl)methylammonium salt (1), processes for making them and their use in the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis are described.

Abstract: A tert-butylamine salt, a piperazine salt, a choline salt, a tris(hydroxymethyl)methylamine salt, a lysine salt or an adamantylamine salt of (?)-2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]propanoic acid processes for their preparation, their use in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance and other manifestations of the metabolic syndrome, and pharmaceutical compositions containing them.

Abstract: A method and apparatus is provided for obtaining status information concerning an optical transmission path. The method begins by generating a COTDR probe signal having a prescribed wavelength and transmitting optical traffic signals and the COTDR probe signal over an optical transmission path having a length corresponding to those used in regional undersea market applications. The prescribed wavelength of the COTDR probe signal is separated from wavelengths at which the optical traffic signals are located by a distance at least equal to a predetermined guard band. A backscattered and/or reflected portion of the COTDR probe signal in which status information concerning the optical path is embodied is received over the optical path. The backscattered and/or reflected portion of the COTDR probe signal is detected to obtain the status information.

Abstract: An improved process for manufacture of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl)(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.

Abstract: The invention relates to crystalline salts of the compound (E)-7-[4-(4-fluorophenyl)isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid of formula (I), as well as processes for their manufacture, pharmaceutical compositions containing them, and their uses.

Abstract: The present invention provides a lid for a beverage cup. The lid has a generally annular side wall, a rib depending from the side wall, and a top wall extending radially inward from the side wall. The lid further includes a central region positioned radially inward of the top wall. The central region has a well with a notched portion. The lid also includes a projection extending from a portion of the side wall. A living hinge formed by a line of weakness at the base of the projection permits the projection to pivot between an open position and a closed position. The central region has a shoulder portion that engages the tip of the projection to secure the projection in the open position.

Abstract: A branching unit is provided for interconnecting at least three undersea optical transmission cables. The branching unit includes first, second and third ports for receiving first, second and third undersea optical transmission cables, respectively. The first and second cables each include an electrical power conductor and a plurality of first optical fibers. The third cable is electrically unpowered and includes at least one drop optical fiber and at least one add optical fiber. An electrical power conductor segment is provided for electrically coupling the conductor in the first cable received in the first port to the conductor in the second cable received in the second port. A first optical fiber segment optically couples a first of the plurality of first optical fibers in one of the first or second cables to the drop optical fiber of the third cable.

Abstract: A user configurable control device is particularly suitable for household devices such as remote control transmitters. A variety of function control elements in the form of keys are provided to the consumer who selects a desired set of the control elements. Each of the control elements has a unique pattern of projections molded into the bottom surface. These projections are in operative alignment with an array of membrane switches disposed on a switching substrate within the control device. The control device includes a front panel that is perforated with a pattern of slots. Each of the control elements has a pair of projecting tabs that look the element onto the control panel so that it is securely retained thereon, but may be released if desired. The projections on the bottom of the element extend through the slots in the front panel to the switching substrate below.

Abstract: A user configurable control device is particularly suitable for household devices such as remote control transmitters. A variety of function control elements in the form of keys are provided to the consumer who selects a desired set of the control elements. Each of the control elements has a unique pattern of projections molded into the bottom surface. These projections are in operative alignment with an array of membrane switches disposed on a switching substrate within the control device. The control device includes a front panel that is perforated with a pattern of slots. Each of the control elements has a pair of projecting tabs that lock the element onto the control panel so that it is securely retained thereon, but may be released if desired. The projections on the bottom of the element extend through the slots in the front panel to the switching substrate below.

Abstract: The gain of an optical amplifier is maintained constant by employing a portion of the amplified optical signal in a feedback loop. In one arrangement this is used to control the output of a pump signal source accordingly. The portion of the said signal corresponds to spontaneous emission (ASE) at a control wavelength or band of wavelengths different to the wavelength of the optical signal output. In the case of an erbium, for example, optical fibre amplifier the portion is preferably ASE at 980 nm, the amplified signal being at 1.535 .mu.m, i.e. completely different transitions in the amplifying medium are used for gain and ASE feedback in order to lessen requirements on the filter used to extract the portion for the feedback loop.