Abstract: A synthetic resin container including a mouthpiece sealed by a closure is to be used for medical drip infusion or the like. The closure has a tight-sealing synthetic resin stopper, and a leakage preventing rubber stopper for preventing liquid leakage when the closure is pierced by a needle or the like. The mouthpiece of the synthetic resin container is sealed by the closure according to a method including providing a concave portion and/or a convex portion having a cross-section shaped in a wedge or the like at one or both of the upper portions of the mouthpiece and the tight-sealing synthetic resin stopper in order to impart provided thermal conductivity. The synthetic resin stopper is inserted into the mouthpiece and the rubber stopper is inserted into the synthetic resin stopper. The upper portions of the mouthpiece and the synthetic resin stopper are covered with a metallic mouthpiece forming cap.

Abstract: There is disclosed a simply constructed apparatus for and a ready method of blockading a mouthpiece of a transfusion synthetic resin container used for medical drip infusion. Based on the apparatus and the method thereof, insertion of an instillation needle can be facilitated, and there is no leakage of fluid. Besides, low costs of manufacture suffice, and high efficiency can be attained.