Abstract: In some embodiments, a sensor assembly for a continuous glucose monitoring system is provided that includes (1) a sensor carrier having a sensor unit receiving area and an electronics receiving area, the electronics receiving area including a substrate; (2) a sensor unit having a sterilized region, the sterilized region including at least a portion of a sensor and an introducer; and (3) electronics for the continuous glucose monitoring system. The sensor unit is positioned within the sensor unit receiving area of the sensor carrier and the electronics are positioned on the substrate within the electronics receiving area of the sensor carrier so as to form a sensor assembly having the sensor electrically connected to the substrate of the electronics receiving area while maintaining sterilization of the sterilized region of the sensor unit. Numerous other aspects are provided.

Abstract: In some embodiments, a sensor assembly for a continuous glucose monitoring system is provided that includes (1) a sensor carrier having a sensor unit receiving area and an electronics receiving area, the electronics receiving area including a substrate; (2) a sensor unit having a sterilized region, the sterilized region including at least a portion of a sensor and an introducer; and (3) electronics for the continuous glucose monitoring system. The sensor unit is positioned within the sensor unit receiving area of the sensor carrier and the electronics are positioned on the substrate within the electronics receiving area of the sensor carrier so as to form a sensor assembly having the sensor electrically connected to the substrate of the electronics receiving area while maintaining sterilization of the sterilized region of the sensor unit. Numerous other aspects are provided.

Abstract: In some embodiments, a sensor assembly for a continuous glucose monitoring system is provided that includes (1) a sensor carrier having a sensor unit receiving area and an electronics receiving area, the electronics receiving area including a substrate; (2) a sensor unit having a sterilized region, the sterilized region including at least a portion of a sensor and an introducer; and (3) electronics for the continuous glucose monitoring system. The sensor unit is positioned within the sensor unit receiving area of the sensor carrier and the electronics are positioned on the substrate within the electronics receiving area of the sensor carrier so as to form a sensor assembly having the sensor electrically connected to the substrate of the electronics receiving area while maintaining sterilization of the sterilized region of the sensor unit. Numerous other aspects are provided.

Abstract: An adapter assembly includes an elongated body, a switch, a sensor link, and an annular member. The elongated body includes a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit. The switch is configured to be toggled in response to the surgical loading unit being coupled to the distal portion of the adapter assembly. The sensor link is disposed within the distal portion of the adapter assembly and biased toward a distal position. The sensor link is longitudinally movable between a proximal position and the distal position. The annular member is disposed within the distal portion and is rotatable between a first orientation, in which the annular member prevents distal movement of the sensor link, and a second orientation, in which the sensor link moves distally to toggle the switch.

Abstract: An elongated member is used to create tension to move teeth en masse to correct Class II and Class III malocclusions. The elongated member has a constant force spring that, when stretched, provides tension along the elongated member. A mesial end of the elongated member is attached to a bridge assembly which is attached to a row of teeth, and a distal end of the elongated member is attached to an anchor. The spring member provides a constant tension which moves the bridge assembly, and hence the row of teeth, a precalibrated distance.

Abstract: Embodiments provide systems, methods, and apparatus for a medication delivery device. The device includes a dose selector for selecting an amount of medication to deliver; a first capacitive sensor adjacent the dose selector and operative to detect linear displacement of the dose selector during medication delivery; a screw coupled to the dose selector; a second capacitive sensor adjacent the screw and operative to detect linear displacement of the screw during medication delivery; and a processor coupled to the first and second capacitive sensors and operative to determine an amount of medication actually delivered by the medication delivery device. Numerous other aspects are provided.

Abstract: An adapter assembly selectively interconnects a surgical end effector that is configured to perform at least a pair of functions and a surgical device that is configured to actuate the end effector. The end effector includes a first axially translatable drive member and a second axially translatable drive member. The surgical device includes a first rotatable drive shaft and a second rotatable drive shaft.

Abstract: An adapter assembly includes an elongated body, a switch, a sensor link, and an annular member. The elongated body includes a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit. The switch is configured to be toggled in response to the surgical loading unit being coupled to the distal portion of the adapter assembly. The sensor link is disposed within the distal portion of the adapter assembly and biased toward a distal position. The sensor link is longitudinally movable between a proximal position and the distal position. The annular member is disposed within the distal portion and is rotatable between a first orientation, in which the annular member prevents distal movement of the sensor link, and a second orientation, in which the sensor link moves distally to toggle the switch.

Abstract: An adapter assembly selectively interconnects a surgical end effector that is configured to perform at least a pair of functions and a surgical device that is configured to actuate the end effector. The end effector includes a first axially translatable drive member and a second axially translatable drive member. The surgical device includes a first rotatable drive shaft and a second rotatable drive shaft.

Abstract: An adapter assembly includes an elongated body, a switch, a sensor link, and an annular member. The elongated body includes a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit. The switch is configured to be toggled in response to the surgical loading unit being coupled to the distal portion of the adapter assembly. The sensor link is disposed within the distal portion of the adapter assembly and biased toward a distal position. The sensor link is longitudinally movable between a proximal position and the distal position. The annular member is disposed within the distal portion and is rotatable between a first orientation, in which the annular member prevents distal movement of the sensor link, and a second orientation, in which the sensor link moves distally to toggle the switch.

Abstract: An adapter assembly includes an elongated body, a switch, a sensor link, and an annular member. The elongated body includes a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit. The switch is configured to be toggled in response to the surgical loading unit being coupled to the distal portion of the adapter assembly. The sensor link is disposed within the distal portion of the adapter assembly and biased toward a distal position. The sensor link is longitudinally movable between a proximal position and the distal position. The annular member is disposed within the distal portion and is rotatable between a first orientation, in which the annular member prevents distal movement of the sensor link, and a second orientation, in which the sensor link moves distally to toggle the switch.

Abstract: Embodiments provide systems, methods, and apparatus for a medication delivery device. The device includes a dose selector for selecting an amount of medication to deliver; a first capacitive sensor adjacent the dose selector and operative to detect linear displacement of the dose selector during medication delivery; a screw coupled to the dose selector; a second capacitive sensor adjacent the screw and operative to detect linear displacement of the screw during medication delivery; and a processor coupled to the first and second capacitive sensors and operative to determine an amount of medication actually delivered by the medication delivery device. Numerous other aspects are provided.

Abstract: In some embodiments, a sensor assembly for a continuous glucose monitoring system is provided that includes (1) a sensor carrier having a sensor unit receiving area and an electronics receiving area, the electronics receiving area including a substrate; (2) a sensor unit having a sterilized region, the sterilized region including at least a portion of a sensor and an introducer; and (3) electronics for the continuous glucose monitoring system. The sensor unit is positioned within the sensor unit receiving area of the sensor carrier and the electronics are positioned on the substrate within the electronics receiving area of the sensor carrier so as to form a sensor assembly having the sensor electrically connected to the substrate of the electronics receiving area while maintaining sterilization of the sterilized region of the sensor unit. Numerous other aspects are provided.

Abstract: An adapter assembly includes an elongated body, a switch, a sensor link, and an annular member. The elongated body includes a proximal portion configured to couple to a handle assembly and a distal portion configured to couple to a surgical loading unit. The switch is configured to be toggled in response to the surgical loading unit being coupled to the distal portion of the adapter assembly. The sensor link is disposed within the distal portion of the adapter assembly and biased toward a distal position. The sensor link is longitudinally movable between a proximal position and the distal position. The annular member is disposed within the distal portion and is rotatable between a first orientation, in which the annular member prevents distal movement of the sensor link, and a second orientation, in which the sensor link moves distally to toggle the switch.

Abstract: Described are single-use dispensing devices with a dry chamber containing lyophilized material, a wet chamber containing reconstituting solution, a breaking chamber positioned between and attached to the dry chamber and a first end of the wet chamber. The breaking chamber includes a leak-proof frangible seal that prevent mixing of the lyophilized material and the reconstituting solution until the frangible seal is broken.

Abstract: An adapter assembly selectively interconnects a surgical end effector that is configured to perform at least a pair of functions and a surgical device that is configured to actuate the end effector. The end effector includes a first axially translatable drive member and a second axially translatable drive member. The surgical device includes a first rotatable drive shaft and a second rotatable drive shaft.

Abstract: A surgical fastening apparatus includes a fastener retaining frame having a first annular portion having a plurality of retainers circumferentially disposed thereon and a second annular portion having a plurality of circumferentially arranged perforations. The fastener retaining frame is detachably secured to a supporting structure. After the plurality of surgical fasteners has been mated with the plurality of retainers, an annular blade severs the perforations.

Abstract: Adapter assemblies are provided for selectively interconnecting a surgical end effector that is configured to perform at least a pair of functions and a surgical device that is configured to actuate the end effector, wherein the end effector includes a first axially translatable drive member and a second axially translatable drive member, and wherein the surgical device includes a first rotatable drive shaft and a second rotatable drive shaft.

Abstract: A surgical stapling instrument comprising a handle assembly having a proximal end, an elongated body portion extending distally from the handle assembly, a head portion disposed adjacent a distal portion of the elongated body portion and including an anvil assembly and a shell assembly. The shell assembly includes a shell and a staple guide housing a plurality of staples. A flexible engagement structure attaches the staple guide to the shell.