Patents by Inventor Nihmat Morjana

Nihmat Morjana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF
    Publication number: 20220049018
    Abstract: Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disclosed are methods of reducing naloxone or naltrexone interference in opiate assays using the antibodies.
    Type: Application
    Filed: January 30, 2020
    Publication date: February 17, 2022
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Manoj Sharma, Tatiana Lebedeva, Tatiana Mareeva, Yuriy Smirnov, Bogdan Draghici, Zhu Teng, Yi Feng Zheng, Heungyeung Yau, Nihmat Morjana, William Bedzyk, Allison Dominowski
  • Preparation of multi-hapten mutant G6PDH conjugates and their use for detection of multiple analytes
    Patent number: 10450555
    Abstract: The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6PDH conjugate. Both thiol and amine functional groups on G6PDH are utilized for immobilization of different haptens.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: October 22, 2019
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Yi Feng Zheng, Yali Yang, Linda Hudson, Nihmat Morjana
  • PREPARATION OF MULTI-HAPTEN MUTANT G6PDH CONJUGATES AND THEIR USE FOR DETECTION OF MULTIPLE ANALYTES
    Publication number: 20190055538
    Abstract: The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6PDH conjugate. Both thiol and amine functional groups on G6PDH are utilized for immobilization of different haptens.
    Type: Application
    Filed: November 2, 2018
    Publication date: February 21, 2019
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Yi Feng Zheng, Yali Yang, Linda Hudson, Nihmat Morjana
  • PREPARATION OF MULTI-HAPTEN MUTANT G6PDH CONJUGATES AND THEIR USE FOR DETECTION OF MULTIPLE ANALYTES
    Publication number: 20160312208
    Abstract: The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6PDH conjugate. Both thiol and amine functional groups on G6PDH are utilized for immobilization of different haptens.
    Type: Application
    Filed: December 10, 2014
    Publication date: October 27, 2016
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Yi Feng Zheng, Yali Yang, Linda Hudson, Nihmat Morjana
  • Covalently coupled troponin complexes
    Patent number: 6268481
    Abstract: Stabilized compositions for use in clinical assays for troponin are disclosed. The compositions are covalently coupled complexes of cardiac troponin I, cardiac troponin T, and/or troponin C.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: July 31, 2001
    Assignee: Medical Analysis Systems, Inc.
    Inventor: Nihmat Morjana
  • Troponin I forms and use of the same
    Patent number: 6248869
    Abstract: The present invention relates to an isolated fragment of human cardiac troponin I (TnI) comprising the following sequence X-A-B-Y wherein X comprises any of amino acid residues 1-27 of SEQ ID NO: 2; A comprises amino acid residues 28-69 of SEQ ID NO: 2; B comprises amino acid residues 70-90 of SEQ ID NO: 2; and Y comprises any of amino acid residues 91-170 of SEQ ID NO: 2. The present invention further relates to fragments of TnI wherein the fragment has a greater immunologic reactivity than intact cTnI when the fragment and intact cTnI are reacted with a monoclonal antibody, which has an epitopic site on the fragment.
    Type: Grant
    Filed: May 29, 1997
    Date of Patent: June 19, 2001
    Assignee: Medical Analysis Systems, Inc.
    Inventors: Nihmat A. Morjana, Angela M. Puia