Patents by Inventor Nii Patterson
Nii Patterson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220235365Abstract: A transgenic land plant that expresses a polyhydroxy alkanoate synthase seed specifically, with cytosolic localization is disclosed. The plant includes a nucleic acid encoding the polyhydroxy alkanoate synthase and a seed-specific promoter operably linked to the nucleic acid. The seed-specific promoter drives expression of the polyhydroxy alkanoate synthase in cytosol of cells of seeds of the plant. The polyhydroxy alkanoate synthase includes a catalytic domain. The polyhydroxy alkanoate synthase does not include any sequence positioned to mediate translocation of the catalytic domain across any membrane of the cells, thereby resulting in the polyhydroxy alkanoate synthase being expressed seed specifically, with cytosolic localization.Type: ApplicationFiled: June 9, 2020Publication date: July 28, 2022Inventors: Meghna MALIK, Nii PATTERSON, Jihong TANG, Matthew MARTINO, Nirmala SHARMA, Oliver P. PEOPLES, Kristi D. SNELL, Frank Anthony SKRALY
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Patent number: 9181559Abstract: Transgenic plants, plant material, plant cells, and genetic constructs for synthesis of biopolymers, for example polyhydroxyalkanoates (“PHA”) are provided. In one embodiment, the transgenic plants synthesize polyhydroxybutyrate (“PHB”). In one embodiment the transgenic plant encodes siRNA for one or more of the genes encoding enzymes for producing PHA. In a more preferred embodiment, the siRNA expression is under the control of an inducible regulatory element. In another embodiment, the transgenic plant contains transgenes that encode expression enzymes that will degrade the polymer. In a preferred embodiment, the expression of these enzymes is under the control of a germination specific, inducible, or minimal promoter. In another embodiment, the transgenic plant contains transgenes encoding enzymes that increase carbon flow for polymer synthesis. In a preferred embodiment, these transgenes encode enzymes that increase carbon flow in the Calvin Cycle.Type: GrantFiled: September 15, 2010Date of Patent: November 10, 2015Assignee: Metabolix, Inc.Inventors: Nii Patterson, Jihong Tang, Jixiang Han, Venkata Tavva, Andrew Hertig, Zhigang Zhang, Thomas Martin Ramseier, Karen Bohmert-Tatarev, Oliver P. Peoples, Kristi D. Snell
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Patent number: 8487159Abstract: Transgenic plants, plant material, and plant cells for synthesis of polyhydroxyalkanoates, preferably poly(3-hydroxybutyrate) (also referred to a as PHB) are provided. Preferred plants that can be genetically engineered to produce PHB include plants that do not normally produce storage products such as oils and carbohydrates, and plants that have a C4 NAD-malic enzyme photosynthetic pathway. Such plants also advantageously produce lignocellulosic biomass that can be converted into biofuels. An exemplary plant that can be genetically engineered to produce PHB and produce lignocellulosic biomass is switchgrass, Panicum virgatum L. A preferred cultivar of switchgrass is Alamo. Other suitable cultivars of switchgrass include but are not limited to Blackwell, Kanlow, Nebraska 28, Pathfinder, Cave-in-Rock, Shelter and Trailblazer.Type: GrantFiled: April 28, 2009Date of Patent: July 16, 2013Assignee: Metabolix, Inc.Inventors: Mariya N. Somleva, Kristi D. Snell, Julie Beaulieu, Oliver P. Peoples, Bradley Garrison, Nii Patterson
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Publication number: 20120180162Abstract: Transgenic plants, plant material, plant cells, and genetic constructs for synthesis of biopolymers, for example polyhydroxyalkanoates (“PHA”) are provided. In one embodiment, the transgenic plants synthesize polyhydroxybutyrate (“PHB”). In one embodiment the transgenic plant encodes siRNA for one or more of the genes encoding enzymes for producing PHA. In a more preferred embodiment, the siRNA expression is under the control of an inducible regulatory element. In another embodiment, the transgenic plant contains transgenes that encode expression enzymes that will degrade the polymer. In a preferred embodiment, the expression of these enzymes is under the control of a germination specific, inducible, or minimal promoter. In another embodiment, the transgenic plant contains transgenes encoding enzymes that increase carbon flow for polymer synthesis. In a preferred embodiment, these transgenes encode enzymes that increase carbon flow in the Calvin Cycle.Type: ApplicationFiled: September 15, 2010Publication date: July 12, 2012Applicant: METABOLIX, INC.Inventors: Nii Patterson, Jihong Tang, Jixiang Han, Venkata Tavva, Andrew Hertig, Zhigang Zhang, Thomas Martin Ramseier, Karen Bohmert-tatarev, Oliver P. peoples, Kristi D. Snell
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Publication number: 20120174253Abstract: Transgenic oilseed plants, plant material, plant cells, and genetic constructs for synthesis of polyhydroxyalkanoates (“PHA”) are provided. In a preferred embodiment, the transgenic oilseed plants synthesize (poly)3-hydroxybutyrate (“PHB”) in the seed. Genes utilized include phaA, phaB, phaC, all of which are known in the art. The genes can be introduced in the plant, plant tissue, or plant cell using conventional plant molecular biology techniques.Type: ApplicationFiled: September 15, 2010Publication date: July 5, 2012Inventors: Nii Patterson, Jihong Tang, Edgar Benjamin Cahoon, Jan G. Jaworski, Wenyu Yang, Oliver P. Peoples, Kristi D. Snell
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Publication number: 20120060413Abstract: Transgenic plants, transgenic plant material, and transgenic plant cells for the improved synthesis of polyhydroxyalkanoates, preferably poly(3-hydroxybutyrate) (also referred to as PHB), have been developed. In one embodiment, carbon flow is modulated to increase production of PHB. Preferred plants that can be genetically engineered to produce PHB include plants that produce a large amount of lignocellulosic biomass that can be converted into biofuels, such as switchgrass, Miscanthus, Sorghum, sugarcane, millets, Napier grass and other forage and turf grasses. An exemplary plant that can be genetically engineered to produce PHB and produces lignocellulosic biomass is switchgrass, Panicum virgatum L. A preferred cultivar of switchgrass is Alamo. Other suitable cultivars of switchgrass include, but are not limited to, Blackwell, Kanlow, Nebraska 28, Pathfinder, Cave-in-Rock, Shelter and Trailblazer.Type: ApplicationFiled: September 15, 2011Publication date: March 15, 2012Inventors: Mariya Somleva, Himani Chinnapen, Aminat Ali, Kristi D. Snell, Oliver P. Peoples, Nii Patterson, Jihong Tang, Karen Bohmert-Tatarev
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Publication number: 20110321190Abstract: Transgenic plants and methods of culturing them using sorbitol as a sole carbon source are provided. One embodiment provides a method and system for positively selecting transgenic plants carrying and expressing a gene of interest. The transgenic plants are engineered to express sorbitol dehydrogenase in an amount effective to allow the transgenic plant to grow using sorbitol as the sole carbon source. In a preferred embodiment, the plant to be transformed does not have endogenous sorbitol dehydrogenase activity. Representative plants that can be transformed, include but are not limited to members of the Brassica family, industrial oilseeds, Arabidopsis thaliana, algae, soybean, cottonseed, sunflower, palm, coconut, rice, safflower, peanut, mustards, silage corn, alfalfa, switchgrass, miscanthus, sorghum, tobacco, sugarcane and flax.Type: ApplicationFiled: September 1, 2011Publication date: December 29, 2011Inventors: Chakradhar Akula, Karen Bohmert-Tatarev, Nii Patterson, Kristi D. Snell
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Publication number: 20090271889Abstract: Transgenic plants, plant material, and plant cells for synthesis of polyhydroxyalkanoates, preferably poly(3-hydroxybutyrate) (also referred to a as PHB) are provided. Preferred plants that can be genetically engineered to produce PHB include plants that do not normally produce storage products such as oils and carbohydrates, and plants that have a C4 NAD-malic enzyme photosynthetic pathway. Such plants also advantageously produce lignocellulosic biomass that can be converted into biofuels. An exemplary plant that can be genetically engineered to produce PHB and produce lignocellulosic biomass is switchgrass, Panicum virgatum L. A preferred cultivar of switchgrass is Alamo. Other suitable cultivars of switchgrass include but are not limited to Blackwell, Kanlow, Nebraska 28, Pathfinder, Cave-in-Rock, Shelter and Trailblazer.Type: ApplicationFiled: April 28, 2009Publication date: October 29, 2009Inventors: Mariya N. Somleva, Kristi D. Snell, Julie Beaulieu, Oliver P. Peoples, Bradley Garrison, Nii Patterson
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Publication number: 20030233677Abstract: Methods and systems to modify fatty acid biosynthesis and oxidation in plants to make new polymers are provided. Two enzymes are essential: a hydratase such as D-specific enoyl-CoA hydratase, for example, the hydratase obtained from Aeromonas caviae, and a &bgr;-oxidation enzyme system. Some plants have a &bgr;-oxidation enzyme system which is sufficient to modify polymer synthesis when the plants are engineered to express the hydratase. Examples demonstrate production of polymer by expression of these enzymes in transgenic plants. Examples also demonstrate that modifications in fatty acid biosynthesis can be used to alter plant phenotypes, decreasing or eliminating seed production and increasing green plant biomass, as well as producing polyhydroxyalkanoates.Type: ApplicationFiled: May 28, 2003Publication date: December 18, 2003Applicant: Metabolix, Inc.Inventors: Oliver P. Peoples, Maurice Moloney, Nii Patterson, Kristi D. Snell
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Patent number: 6586658Abstract: Methods and systems to modify fatty acid biosynthesis and oxidation in plants to make new polymers are provided. Two enzymes are essential: a hydratase such as D-specific enoyl-CoA hydratase, for example, the hydratase obtained from Aeromonas caviae, and a &bgr;-oxidation enzyme system. Some plants have a &bgr;-oxidation enzyme system which is sufficient to modify polymer synthesis when the plants are engineered to express the hydratase. Examples demonstrate production of polymer by expression of these enzymes in transgenic plants. Examples also demonstrate that modifications in fatty acid biosynthesis can be used to alter plant phenotypes, decreasing or eliminating seed production and increasing green plant biomass, as well as producing polyhydroxyalkanoates.Type: GrantFiled: September 3, 1999Date of Patent: July 1, 2003Assignee: Metabolix, Inc.Inventors: Oliver P. Peoples, Maurice Moloney, Nii Patterson, Kristi D. Snell