Patents by Inventor Nik SAVAGE

Nik SAVAGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic AKR1C3 dependent KARS inhibitors
    Patent number: 11970497
    Abstract: The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1C3 dependent KARS inhibitor.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: April 30, 2024
    Assignee: Novartis AG
    Inventors: Chris Adair, Tracy Chen, Jian Ding, Christy Fryer, Yuko Isome, Marie-Helene Larraufie, Katsumasa Nakajima, Nik Savage, Ariel Sterling Twomey
  • TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS
    Publication number: 20220315582
    Abstract: The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1C3 dependent KARS inhibitor.
    Type: Application
    Filed: July 31, 2020
    Publication date: October 6, 2022
    Inventors: Chris ADAIR, Tracy CHEN, Jian DING, Christy FRYER, Yuko ISOME, Marie-Helene LARRAUFIE, Katsumasa NAKAJIMA, Nik SAVAGE, Ariel Sterling TWOMEY
  • BMP POTENTIATORS
    Publication number: 20190194227
    Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.
    Type: Application
    Filed: February 26, 2019
    Publication date: June 27, 2019
    Inventors: Jian DING, Marie-Helene LARRAUFIE, Deborah ROTHMAN, Nik SAVAGE, Shaowen WANG
  • BMP potentiators
    Patent number: 10259827
    Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: April 16, 2019
    Assignee: NOVARTIS AG
    Inventors: Jian Ding, Marie-Helene Larraufie, Deborah Rothman, Nik Savage, Shaowen Wang
  • BMP POTENTIATORS
    Publication number: 20180127436
    Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.
    Type: Application
    Filed: November 8, 2017
    Publication date: May 10, 2018
    Inventors: Jian DING, Marie-Helene LARRAUFIE, Deborah ROTHMAN, Nik SAVAGE, Shaowen WANG