Patents by Inventor Nikhil Dhoot

Nikhil Dhoot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20190022228
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 24, 2019
    Inventors: George Klein, Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Halina Levchik, Ehud Arbit, Nikhil Dhoot, Jamila Harris, Nai Fang Wang
  • FORMULATIONS FOR DELIVERING INSULIN
    Publication number: 20180338923
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 29, 2018
    Inventors: Halina LEVCHIK, Moses OYEWUMI, Shingai MAJURU, William E. BAY, Jun LIAO, Puchun LIU, Steven DINH, Nikhil DHOOT
  • Crystalline forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid
    Patent number: 9238074
    Abstract: The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: January 19, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Nikhil Dhoot, Steven Dinh, Shingai Majuru, William Elliott Bay, JoAnne P. Corvino, Doris C. O'Toole
  • FORMULATIONS FOR DELIVERING INSULIN
    Publication number: 20150190344
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Application
    Filed: January 5, 2015
    Publication date: July 9, 2015
    Inventors: Halina LEVCHIK, Moses Oyewumi, Shingai Majuru, William E. Bay, Jun Liao, Puchun Liu, Steven Dinh, Nikhil Dhoot
  • Acyclovir formulations
    Patent number: 8952017
    Abstract: The present invention relates to an acyclovir formulation having improved bioavailability resulting in better efficacy and/or requiring less frequent administration.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 10, 2015
    Assignee: Emisphere Technologies, Inc.
    Inventors: Amy C. Adams, Brahma N. Singh, Nikhil Dhoot, Shingai Majuru
  • Formulations for delivering insulin
    Patent number: 8927015
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: January 6, 2015
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Moses O. Oyewumi, Shingai Majuru, William Elliott Bay, Jun Liao, Puchun Liu, Steven Dinh, Nikhil Dhoot
  • CRYSTALLINE FORMS OF THE DI-SODIUM SALT OF N-(5-CHLOROSALICYLOYL)-8-AMINOCAPRYLIC ACID
    Publication number: 20130303444
    Abstract: The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.
    Type: Application
    Filed: April 5, 2013
    Publication date: November 14, 2013
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nikhil DHOOT, Steven DINH, Shingai MAJURU, William Elliott BAY, JoAnne P. CORVINO, Doris C. O'TOOLE
  • Acyclovir Formulations
    Publication number: 20130281471
    Abstract: The present invention relates to an acyclovir formulation having improved bioavailability resulting in better efficacy and/or requiring less frequent administration.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 24, 2013
    Inventors: Amy C. ADAMS, Brahma N. Singh, Nikhil Dhoot, Shingai Majuru
  • Crystalline forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid
    Patent number: 8431736
    Abstract: The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: April 30, 2013
    Assignee: Emisphere Technologies, Inc.
    Inventors: Nikhil Dhoot, Steven Dinh, Shingai Majuru, William Elliott Bay, JoAnne P. Corvino, Doris C. O'Toole
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20120189666
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: November 23, 2011
    Publication date: July 26, 2012
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nikhil Dhoot, Halina Levchik, Shingai Majuru, George Klein, Jamila Harris, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nai Fang Wang
  • CRYSTALLINE FORMS OF THE DI-SODIUM SALT OF N-(5-CHLOROSALICYLOYL)-8-AMINOCAPRYLIC ACID
    Publication number: 20120065128
    Abstract: The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.
    Type: Application
    Filed: August 11, 2011
    Publication date: March 15, 2012
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nikhil DHOOT, Steven Dinh, Shingai Majuru, William Elliott Bay, JoAnne P. Corvino, Doris C. O'Toole
  • Solid dosage form of wetted heparin
    Patent number: 8039018
    Abstract: The present invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wetted heparin. The inclusion of wetted heparin rather than un-wetted heparin in the solid pharmaceutical composition results in increased delivery of the heparin. Without being bound by any particular theory, applicants believe that because the polymer chain of the wetted heparin is already in an “open” form, while un-wetted heparin is not, less of the wetted heparin is broken down in the gastrointestinal tract and is more readily absorbed in the stomach.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: October 18, 2011
    Assignee: Emisphere Technologies, Inc.
    Inventors: Shingai Majuru, Brahma Singh, Nikhil Dhoot
  • Crystalline forms of the di-sodium salt of N-(5-Chlorosalicyloyl)-8-aminocaprylic acid
    Patent number: 8026392
    Abstract: The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.
    Type: Grant
    Filed: September 18, 2006
    Date of Patent: September 27, 2011
    Assignee: Emisphere Technologies, Inc.
    Inventors: Nikhil Dhoot, Steven Dinh, Shingai Majuru, William Elliott Bay, JoAnne P. Corvino, Doris C. O'Toole
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20100055194
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 4, 2010
    Applicant: Emisphere Technologies, Inc.
    Inventors: Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nikhil Dhoot, Halina Levchik, George Klein, Jamila Harris, Nai Fang Wang
  • ISOLATED NANOCAPSULE POPULATIONS AND SURFACTANT-STABILIZED MICROCAPSULES AND NANOCAPSULES FOR DIAGNOSTIC IMAGING AND DRUG DELIVERY AND METHODS FOR THEIR PRODUCTION
    Publication number: 20080279783
    Abstract: A method for producing surfactant-stabilized microcapsules or nanocapsules including the steps of (a) preparing a suspension comprising a non-ionic sorbitan detergent and a salt in phosphate buffered saline; (b) adding to the suspension a nonionic polyoxyethylenesorbitan detergent to produce a solution; (c) heating while stirring the solution of step (b) to 55±5° C. and maintaining the temperature of the solution at 55±5° C. for several minutes; (d) allowing the solution to cool to room temperature; (e) autoclaving the solution; (f) creating surfactant-stabilized microbubbles and nanobubbles in the solution; and (g) collecting surfactant-stabilized nanocapsules and microcapsules formed from the microbubbles and nanobubbles.
    Type: Application
    Filed: September 4, 2007
    Publication date: November 13, 2008
    Applicant: Drexel University
    Inventors: Margaret A. Wheatley, Brian E. Oeffinger, Nikhil Dhoot, Justin Lathia
  • Crystalline forms of the Di-Sodium Salt of N-(5-Chlorosalicyloyl)-8-Aminocaprylic Acid
    Publication number: 20080269108
    Abstract: The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same.
    Type: Application
    Filed: September 18, 2006
    Publication date: October 30, 2008
    Applicant: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Nikhil Dhoot, Steven Dinh, Shingai Majuru, William Elliott Bay, JoAnne P. Corvino, Doris C. O'Toole
  • Gastric Retention and Controlled Release Delivery System
    Publication number: 20080153779
    Abstract: The present invention provice a device (FIG. 3) for providing communication through power lines (FIG. 2) comprised of multiple conductors by transmitting the data signals through a plurality of the conductors. One embodiment of the present invention comprises a transmit circuit communicatively coupled to a first conductor for applying the first voltage representing the data to the first energized conductor; the transmit circuit communicatively coupled to a second conductor for applying the second voltage representing the data to the second energized conductor; wherein the second voltage signal is opposite in polarity of the first voltage.
    Type: Application
    Filed: February 1, 2006
    Publication date: June 26, 2008
    Inventors: Jun Liao, Puchun Liu, Steven Dinh, Brahma Singh, Shingai Majuru, Prateek N. Bhargava, Nikhil Dhoot
  • Compositions For Delivering Acyclovir
    Publication number: 20080132527
    Abstract: The present invention relates to an acyclovir formulation having improved bioavailability resulting in better efficacy and/or requiring less frequent administration.
    Type: Application
    Filed: May 19, 2005
    Publication date: June 5, 2008
    Applicant: Emisphere Technologies, Inc.
    Inventors: Amy C. Adams, Brahma N. Singh, Nikhil Dhoot, Shingai Majuru
  • Solid Dosage Form of Wetted Heparin
    Publication number: 20070224262
    Abstract: The present invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wetted heparin. The inclusion of wetted heparin rather than un-wetted heparin in the solid pharmaceutical composition results in increased delivery of the heparin. Without being bound by any particular theory, applicants believe that because the polymer chain of the wetted heparin is already in an “open” form, while un-wetted heparin is not, less of the wetted heparin is broken down in the gastrointestinal tract and is more readily absorbed in the stomach.
    Type: Application
    Filed: May 6, 2005
    Publication date: September 27, 2007
    Inventors: Shingai Majuru, Brahma Singh, Nikhil Dhoot
  • Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
    Publication number: 20060078623
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: August 15, 2005
    Publication date: April 13, 2006
    Applicant: Emisphere Technologies, Inc.
    Inventors: Nikhil Dhoot, Halina Levchik, Shingai Majuru, George Klein, Jamila Harris, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Ehud Arbit, Nai Wang