Patents by Inventor Nikit Patel

Nikit Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for control of gene expression
    Patent number: 11781149
    Abstract: Embodiments disclosed herein provide artificial expression systems comprising multivalent transcription factor complexes for cooperative transcription factor assembly and modulating gene expression. More specifically, engineered synthetic transcription factors are recruited and structurally organized on synthetic gene circuits using molecular clamps, where the strength of intra-complex interactions can be modulated for fine tuning of gene expression as desired.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: October 10, 2023
    Assignee: Trustees of Boston University
    Inventors: Ahmad S. Khalil, Caleb J. Bashor, Nikit Patel, James J. Collins
  • SYSTEMS AND METHODS FOR CONTROL OF GENE EXPRESSION
    Publication number: 20230313215
    Abstract: Embodiments disclosed herein provide artificial expression systems comprising multivalent transcription factor complexes for cooperative transcription factor assembly and modulating gene expression. More specifically, engineered synthetic transcription factors are recruited and structurally organized on synthetic gene circuits using molecular clamps, where the strength of intra-complex interactions can be modulated for fine tuning of gene expression as desired.
    Type: Application
    Filed: May 31, 2023
    Publication date: October 5, 2023
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Ahmad S. Khalil, Caleb J. Bashor, Nikit Patel, James J. Collins
  • SYSTEMS AND METHODS FOR CONTROL OF GENE EXPRESSION
    Publication number: 20200002710
    Abstract: Embodiments disclosed herein provide artificial expression systems comprising multivalent transcription factor complexes for cooperative transcription factor assembly and modulating gene expression. More specifically, engineered synthetic transcription factors are recruited and structurally organized on synthetic gene circuits using molecular clamps, where the strength of intra-complex interactions can be modulated for fine tuning of gene expression as desired.
    Type: Application
    Filed: June 28, 2019
    Publication date: January 2, 2020
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Ahmad S. Khalil, Caleb J. Bashor, Nikit Patel, James J. Collins