Abstract: A flushing apparatus for use with an IV infusion set and an IV infusion set having an automatic flushing function. The IV set includes a rigid and/or non-collapsible flushing liquid chamber (3), that is connected directly by a flushing port (7) to a fluid flow path for the IV fluid at a flushing height (FH) and by a venting port (17) at a venting height (VH). When the level of IV liquid in the fluid flow path falls below the venting height (VH) the venting port (17) allows air from the fluid flow path to enter the flushing liquid chamber (2) and flushing liquid from the flushing liquid chamber (2) to enter the fluid flow path via the flushing port (7) when, during use of the IV infusion set the IV liquid level falls below the venting height (VH), thereby allowing the flushing liquid chamber (2) to be drained by gravity into the fluid flow path.

Abstract: The present invention relates to a composition for reducing sweating in humans, characterized in that said composition comprises a compound capable of reduction of ITPR2 protein function and reduction of levels of ITPR2 mRNA and/or ITPR2 protein, and optionally pharmaceutically acceptable carriers and/or excipients, as well as to methods of treatment and specific siRNA molecules and their use in therapy.

Abstract: The present invention relates to a composition for reducing sweating in humans, characterized in that said composition comprises a compound capable of reduction of ITPR2 protein function and reduction of levels of ITPR2 mRNA and/or ITPR2 protein, and optionally pharmaceutically acceptable carriers and/or excipients, as well as to methods of treatment and specific siRNA molecules and their use in therapy.

Abstract: The present invention relates to a composition for reducing sweating in humans, characterized in that said composition comprises a compound capable of reduction of ITPR2 protein function and reduction of levels of ITPR2 mRNA and/or ITPR2 protein, and optionally pharmaceutically acceptable carriers and/or excipients, as well as to methods of treatment and specific siRNA molecules and their use in therapy.

Abstract: The present invention relates to a composition for reducing sweating in humans, characterized in that said composition comprises a compound capable of reduction of ITPR2 protein function and reduction of levels of ITPR2 mRNA and/or ITPR2 protein, and optionally pharmaceutically acceptable carriers and/or excipients, as well as to methods of treatment and specific siRNA molecules and their use in therapy.

Abstract: The present invention describes the chromosomal location of obesity susceptibility genes and provides methods for detecting the presence of such genes. The present invention enables the development of novel therapies to treat obesity.

Abstract: The present invention relates to a tyrosine-phosphatase-related protein, a DNA which codes for such a protein and a process for producing such a protein. In addition, the invention concerns the use of the DNA and protein and antibodies directed against the protein.