Patents by Inventor Niklas Schone

Niklas Schone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regioselective acylation of rapamycin at the C-42 position
    Patent number: 9051336
    Abstract: The invention refers to the selective acylation of Rapamycin at the 42-position (I) with an acylating agent of the formula (II) wherein R4 and R5 are the same or different, individually the rest of an acetal, especially tetrahydropyran, or of a carbonate or the rest of a silyl ether or taken together are the rest of a boronate, an acetal or ketal.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: June 9, 2015
    Assignee: SANDOZ
    Inventors: Wolfgang Felzmann, Niklas Schone
  • REGIOSELECTIVE ACYLATION OF RAPAMYCIN AT THE C-42 POSITION
    Publication number: 20140081016
    Abstract: The invention refers to the selective acylation of Rapamycin at the 42-position (I) with an acylating agent of the formula (II) wherein R4 and R5 are the same or different, individually the rest of an acetal, especially tetrahydropyran, or of a carbonate or the rest of a silyl ether or taken together are the rest of a boronate, an acetal or ketal.
    Type: Application
    Filed: March 30, 2012
    Publication date: March 20, 2014
    Applicant: SANDOZ AG
    Inventors: Wolfgang Felzmann, Niklas Schone