Patents by Inventor Niko Gubernator

Niko Gubernator has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • pH-responsive fluorescent false neurotransmitters and their use
    Patent number: 9075014
    Abstract: This invention relates to compounds having the following structure: wherein Y is O, X is O, bond ? is absent and bond ? is present, or Y is H, X is CH, bond ? is present, and bond ? is absent; atom Z is a carbon and bonds ?, ? and ? are present, or atom Z is a nitrogen and bonds ?, ? and ? are absent, or atom Z is a nitrogen and bonds ? and ? are present and ? is absent. R1, R2, R3, R4, R5, and R6 are various substituents as described in the specification.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: July 7, 2015
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Dalibor Sames, David Sulzer, Minhee Lee, Niko Gubernator
  • PH-RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE
    Publication number: 20130171664
    Abstract: This invention relates to compounds having the following structure: wherein Y is O, X is O, bond ? is absent and bond ? is present, or Y is H, X is CH, bond ? is present, and bond ? is absent; atom Z is a carbon and bonds ?, ? and ? are present, or atom Z is a nitrogen and bonds ?, ? and ? are absent, or atom Z is a nitrogen and bonds ? and ? are present and ? is absent. R1, R2, R3, R4, R5, and R6 are various substituents as described in the specification.
    Type: Application
    Filed: January 28, 2011
    Publication date: July 4, 2013
    Inventors: Dalibor Sames, David Sulzer, Minhee Lee, Niko Gubernator
  • Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B)
    Publication number: 20080194522
    Abstract: The present invention relates to compounds useful for detecting the activity of monoamine oxidases, compounds useful for competitively inhibiting monoamine oxidases, for determining inhibitors of monoamine oxidases and compounds useful for treating monoamine oxidase-related nervous system pathologies, as well as pharmaceutical compositions and methods of manufacture thereof.
    Type: Application
    Filed: August 25, 2005
    Publication date: August 14, 2008
    Inventors: Gong Chen, Dominic J. Yee, Niko Gubernator