Patents by Inventor Niko Schmiedeberg

Niko Schmiedeberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,4 Substituted Pyrazolopyrimidines as Kinase Inhibitors
    Publication number: 20080096868
    Abstract: The invention relates to 1,4-substituted pyrazolopyrimidine compounds of the formula I, pharmaceuticals comprising a 1,4-substituted pyrazolopyrimidine compound, the use of a 1,4-substituted pyrazolopyrimidine compound in the treatment or the use thereof in the manufacture of a pharmaceutical formulation for the treatment of a disease that depends on inadequate activity of a protein kinase, methods of treatment comprising administering a 1,4-substituted pyrazolopyrimidine compound, methods for the manufacture of a novel compound of that class, and novel intermediates and partial steps for their synthesis.
    Type: Application
    Filed: November 10, 2005
    Publication date: April 24, 2008
    Inventors: Niko Schmiedeberg, Pascal Furet, Patricia Imbach, Philipp Holzer
  • Cyclic peptidomimetic urokinase receptor antagonists
    Patent number: 7314863
    Abstract: The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: January 1, 2008
    Assignee: Wilex AG
    Inventors: Olaf Wilhelm, Horst Kessler, Markus Buergle, Nils Potthoff, Niko Schmiedeberg
  • Cyclic peptidomimetic urokinase receptor antagonists
    Publication number: 20060105943
    Abstract: The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
    Type: Application
    Filed: December 30, 2005
    Publication date: May 18, 2006
    Applicant: Wilex AG
    Inventors: Olaf Wilhelm, Horst Kessler, Markus Buergle, Nils Potthoff, Niko Schmiedeberg
  • Cyclic peptidomimetic urokinase receptor antagonists
    Patent number: 7045504
    Abstract: The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: May 16, 2006
    Assignee: Wilex AG
    Inventors: Olaf Wilhelm, Horst Kessler, Markus Buergle, Nils Potthoff, Niko Schmiedeberg
  • Cyclic peptidomimetic urokinase receptor antagonists
    Patent number: 6906032
    Abstract: The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: June 14, 2005
    Assignee: Wilex AG
    Inventors: Olaf Wilhelm, Horst Kessler, Markus Bürgle, Nils Potthoff, Niko Schmiedeberg
  • Cyclic peptidomimetic urokinase receptor antagonists
    Publication number: 20050101526
    Abstract: The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
    Type: Application
    Filed: December 22, 2004
    Publication date: May 12, 2005
    Applicant: Wilex AG
    Inventors: Olaf Wilhelm, Horst Kessler, Markus Burgle, Nils Potthoff, Niko Schmiedeberg
  • Urokinase peptide structure mimetics
    Publication number: 20030232389
    Abstract: The NMR structure of the peptidic urokinase type plasminogen activator antagonist cyclo[21,29][D-Cys21Cys29]-uPA21-30 has been solved to identify design strategies for peptidomimetics that interfere with the binding of urokinase type plasminogen activator with its receptor.
    Type: Application
    Filed: February 21, 2003
    Publication date: December 18, 2003
    Inventors: Olaf G Wilhelm, Markus Brgle, Horst Kessler, Niko Schmiedeberg