Abstract: An injection guide globally aligns an injector to an angle selected for consistent subcutaneous delivery of an injectate, while locally aligning a patient's skin normal to the injection path at the location where the injection pierces the skin. This arrangement advantageously maintains controlled contact between an injector and a subject's skin in order to deliver the full, intended volume of injectate into the patient's subcutaneous layer while avoiding misdelivery into adjacent layers such as the patient's dermis or muscle.

Abstract: An injection guide globally aligns an injector to an angle selected for consistent subcutaneous delivery of an injectate, while locally aligning a patient's skin normal to the injection path at the location where the injection pierces the skin. This arrangement advantageously maintains controlled contact between an injector and a subject's skin in order to deliver the full, intended volume of injectate into the patient's subcutaneous layer while avoiding misdelivery into adjacent layers such as the patient's dermis or muscle.

Abstract: An injection guide globally aligns an injector to an angle selected for consistent subcutaneous delivery of an injectate, while locally aligning a patient's skin normal to the injection path at the location where the injection pierces the skin. This arrangement advantageously maintains controlled contact between an injector and a subject's skin in order to deliver the full, intended volume of injectate into the patient's subcutaneous layer while avoiding misdelivery into adjacent layers such as the patient's dermis or muscle.

Abstract: An exemplary embodiment of the invention is a nozzle, for use in an injection device, that projects material at an ultra-high velocity. The nozzle includes an integrally formed body having an interior passageway that has a longitudinal axis. The input of the nozzle is configured to interface with a cartridge, and the output is configured to be placed proximate to a target. The passageway includes a taper, and its path length, from an initial diameter to a position along the passageway where the passageway first reaches a smallest diameter, is at least 0.5 mm. The taper of the passageway defines a shape, in a plane that includes the longitudinal axis, that is a continuous and monotonically decreasing function of distance along the longitudinal axis in a direction of flow through the nozzle.

Abstract: An exemplary embodiment of the invention is a nozzle, for use in an injection device, that projects material at an ultra-high velocity. The nozzle includes an integrally formed body having an interior passageway that has a longitudinal axis. The input of the nozzle is configured to interface with a cartridge, and the output is configured to be placed proximate to a target. The passageway includes a taper, and its path length, from an initial diameter to a position along the passageway where the passageway first reaches a smallest diameter, is at least 0.5 mm. The taper of the passageway defines a shape, in a plane that includes the longitudinal axis, that is a continuous and monotonically decreasing function of distance along the longitudinal axis in a direction of flow through the nozzle.

Abstract: An exemplary embodiment of the invention is a nozzle, for use in an injection device, that projects material at an ultra-high velocity. The nozzle includes an integrally formed body having an interior passageway that has a longitudinal axis. The input of the nozzle is configured to interface with a cartridge, and the output is configured to be placed proximate to a target. The passageway includes a taper, and its path length, from an initial diameter to a position along the passageway where the passageway first reaches a smallest diameter, is at least 0.5 mm. The taper of the passageway defines a shape, in a plane that includes the longitudinal axis, that is a continuous and monotonically decreasing function of distance along the longitudinal axis in a direction of flow through the nozzle.

Abstract: An injection guide globally aligns an injector to an angle selected for consistent subcutaneous delivery of an injectate, while locally aligning a patient's skin normal to the injection path at the location where the injection pierces the skin. This arrangement advantageously maintains controlled contact between an injector and a subject's skin in order to deliver the full, intended volume of injectate into the patient's subcutaneous layer while avoiding misdelivery into adjacent layers such as the patient's dermis or muscle.

Abstract: An exemplary embodiment of the invention is a nozzle, for use in an injection device, that projects material at an ultra-high velocity. The nozzle includes an integrally formed body having an interior passageway that has a longitudinal axis. The input of the nozzle is configured to interface with a cartridge, and the output is configured to be placed proximate to a target. The passageway includes a taper, and its path length, from an initial diameter to a position along the passageway where the passageway first reaches a smallest diameter, is at least 0.5 mm. The taper of the passageway defines a shape, in a plane that includes the longitudinal axis, that is a continuous and monotonically decreasing function of distance along the longitudinal axis in a direction of flow through the nozzle.