Patents by Inventor Nikolai B. Leonidov

Nikolai B. Leonidov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing physically stable crystalline gamma modification of para-aminobenzenesulfonamide
    Patent number: 5602281
    Abstract: A process for preparing a physically stable crystalline .gamma.-modification of para-aminobenzenesulfonamide comprises cooling a para-aminobenzenesulfonamide solution in water or an organic solvent at rate of at least 2.degree. C./min to complete crystallization thereof and subsequently separating the resulting crystals and drying thereof.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: February 11, 1997
    Inventor: Nikolai B. Leonidov
  • Crystalline modification of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine, a method for the preparation thereof and a medicinal preparation based on it
    Patent number: 5543147
    Abstract: A crystalline modification of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine prepared by cooling a solution of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine in water, an organic solvent or in a mixture thereof with a cooling agent at a rate not below 6.degree. C./min to crystallization followed by separation of the obtained crystals and drying them. The crystalline modification has high antiinflammatory and wound-healing activity and is an active substance in medicaments used for treatment of burns and wounds of various organs.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: August 6, 1996
    Assignee: Nikolai B. Leonidov
    Inventors: Nikolai B. Leonidov, Nikolai G. Selezenev
  • Antimicrobial interferon-inducing medicament
    Patent number: 5510387
    Abstract: An antimicrobial and interferon-inducing composition containing the crystalline gamma-modification of para-amino benzenesulfanilamide and a method for inducing interferon by administering a composition containing crystalline gamma-modification of para-amino benzenesulfanilamide.
    Type: Grant
    Filed: July 13, 1994
    Date of Patent: April 23, 1996
    Assignee: Nikolai Borisovich Leonidov
    Inventors: Nikolai B. Leonidov, Nikolai G. Seleznev
  • Crystalline modification of 2-dimethylaminoethyl-n-butylaminobenzoate hydrochloride, method for production thereof and pharmaceutical preparation for anaesthesia of eyes, based thereon
    Patent number: 5453532
    Abstract: A novel crystalline modification of 2-dimethylaminoethyl-n-butylaminobenzoate hydrochloride is characterized by a melting point of 148.6.degree..+-.0.3.degree. C. and has an interplanar spacing d and relative intensities defined herein, and a method for making said crystal. The compound of the invention is has local anaesthetic activity and is an active principle of a pharmaceutical preparation for the eyes.
    Type: Grant
    Filed: July 26, 1994
    Date of Patent: September 26, 1995
    Inventor: Nikolai B. Leonidov
  • Crystalline modification of 2-dimethylaminoethyl-n-butylaminobenzoate hydrochloride, method for production thereof and pharmaceutical preparation for anaesthesia of eyes, based thereon
    Patent number: 5403951
    Abstract: A novel crystalline modification of 2-dimethylaminoethyl-n-butylaminobenzoate hydrochloride and a method for production of said compound residing in that a solution of 2-dimethylaminoethyl-n-butylaminobenzoate hydrochloride of polymorphic form in water or organic solvent, or in their mixture, is cooled by a cooling agent at a rate of no less than 8.degree. C./min till complete crystallization of the solution with subsequent drying of obtained crystals.Compound of the invention has a local anaesthetic activity and is an active principle of a pharmaceutical preparation for anaesthesia of eyes (content of active principle is from 0.05 to 0.5% by mass).
    Type: Grant
    Filed: December 22, 1992
    Date of Patent: April 4, 1995
    Inventor: Nikolai B. Leonidov