Patents by Inventor Nikolai Beek

Nikolai Beek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of human glycosylated proteins in transgenic insects
    Publication number: 20070067855
    Abstract: This invention relates, e.g., to transgenic insects, or progeny thereof, whose cells contain at least one genomically integrated, expressible, nucleic acid encoding two or more of a set of Nglycosylation enzymes that can glycosylate a heterologous protein with a mammalianized (e.g., humanized) glycosylation pattern. The glycosylation genes are preferably expressed in the insect cells in catalytic amounts. Also described are methods to use such a transgenic insect to produce heterologous, mammalianized polypeptides of interest.
    Type: Application
    Filed: October 28, 2004
    Publication date: March 22, 2007
    Applicant: Chesapeake Perl, Inc.
    Inventors: Donald Jarvis, Nikolai Beek, Malcolm Fraser