Patents by Inventor Nikolai Fedorov

Nikolai Fedorov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8901151
    Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: December 2, 2014
    Assignee: Targacept, Inc.
    Inventors: Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A. Munoz, Jason Speake, Daniel Yohannes
  • Publication number: 20140163065
    Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Application
    Filed: May 14, 2013
    Publication date: June 12, 2014
    Applicant: TARGACEPT, INC.
    Inventors: Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A. Munoz, Jason Speake, Daniel Yohannes
  • Publication number: 20140107163
    Abstract: The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Applicant: Targecept, Inc.
    Inventors: Srinvasa Rao Akireddy, Scott R. Breining, Timothy J. Cuthbertson, Gary Maurice Dull, Gregory J. Gatto, John Genus, Phillip S. Hammond, Joseph Pike Mitchener, JR., Julio A. Munoz, Pieter Albert Otten, Daniel Yohannes, Nikolai Fedorov
  • Patent number: 8633227
    Abstract: The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: January 21, 2014
    Assignee: Targacept, Inc.
    Inventors: Srinivasa Rao Akireddy, Scott R. Breining, Timothy J. Cuthbertson, Gary Maurice Dull, Gregory J. Gatto, John Genus, Philip S. Hammond, Joesph Pike Mitchener, Jr., Julio A. Munoz, Pieter Albert Otten, Daniel Yohannes, Nikolai Fedorov
  • Patent number: 8541446
    Abstract: The present invention relates to (2S,3R)—N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms thereof, methods for its preparation, novel intermediates, and methods for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central and autonomic nervous systems.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: September 24, 2013
    Assignee: Targacept, Inc.
    Inventors: Merouane Bencherif, Lisa Benson, Gary Maurice Dull, Nikolai Fedorov, Gregory J. Gatto, Kristen G. Jordan, Anatoly A. Mazurov, Lan Miao, Julio A. Munoz, Inigo Pfeiffer, Sondra Pfeiffer, Teresa Phillips
  • Patent number: 8476296
    Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: July 2, 2013
    Assignee: Targacept, Inc.
    Inventors: Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A. Munoz, Jason Speake, Daniel Yohannes
  • Publication number: 20120015983
    Abstract: The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.
    Type: Application
    Filed: November 30, 2009
    Publication date: January 19, 2012
    Applicant: Targacept, Inc.
    Inventors: Srinivasa Rao Akireddy, Scott R. Breining, Timothy J. Cuthbertson, Gary Maurice Dull, Gregory J. Gatto, John Genus, Philip S. Hammond, Joseph Pike Mitchener, Julio A. Munoz, Pieter Albert Otten, Daniel Yohannes, Nikolai Fedorov
  • Publication number: 20110257224
    Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetyl-choline receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Application
    Filed: January 25, 2010
    Publication date: October 20, 2011
    Applicant: Targacept, Inc
    Inventors: Merouane Bencherif, Nikolai Fedorov, Terry Hauser, Kristen Jordan, Sharon Rae Letchworth, Anatoly Mazurov, Julio A. Munoz, Jason Speake, Daniel Yohannes
  • Publication number: 20110257168
    Abstract: The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Application
    Filed: July 1, 2009
    Publication date: October 20, 2011
    Applicant: Targacept, Inc.
    Inventors: Srinivasa R. Akireddy, Scott R. Breining, Nikolai Fedorov, David Kombo, Anatoly A. Mazurov, Lan Miao, Srinivasa V. Murthy, Todd Showalter, Yunde Xiao, Daniel Yohannes
  • Publication number: 20090048290
    Abstract: The present invention relates to (2S,3R)—N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms thereof, methods for its preparation, novel intermediates, and methods for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central and autonomic nervous systems.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 19, 2009
    Inventors: Merouane Bencherif, Lisa Benson, Gary Maurice Dull, Nikolai Fedorov, Gregory J. Gatto, John Genus, Kristen G. Jordan, Jacob Mathew, Anatoly A. Mazurov, Lan Miao, Julio A. Munoz, Inigo Pfeiffer, Sondra Pfeiffer, Teresa Y. Phillips
  • Publication number: 20050131463
    Abstract: The invention includes several embodiments of a device for recording electrical activity, particularly the electrical field, from nerve, particularly brain, tissue slices. The device is preferably used for the testing or screening of the effect of physiologically active compounds on the electrical activity of brain tissue slices, which is either electrically evoked or spontaneously occurring. Thus, the invention also includes methods for testing or screening using the device in this manner, for example, to identify compounds that can enhance long term potentiation.
    Type: Application
    Filed: December 12, 2003
    Publication date: June 16, 2005
    Inventors: Nikolai Fedorov, Timothy Michael, Galina Oksman, Ana Chow, Gregory Rose
  • Patent number: 4440224
    Abstract: For mining combustible minerals a plurality of boreholes are drilled in a gasifiable seam, e.g., in a coal bed, said boreholes 1 through 4 being intercommunicated by a number of gasification ducts. Then the combustible mineral is initiated to fire, and an oxygen-containing blast gas is blown through some of said boreholes into the gasification ducts, with the result that the generator gas is formed. Simultaneously a carbon- and/or hydrogen-containing blast gas is blown through other boreholes situated along the flow of the generator gas to enrich the latter with combustible ingredients. As a result some chemical reactions proceed under the effect of heat produced by the generator gas, whereby additional amounts of combustible elements are formed which add to the calorific value of the generator gas being withdrawn. The method is instrumental also in controlling the composition of the generator gas withdrawn by varying the ratio of the components of the blast gas enriching the generator gas.
    Type: Grant
    Filed: June 21, 1979
    Date of Patent: April 3, 1984
    Assignee: Vesojuzny Nauchno-Issledovatelsky Institut Ispolzovania Gaza V Narodnom Khozyaistve I Podzemnogo Khranenia Nefti, Nefteproduktov I Szhizhennykh Gazov (Vniipromgaz)
    Inventors: Efim V. Kreinin, Kirill N. Zvyagimtsev, Nikolai A. Fedorov
  • Patent number: 4211632
    Abstract: According to the invention pulverized brown coal is processed by heating brown coal in two stages. During the first stage brown coal being processed is heated by a gaseous heat carrier to a temperature at which thermal decomposition of the brown coal begins. During the second stage the brown coal being processed is heated by the gaseous heat carrier to a temperature at which an intensive thermal decomposition of the brown coal takes place. The stream of the gaseous heat carrier delivered at the second stage of heating is fed with air oxygen and with low-grade products, such as heavy tars and pyrogenic water which are sprayed into the gaseous heat carrier.
    Type: Grant
    Filed: August 14, 1978
    Date of Patent: July 8, 1980
    Assignee: Gosudarstvenny Nauchno-Issledovatelsky Energetichesky Institut Imeni G.M. Krzhizhanovskogo
    Inventors: Zinovy F. Chukhanov, Anatoly M. Nikolaev, Vadim A. Karasev, Elizaveta A. Shapatina, Zinovy Z. Chukhanov, Galina P. Zybalova, Nikolai A. Fedorov, Sergei A. Tsuprov