Patents by Inventor Nikolai K. Yankovsky

Nikolai K. Yankovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial strain of escherichia coli BKIIM B-3996 as the producer of l-threonine
    Patent number: 5538873
    Abstract: A bacterial strain of Escherichia coli BKIIM B-3996, a producer of L-threonine, containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antibiotics Research Institute under Reg. No. 1867.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: July 23, 1996
    Assignee: Ajinomoto Co., Inc.
    Inventors: Vladimir G. Debabov, Jury I. Kozlov, Evgeny M. Khurges, Vitaly A. Livshits, Nelli I. Zhdanova, Mikhail M. Gusyatiner, Alexandr K. Sokolov, Tatyana A. Bachina, Nikolai K. Yankovsky, Jury D. Tsygankov, Andrei J. Chistoserdov, Tatyana G. Plotnikova, Irina C. Shakalis, Alla V. Belareva, Raisa A. Arsatiants, Albert F. Sholin, Tamara M. Pozdnyakova
  • Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine
    Patent number: 5175107
    Abstract: A bacterial strain of Escherichia coli BKIIM B-3996, a producere of L-threonine, containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antibiotics Research Institute under Reg. No. 1867.
    Type: Grant
    Filed: June 12, 1990
    Date of Patent: December 29, 1992
    Assignee: Ajinomoto Co., Inc.
    Inventors: Vladimir G. Debabov, Jury I. Kozlov, Evgeny M. Khurges, Vitaly A. Livshits, Nelli I. Zhdanova, Mikhail M. Gusyatiner, Alexandr K. Sokolov, Tatyana A. Bachina, Nikolai K. Yankovsky, Jury D. Tsygankov, Andrei J. Chistoserdov, Tatyana G. Plotnikova, Irina O. Shakalis, Alla V. Belareva, Raisa A. Arsatiants, Albert F. Sholin, Tamara M. Pozdnyakova
  • Process for producing L-threonine
    Patent number: 4321325
    Abstract: The process for producing L-threonine consists in that there is cultivated a producer of L-threonine in the capacity of which is used the Escherichia coli strain VNIIgenetika M-1 deposited in the Central museum of commercial microorganisms under the All-Union Research Institute for Genetics and Selection of Commercial Microorganisms at a registration No. IIMIIB-1856. The above strain has been selected on the basis of natural variability of the Escherichia coli strain VNIIgenetika VL 334/p YN7), obtained by virtue of the genetic engineering techniques through increasing the dose of mutant genes capable of a higher rate of L-threonine production, by introducing a multicopy hydrid plasmid carrying said genes, into a mutant recipient strain. The abovesaid producer is cultivated on a nutrient medium, containing sources of carbon, nitrogen, and some mineral salts in the presence of an antibiotic penicillin, the resultant biomass being then separated from the culture fluid, whereupon the end product is isolated.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: March 23, 1982
    Inventors: Vladimir G. Debabov, Nelli I. Zhdanova, Alexandr K. Sokolov, Vitaly A. Livshits, Jury I. Kozlov, Evgeny M. Khurges, Nikolai K. Yankovsky, Mikhail M. Gusyatiner, Albert F. Sholin, Viktor P. Antipov, Tamara M. Pozdnyakova
  • Method for preparing strains which produce aminoacids
    Patent number: 4278765
    Abstract: A method for constructing strains which produce aminoacids comprising combining of a DNA chromosome fragment of a donor microorganism containing genes controlling the synthesis of a selected aminoacid and having a mutation destroying the negative regulation of the synthesis of this aminoacid with a vector DNA molecule to form a hybrid DNA molecule. Use is made of a vector DNA molecule capable of providing amplification of the hybrid DNA molecule. The resulting hybrid DNA molecule is used for transforming cells of the recipient strain having the mutation blocking the synthesis of the selected aminoacid in this strain and the mutation partly blocking the related step of metabolism of this aminoacid to yield the strain capable of increased productivity of the selected aminoacid.
    Type: Grant
    Filed: June 28, 1979
    Date of Patent: July 14, 1981
    Inventors: Vladimir G. Debabov, Jury I. Kozlov, Nelli I. Zhdanova, Evgeny M. Khurges, Nikolai K. Yankovsky, Mikhail N. Rozinov, Rustem S. Shakulov, Boris A. Rebentish, Vitaly A. Livshits, Mikhail M. Gusyatiner, Sergei V. Mashko, Vera N. Moshentseva, Ljudmila F. Kozyreva, Raisa A. Arsatiants