Patents by Inventor Nikolai N. Vsevolodov

Nikolai N. Vsevolodov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8597932
    Abstract: The invention involves developing and stabilizing cultivating droplets within a matrix of a porous medium. A cultivation medium may be selected, prepared and mixed with a surfactant. Where cells are desired to be cultured in droplets, cells may be added. The mixture may be converted into cultivating droplets. The cultivating droplets may be stabilized by introducing them to a porous medium. The porous medium may contain hydrophobic particles. Stabilized, cultivating droplets having one or more cells may form an aseptic microenvironment for the concentrated growth of cells.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: December 3, 2013
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov
  • Publication number: 20110105344
    Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 5, 2011
    Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
  • Patent number: 7850915
    Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: December 14, 2010
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
  • Publication number: 20100275780
    Abstract: The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.
    Type: Application
    Filed: July 8, 2010
    Publication date: November 4, 2010
    Inventors: Charles L. Bailey, Victor Morozov, Nikolai N. Vsevolodov
  • Patent number: 7776405
    Abstract: The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: August 17, 2010
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Charles L. Bailey, Victor Morozov, Nikolai N. Vsevolodov
  • Publication number: 20080152233
    Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.
    Type: Application
    Filed: March 3, 2008
    Publication date: June 26, 2008
    Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
  • Patent number: 7368288
    Abstract: The invention contemplates a method for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization pattern”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. It has been shown that changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. It was also found that both the character of changer in the crystallization patter and the fact of such changes can be used as recognition elements in analysis of protein molecules.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: May 6, 2008
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott