Abstract: The main characteristic of method is that before the onset of menopause in women at age 30-45 years, part of the cortical and medulla layers of one or both ovaries is surgically resected and cryopreserved (frozen), and in perimenopause beginning, these tissues are autotransplanted subcutaneously in a form of suspension or small ovarian pieces prepared from thawed tissues fragments of their own ovaries. This “return” is repeatedly periodically each 4-6 months for 10-15 years. That helps to obtain normal level of ovarian antiage factors in blood till age 60-65 years, thus slowing aging.