Abstract: A method for treating the side effects resulting from ophthalmic lasery surgery of the eye. The method administers stem cells as a means for treating the destruction of retinal and other tissues resulting from photocoagulation in the treatment of diabetic retinopathy and other eye disorders. Methods for using the invention with other ophthalmic laser surgical procedures, and other eye disorders, are also disclosed.

Abstract: Angiogenically induced transplants and methods for their use and manufacture are disclosed. The angiogenic potential of the transplants is increased by contacting the transplants with donor mesenchymal cells such as hair follicle dermal papilla stem cells. Methods for treating disorders and diseases, such as disorders of the skin and angiopathies, are also disclosed.

Abstract: A spongiform scaffold which comprises epithelial stem cells, and free of mesenchymal cells. A spongiform scaffold comprising precursor keratinocytes for use in a method of transplantion of the scaffold to an epithelial cell target site in a recipient, resulting in growth of said epithelial stem cells and the ingrowth of cells from the body of said recipient to restore tissue. A version of the scaffold is formed from collagen, and in particular, Spongostan™.

Abstract: A process utilizing an electromagnetic and mechanical energy to produce tissue damage in small regions of skin without damage to neighboring tissue. This permits healthy physiological responses originating in the neighboring tissue to repair the damaged tissue or to produce new healthy tissue to replace the damaged tissue including stem cells attraction. Topical application of stem cells extracts and growth factors to mobilize into the damaged area local and systemic stem cells. And a wide variety of energy sources may be utilized.

Abstract: Method of treating retinal disease by intravitreally injecting defined cytokine-transfected stem cell population; adipose-derived stem cell comprising transient wound-healing trangenes; defined homogeneous and heterogeneous populations of cytokine-transfected adipose-derived stem cells; method of treating retinal disease involves step of laser-inducing retinal injury followed by intravitreally injecting a population of stem cells comprising transiently transfected stem cells into the eye of the mammal in a number sufficient for repopulation, intraretinal integration and differentiation into normal photoreceptor cells.

Abstract: A spray of cryogen is patterned to create a pattern of cooled regions on a target tissue for cosmetic dermatological treatment. In one embodiment, the cryogen is patterned using a heated mask. An optical source is configured to irradiate the target tissue in a region at least partially overlapping the cooled regions to create a pattern of treatment zones. A control unit adjusts the timing of between the cryogen and optical pulses.

Abstract: A process utilizing a separating shield to produce tissue damage in small regions of skin without damage to neighboring tissue. This permits healthy physiological responses originating in the neighboring tissue to repair the damaged tissue or to produce new healthy tissue to replace the damaged tissue. In preferred embodiments a variety of separating shield materials are used to protect the neighboring tissues. And a wide variety of radiation sources may be utilized.

Abstract: Micro-clustered liquids, methods of manufacture and use. Culture media and cultures comprising micro-clustered water; use of micro-clustered culture media and cultures for cell, tissue and organ maintenance and growth; use in microbial biotechnology.

Abstract: Micro-clustered water compositions of bio-affecting agents, body-treating agents, and adjuvants or carriers, pharmaceutical and diagnostic compositions thereof. Methods of using the compositions involving administering them ex vivo to cells, tissues or organs, or in vivo to living bodies; and methods of making the compositions.

Abstract: A skin treatment laser device suitable for home use. The device includes an array of at least two types of laser units. A first type of laser units operates at a wavelength chosen to heat the skin generally and a second type of laser units operates at a wavelength chosen to produce tissue damage in extremely small and separated regions of the skin. No skin damage occurs in tissue surrounding the regions of skin transformation or destruction. Natural healing processes originating in the surrounding tissue heal the damaged tissue and produce general rejuvenation effects in the skin tissue. Laser beams from at least the second type of laser units are focused into the small regions to be damaged. A preferred focusing technique utilizes cold sapphire cylindrical rods. Preferably, the skin to be treated is shaved or abraded prior to or simultaneously with the laser treatment to remove portion of the stratum corneum so to improve laser beam penetration.

Abstract: The invention describes a method and apparatus for the modulation of an immune response for the removal of a foreign body in skin or a visceral organ. A fractional phototherapy device is used to produce an acute stimulus for the immune response. The immune response may be enhanced by applying an exogenous substance. The immune modulation may be targeted or directed toward the treatment of a particular foreign body through the creation and amplification of particular biological signatures. This invention is particularly appropriate for treatment of skin cancer, autoimmune diseases, inflammatory diseases, and fungi.

Abstract: A process for delivering hair removal fluids to hair ducts. In a preferred embodiment the fluid is a vaccine for slowing or stopping hair growth and a process for applying the vaccine or other hair growth vaccines to the skin region having unwanted hair and a method of delivering the vaccine to skin regions of unwanted hair. The preferred vaccine consists of an antigen cocktail of weakened or essentially dead elements of hair follicles for stimulating antibody responses. The preferred vaccine is prepared from patient's own hair papilla or bulge area stem cells. In other embodiments vaccines are made from extracts of papilla cells cultivated in a laboratory. The vaccines produce antibodies and these antibodies attack and destroy hair papilla and block bulge area cells that would otherwise produce or stimulate a growth of new papilla cells. Even if any new papilla cells appear, the circulating antibodies of the vaccine-activated immune system attack and destroy them also.

Abstract: A method for utilizing an individual's undifferentiated papilla and/or bulge area stem cells to stimulate hair growth. The inventor has discovered that bulge area stem cells can be harvested, isolated, cloned, and successfully transplanted into an area of the donor's skin where increased growth of hair is desired to increase hair growth therein. In the first step of the method, a donor section of skin is identified having growth of the type of hair for which increased growth at the recipient site is sought. Since hair types differ according to their anatomical site, it is generally desirable to match the hair produced by the donor stem cells to the type of hair that is desired at the recipient site. For example, in treatment of male pattern baldness, tissue samples are harvested from an area of the scalp that still exhibits vigorous growth. Once the donor site is identified, it is anesthetized locally using any convenient means and a plurality of tissue samples are obtained from the donor site.

Abstract: An all-fiber erbium laser oscillating in a passive Q switched mode. The laser includes a crystal saturable absorber that may be Co2+:ZnSe or Cr2+:ZnSe. In preferred embodiments continuous pumping or short pulse pumping may be utilized. The laser is characterized by low threshold high-power, short-pulse generation. In preferred embodiments the threshold is only about 20 mW. The crystals are bleached at extremely low intensity, of about 0.8 kW/cm2 and provide moderate relaxation time of the excited state (290 ?s) within a spectral range of about 1400-1800 nm. The simplicity of the design and low cost of that laser 2000).

Abstract: A collector (202) captures light from source images as a field of pixels, a color analyzer (292) analyzes a proper subset (420) of the field to produce a plurality of color values, and a cosmetic analyzer then uses the color values to produce a cosmetic color determination. Another aspect of the present invention comprises a window having a light passage area, a color calibration region that is not coextensive with the light passage area, and a detectable product identification region. The window may also contain a mechanism that tends to preclude multiple uses. A third aspect of the present invention is a system that combines the collector, the color analyzer, the cosmetic analyzer, and window.

Abstract: Methods of hydrating foods and food ingredients in food processing systems with structured water. Edible foods, ingredients, flavoring and sweetening compositions containing structured water.

Abstract: Micro-clustered liquids, methods of manufacture and use. Culture media and cultures comprising micro-clustered water; use of micro-clustered culture media and cultures for cell, tissue and organ maintenance and growth; use in microbial biotechnology.

Abstract: Micro-clustered water compositions of bio-affecting agents, body-treating agents, and adjuvants or carriers, pharmaceutical and diagnostic compositions thereof. Methods of using the compositions involving administering them ex vivo to cells, tissues or organs, or in vivo to living bodies; and methods of making the compositions.

Abstract: Micro-clustered liquids, methods of manufacture and use. Culture media and cultures comprising micro-clustered water; use of micro-clustered culture media and cultures for cell, tissue and organ maintenance and growth; use in microbial biotechnology.

Abstract: A laser treatment device and process with controlled cooling. The device contains a cooling element with high heat conduction properties, which is transparent to the laser beam. A surface of the cooling element is held in contact with the tissue being treated while at least one other surface of the cooling element is cooled by the evaporation of a cryogenic fluid. The cooling is coordinated with the application of the laser beam so as to control the temperatures of all affected layers of tissues. In a preferred embodiment useful for removal of wrinkles and spider veins, the cooling element is a sapphire plate. A cryogenic spray cools the top surface of the plate and the bottom surface of the plate is in contact with the skin. In preferred embodiments the wavelength of the laser beam is chosen so that absorption in targeted tissue is low enough so that substantial absorption occurs throughout the targeted tissue. In a preferred embodiment for treating large spider veins with diameters in the range of 1.