Patents by Inventor Nikolas BUGDAHN

Nikolas BUGDAHN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108559
    Abstract: The present invention relates to a method for synthesizing sinapoyl malate comprising the steps of (a) (i) reacting syringaldehyde with acetic acid anhydride and an alkali metal acetate; or (ii) reacting sinapinic acid with acetic acid anhydride, and (b) cleaving the anhydride of the acetyl protected reaction product of (a) by exposing to water and an aliphatic alcohol to form protected sinapinic acid, (c) esterifyinig the protected sinapinic acid by reacting with an alkyl protected carboxylic acid ester to form protected sinapoyl malate, and (d) reacting the protected sinapoyl malate with aqueous acid to yield sinapoyl malate.
    Type: Application
    Filed: December 8, 2023
    Publication date: April 4, 2024
    Inventors: Nadine PERNODET, Chia-Wen CHEN, Kelly DONG, Jingyu HUANG, Oskar KOCH, Nikolas BUGDAHN
  • Patent number: 11911347
    Abstract: The present invention is in the field of antioxidants and relates to cosmetic or pharmaceutical, preferably dermatological, compositions or homecare product comprising or consisting of a synergistic combination of a specific antioxidant and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or homecare product, in particular for scavenging reactive oxygen species (ROS), for inhibition matrix metalloproteinases expression and/or for inhibiting interleukin 8 (IL-8) secretion.
    Type: Grant
    Filed: April 14, 2023
    Date of Patent: February 27, 2024
    Assignee: Symrise AG
    Inventors: Nikolas Bugdahn, Sven Siegel, Sabine Lange, Dominik Stuhlmann
  • Publication number: 20240050337
    Abstract: Suggested is mixture comprising or consisting of (a) at least one 1,2-alkanediol (b) at least one malodor causing compound existing as an impurity or degradation product within 1,2-alkanediols, and (c) at least one malodor reduction material having a Malodor Reduction Value (MORV) of at least 0.5 with improved odour properties.
    Type: Application
    Filed: December 9, 2020
    Publication date: February 15, 2024
    Inventors: Sven SIEGEL, Nikolas BUGDAHN, Sabine LANGE
  • Publication number: 20230364027
    Abstract: The present invention relates to a composition comprising or consisting of a synergistic combination of an effective amount of antimicrobial component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols. Furthermore, the present invention relates to food, cosmetic or pharmaceutical preparations comprising said composition. Additionally, the present invention refers to the use of said composition for suppressing or inhibiting microorganism growth in food, a cosmetic or a pharmaceutical preparation. Additionally, the present invention relates to the use of 1,2-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols in an effective amount for boosting the efficacy of an anitmicrobial active component. Finally, the present invention relates to a method for suppressing or inhbiting of microorganism growth in food, a cosmetic or a pharmaceutical preparation.
    Type: Application
    Filed: April 14, 2023
    Publication date: November 16, 2023
    Inventors: Sabine Lange, Nikolas Bugdahn, Christin Koch
  • Publication number: 20230338250
    Abstract: The present invention relates to a cosmetic or pharmaceutical, preferably dermatological, composition or homecare product comprising or consisting of a specific lipophilic active component and an effective amount of a 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and said compositions for personal care, or as a pharmaceutical or for animal care. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols for improving the solubility of a specific lipophilic active component in a cosmetic or pharmaceutical composition. Finally, the present invention relates to the use of 1,2-heptanediol and/ or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols as solubilizer replacer in a cosmetic or pharmaceutical composition or homecare product.
    Type: Application
    Filed: December 9, 2021
    Publication date: October 26, 2023
    Inventors: Sabine Lange, Nikolas Bugdahn, Ricarda Kraeling
  • Publication number: 20230338249
    Abstract: The present invention relates to compositions, including cosmetic, pharmaceutical or homecare compositions, comprising at least one linear 2,3-alkanediol having a carbon chain of 5 to 13 atoms. The compositions may further comprise at least one linear 1,2-alkanediol having a carbon chain of 5 to 13 carbon atoms. Additionally, the present invention relates to the use of the compositions of the present invention for enhancing the antioxidative effect of an antioxidant, for improving the sensory properties, i.e. skin sensation, of a liquid lipophilic component, for sebum control, or for malodour management, or for modulating fragrance notes, or for modification of fragrance notes, or for suppression of fragrance notes, or for topical applications, or for coverage of the malodour of 1-octen-3-ol, or for masking insect alluring odours, or for repelling insects.
    Type: Application
    Filed: December 9, 2021
    Publication date: October 26, 2023
    Inventors: Nikolas Bugdahn, Sabine Lange, Christin Koch, Frank Struever, Dietmar Droege
  • Publication number: 20230293403
    Abstract: The present invention relates to a cosmetic or pharmaceutical, preferably dermatological, composition comprising or consisting of a liquid lipophilic component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or for animal care. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or of a mixture of two or more different specific alkanediols for improving the sensor), properties, i.e. skin sensation, of a cosmetic or pharmaceutical composition upon topical application, or as silicone replacer.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Nikolas Bugdahn, Sebastian Bruncke, Vanessa Schade, Sabine Lange
  • Publication number: 20230293407
    Abstract: The present invention relates to a composition comprising or consisting of a synergistic combination of an effective amount of antimicrobial component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols. Furthermore, the present invention relates to food, cosmetic or pharmaceutical preparations comprising said composition. Additionally, the present invention refers to the use of said composition for suppressing or inhibiting microorganism growth in food, a cosmetic or a pharmaceutical preparation or homecare product. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols in an effective amount for boosting the efficacy of an antimicrobial active component.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Sabine Lange, Nikolas Bugdahn, Christin Koch
  • Publication number: 20230293404
    Abstract: The present invention relates to a cosmetic or pharmaceutical, preferably dermatological, composition or a homecare product comprising or consisting of a natural polymer and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and said compositions for personal care, as a pharmaceutical, for animal care or for homecare. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols in an effective amount for reducing antimicrobial load of a natural polymer and/or as an antimicrobial replacer. Finally, the present invention relates to a method for reducing antimicrobial load of a cosmetic or pharmaceutical composition or homecare product comprising a natural polymer.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Christin Koch, Sabine Lange, Ricarda Kraeling, Maik Mascher, Nikolas Bugdahn
  • Publication number: 20230293409
    Abstract: The present invention relates to a cosmetic or pharmaceutical, preferably dermatological, composition comprising or consisting of a specific antimicrobial component and an effective amount of 1,2-nonanediol and/or 2,3-nonanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or for animal care. Additionally, the present invention relates to the use of 1,2-nonanediol and/or 2,3-nonanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols for reducing or inhibiting antimicrobial activity on skin or scalp, and/or for balancing sebum production or reducing sebum overproduction on skin or scalp and/or for suppressing dandruff on skin, scalp or nails and/or as antimicrobial active component replacer.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Christin Koch, Sabine Lange, Nikolas Bugdahn
  • Publication number: 20230293406
    Abstract: The present invention relates to a homecare product composition or a cosmetic or pharmaceutical composition comprising or consisting of an effective amount of 1,2-nonanediol or 2,3-nonanediol or a mixture comprising 1,2-nonanediol and 2,3-nonanediol or of a specific alkanediol having a carbon chain of 5 to 14 carbon atoms or a mixture of two or more different specific alkanediols having a carbon chain of 5 to 14 carbon atoms, in combination with an effective amount of at least one cooling agent. Additionally, the present invention relates to the use of 1,2-nonanediol or 2,3-nonanediol or a mixture comprising 1,2-nonanediol and 2,3-nonanediol or the use of a specific alkanediol having a carbon chain of 5 to 14 carbon atoms or a mixture of two or more different specific alkanediols having a carbon chain of 5 to 14 carbon atoms for malodour reduction or for inhibiting malodour development or for body odour control or for masking insect alluring odours.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Christin Koch, Sabine Lange, Nikolas Bugdahn, Ricarda Kraeling, Steffen Nordzieke
  • Publication number: 20230293410
    Abstract: The present invention relates to a cosmetic or pharmaceutical, preferably dermatological, composition comprising or consisting of a liquid lipophilic component and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or for animal care. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or of a mixture of two or more different specific alkanediols for improving the sensory properties, i.e. skin sensation, of a cosmetic or pharmaceutical composition upon topical application, or as silicone replacer.
    Type: Application
    Filed: April 14, 2023
    Publication date: September 21, 2023
    Inventors: Nikolas Bugdahn, Sebastian Bruncke, Vanessa Schade, Sabine Lange
  • Publication number: 20230293408
    Abstract: The present invention is in the field of antioxidants and relates to cosmetic or pharmaceutical, preferably dermatological, compositions or homecare product comprising or consisting of a synergistic combination of a specific antioxidant and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or homecare product, in particular for scavenging reactive oxygen species (ROS), for inhibition matrix metalloproteinases expression and/or for inhibiting interleukin 8 (IL-8) secretion.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Nikolas Bugdahn, Sven Siegel, Sabine Lange, Dominik Stuhlmann
  • Publication number: 20230293405
    Abstract: The present invention refers in general to the area of sun care products and relates in particular to a cosmetic or pharmaceutical, in particular dermatological, composition or a homecare product comprising or consisting of a solid UV filter and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical, for animal care or as a homecare product. Additionally, the present invention relates to the use of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols for improving the solubility of a solid UV filter, and/or for improving the availability of a solid UV filter in a cosmetic or pharmaceutical composition or homecare product.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Sabine Lange, Nikolas Bugdahn, Vanessa Schade
  • Publication number: 20230295066
    Abstract: The present invention relates to a process for the efficient, sustainable and gentle preparation of bio-based alkanediols, especially 1,2-alkanediols, at moderate temperatures based on a recycling of side products and non-reacted educts. The present invention also relates to a composition comprising at least two alkanediols obtainable by said process and to the use of said composition in consumer product formulations. In addition, the present invention relates to consumer products as such comprising the inventive composition.
    Type: Application
    Filed: December 9, 2021
    Publication date: September 21, 2023
    Inventors: Nikolas Bugdahn, Frank Struever, Heiko Heinemeyer, Moritz Hoppe, Juergen Siewert, Sabine Lange, Bernhard Russbueldt
  • Publication number: 20230248626
    Abstract: The present invention relates to a cosmetic or pharmaceutical composition comprising an effective amount of at least one linear 1,2-alkanediol having a carbon chain of 5 to 13 carbon atoms and an effective amount of at least one linear 2,3-alkanediol having a carbon chain of 5 to 13 carbon atoms. Moreover, the present invention relates to a composition comprising an effective amount of at least one linear 1,2-alkanediol having a carbon chain of 5 to 13 carbon atoms and an effective amount of at least one linear 2,3-alkanediol having a carbon chain of 5 to 13 carbon atoms. Additionally, the present invention relates to the use of the compositions of the present invention for enhancing the antioxidative effect of an antioxidant, for improving the sensory properties, i.e.
    Type: Application
    Filed: April 14, 2023
    Publication date: August 10, 2023
    Inventors: Nikolas Bugdahn, Sabine Lange, Christin Koch, Frank Struever, Dietmar Droege
  • Publication number: 20230248663
    Abstract: The present invention is in the field of antioxidants and relates to cosmetic or pharmaceutical, preferably dermatological, compositions or homecare product comprising or consisting of a synergistic combination of a specific antioxidant and an effective amount of 1,2-heptanediol and/or 2,3-heptanediol or of a specific alkanediol or a mixture of two or more different specific alkanediols and the use of said compositions as a cosmetic, for personal care, as a pharmaceutical or homecare product, in particular for scavenging reactive oxygen species (ROS), for inhibition matrix metalloproteinases expression and/or for inhibiting interleukin 8 (IL-8) secretion.
    Type: Application
    Filed: April 14, 2023
    Publication date: August 10, 2023
    Inventors: Nikolas Bugdahn, Sven Siegel, Sabine Lange, Dominik Stuhlmann
  • Publication number: 20230167041
    Abstract: The invention relates to a method for producing limonene comprising or consisting of the following steps: (a) providing beta-pinene or a beta-pinene containing starting material; (b) admixing the starting material with a catalytically effective amount of a MWW-type zeolite; (C) heating the reaction mixture to a temperature in the range of between 60 and 100° C.; and optionally (d) separating the limonene or a limonene-enriched fraction from the sump.
    Type: Application
    Filed: February 18, 2020
    Publication date: June 1, 2023
    Inventors: Nikolas BUGDAHN, Diego JAIME, Bernhard RUßBÜLDT, Frank STRÜVER
  • Publication number: 20230144944
    Abstract: What is proposed is a continuous process for producing limonene which has the feature that beta-pinene or beta-pinene-containing starting materials are isomerized in a trickle-bed reactor in the presence of acid catalysts.
    Type: Application
    Filed: February 18, 2020
    Publication date: May 11, 2023
    Inventors: Nikolas BUGDAHN, Angela Köckritz, Elka KRALEVA, Reinhard ECKELT
  • Publication number: 20230118467
    Abstract: The present invention relates generally to: the cosmetic or pharmaceutical use of avenanthramide L or an oat extract comprising avenanthramide L; avenanthramide L or an oat extract comprising avenanthramide L as a neurokinin-1 receptor NK1R antagonist; and a method for preparing of preparing avenalumic acid and/or avenanthramide L.
    Type: Application
    Filed: March 6, 2020
    Publication date: April 20, 2023
    Inventors: Martina Herrmann, Gerhard Schmaus, Nikolas Bugdahn, Dominik Stuhlmann, Katharina Striewe, Holger Joppe