Patents by Inventor Nikolaus Gravenstein

Nikolaus Gravenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10283218
    Abstract: Methods and systems for patient participatory care and monitoring are provided for applications including respiratory care, ECG monitoring, capnography, infusion pump alarm prevention/management, pressure sore prevention, incentive spirometry, consciousness monitoring during sedation, pain management and other care and monitoring modalities. A patient in-the-loop system includes an input interface for receiving data acquired from a monitoring, controlling or sensing device, a storage device for storing the data at a first location, and a processor for analyzing artifacts in the data and determining whether the patient provided a deliberate action with respect to the device as a response to a prompt or query. The processor can further initiate a variety of prompts and/or output queries stored in the storage device at a second location to the patient.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: May 7, 2019
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Nikolaus Gravenstein, Samsun Lampotang, David Lizdas, Yashwant Singh Bisht
  • Publication number: 20190033313
    Abstract: The present disclosure provides methods and systems for detecting melanoma in a host. The methods include non-invasive methods of detecting melanoma and methods and systems for providing a molecular signature and/or melanoma biomarker signature for a host.
    Type: Application
    Filed: June 2, 2016
    Publication date: January 31, 2019
    Inventors: NIKOLAUS GRAVENSTEIN, CHRISTIANA M. SHAW, MICHAEL T. COSTANZO, RICK YOST, CANDICE Z. ULMER, LOUIS SEARCY
  • Publication number: 20180226142
    Abstract: Methods and systems for patient participatory care and monitoring are provided for applications including respiratory care, ECG monitoring, capnography, infusion pump alarm prevention/management, pressure sore prevention, incentive spirometry, consciousness monitoring during sedation, pain management and other care and monitoring modalities. A patient in-the-loop system includes an input interface for receiving data acquired from a monitoring, controlling or sensing device, a storage device for storing the data at a first location, and a processor for analyzing artifacts in the data and determining whether the patient provided a deliberate action with respect to the device as a response to a prompt or query. The processor can further initiate a variety of prompts and/or output queries stored in the storage device at a second location to the patient.
    Type: Application
    Filed: January 29, 2018
    Publication date: August 9, 2018
    Inventors: Nikolaus Gravenstein, Samsun Lampotang, David Lizdas, Yashwant Singh Bisht
  • Publication number: 20180140381
    Abstract: A computer-implemented method and system for guiding the placement of orthodontic brackets are provided. The system can include an at least one indexing tool designed to conform to at least a portion of a patient's teeth or alveolar process. The system can receive signals from a sensor at the indexing tool as well as signals from a sensor at a bracket positioning tool in order to track spatial location—and/or orientation of one or more brackets relative to the surface of the patient's actual or modeled teeth. A method for guiding the placement of orthodontic brackets involves detecting the location and/or orientation of a bracket with respect to at least one tooth of a patient and notifying the orthodontist that the actual bracket position and/or orientation meets specified criteria with respect to planned placement coordinates for the bracket. The method can further include collecting the planned placement coordinates for each bracket tooth combo during a planning phase.
    Type: Application
    Filed: June 27, 2016
    Publication date: May 24, 2018
    Inventors: NIKOLAUS GRAVENSTEIN, CALOGERO DOLCE, SAMSUN LAMPOTANG, DAVID ERIK LIZDAS
  • Patent number: 9962516
    Abstract: Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets in a tube, drainage tube or assembly. In one such embodiment, gas pockets are vented to inhibit excessive back-pressure or suction on an organ, vessel or cavity being drained. In another such embodiment, loops in the tubes are avoided by using a mechanical template in the form of a groove or peg assembly to thread the slack in the drainage tube to generate a monotonic gradient. In another embodiment, such as for active drainage systems, a bypass channel is provided that allows an applied vacuum to go around an obstruction created by the collection of fluid in an undrained dependent loop.
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: May 8, 2018
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Samsun Lampotang, Nikolaus Gravenstein, Wilhelm K. Schwab, David E. Lizdas, Francesca K. Enneking
  • Patent number: 9881133
    Abstract: Methods and systems for patient participatory care and monitoring are provided for applications including respiratory care, ECG monitoring, capnography, infusion pump alarm prevention/management, pressure sore prevention, incentive spirometry, consciousness monitoring during sedation, pain management and other care and monitoring modalities. A patient in-the-loop system includes an input interface for receiving data acquired from a monitoring, controlling or sensing device, a storage device for storing the data at a first location, and a processor for analyzing artifacts in the data and determining whether the patient provided a deliberate action with respect to the device as a response to a prompt or query. The processor can further initiate a variety of prompts and/or output queries stored in the storage device at a second location to the patient.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: January 30, 2018
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Nikolaus Gravenstein, Samsun Lampotang, David Lizdas, Yashwant Singh Bisht, Wilhelm K. Schwab
  • Publication number: 20180015251
    Abstract: Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets in a tube, drainage tube or assembly. In one such embodiment, gas pockets are vented to inhibit excessive back-pressure or suction on an organ, vessel or cavity being drained. In another such embodiment, loops in the tubes are avoided by using a mechanical template in the form of a groove or peg assembly to thread the slack in the drainage tube to generate a monotonic gradient. In another embodiment, such as for active drainage systems, a bypass channel is provided that allows an applied vacuum to go around an obstruction created by the collection of fluid in an undrained dependent loop.
    Type: Application
    Filed: September 28, 2017
    Publication date: January 18, 2018
    Inventors: Samsun Lampotang, Nikolaus Gravenstein, Wilhelm K. Schwab, David E. Lizdas, Francesca K. Enneking
  • Patent number: 9626805
    Abstract: An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: April 18, 2017
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Samsun Lampotang, Nikolaus Gravenstein, David Erik Lizdas, Isaac Thomas Luria
  • Publication number: 20160133056
    Abstract: An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.
    Type: Application
    Filed: December 28, 2015
    Publication date: May 12, 2016
    Inventors: Samsun LAMPOTANG, Nikolaus GRAVENSTEIN, David Erik LIZDAS, Isaac Thomas LURIA, Matthew James PETERSON
  • Patent number: 9251721
    Abstract: An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: February 2, 2016
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Samsun Lampotang, Nikolaus Gravenstein, David Erik Lizdas, Isaac Thomas Luria, Matthew James Peterson
  • Patent number: 9220475
    Abstract: Embodiments of the present invention are related to apparatus and methods for acoustically monitoring the performance of a medical device disposed within the body of a patient. According to one embodiment of an apparatus, the apparatus includes at least one acoustic sensor and a computer system that is connected to receive information from the acoustic sensor, wherein the acoustic sensor is adapted to receive a set of acoustic information that corresponds to acoustic activity within the body of said patient. The computer system is adapted for: (A) receiving the set of acoustic information, and (B) using the set of acoustic information to calculate location information relating to a location of a source of the acoustic activity.
    Type: Grant
    Filed: April 14, 2010
    Date of Patent: December 29, 2015
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Charles T. Klodell, Nikolaus Gravenstein, Wilhelm K. Schwab
  • Publication number: 20150164379
    Abstract: Embodiments of the subject invention relate to a method and apparatus for detecting and/or analyzing respiratory motion of a patient, such as an animal or person. A specific embodiment can use a radar motion detector to measure and record respiratory movements at different parts of the body, using multiple identifiable markers, such as reflectors, positioned such that movements of the patient can be monitored by monitoring the movement of the markers. As an example, the markers can be attached to or worn by the patient, inserted into the patient (such as under the skin), or otherwise positioned in a known relation to a portion or surface of the patient. In an embodiment, the identifiable reflectors are transponders with different modulation codes (in frequency, phase, amplitude, or combinations thereof) on the reflected signal.
    Type: Application
    Filed: May 23, 2013
    Publication date: June 18, 2015
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Jenshan Lin, Nikolaus Gravenstein
  • Publication number: 20150137988
    Abstract: Methods and systems for patient participatory care and monitoring are provided for applications including respiratory care, ECG monitoring, capnography, infusion pump alarm prevention/management, pressure sore prevention, incentive spirometry, consciousness monitoring during sedation, pain management and other care and monitoring modalities. A patient in-the-loop system includes an input interface for receiving data acquired from a monitoring, controlling or sensing device, a storage device for storing the data at a first location, and a processor for analyzing artifacts in the data and determining whether the patient provided a deliberate action with respect to the device as a response to a prompt or query. The processor can further initiate a variety of prompts and/or output queries stored in the storage device at a second location to the patient.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 21, 2015
    Inventors: Nikolaus Gravenstein, Samsun Lampotang, David Lizdas, Wilhelm K. Schwab, Yashwant Singh Bisht
  • Patent number: 8818472
    Abstract: Various embodiments of the present invention include devices for use in determining the concentration of a tissue energy absorber (e.g., hemoglobin) in an individual's blood. In particular embodiments, the device includes a photometric device (e.g., a pulse oximeter) and an imaging device (e.g., an ultrasound imaging device or other suitable imaging device), and the device is adapted for: (A) using the photometric device to measure a change in mass of the tissue energy absorber within a particular volume of the individual's blood between a first point in time and a second point in time, the particular volume of blood being blood within a particular portion of at least one vascular structure, the vascular structure comprising at least one of the individual's vessels (e.g.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: August 26, 2014
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Dietrich Gravenstein, Mark Rice, Samsun Lampotang, Nikolaus Gravenstein, Lori Deitte
  • Patent number: 8605133
    Abstract: The subject invention provides a panoramic, interactive, seamless, intuitive, high-resolution and yet extensive simulation tool capable of simulating dynamic events that alter the panoramic view in response to the user's actions or inaction. The dynamic panorama simulation can generate and display novel scenes that are not limited to static “canned” content that has been previously photographed, rendered, recorded, captured or filmed thus providing great flexibility, contextual authenticity and liveliness and, in some instances, unanticipated and surprising but accurate developments in the simulation.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: December 10, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Samsun Lampotang, David Erik Lizdas, John Joseph Tumino, Nikolaus Gravenstein
  • Patent number: 8544115
    Abstract: The subject invention provides materials and methods for convective and/or conductive and/or evaporative cooling of individuals, such as athletes and contestants, for safety, comfort, and enhanced performance. The materials and methods of the subject invention can, advantageously, be used to modify body core temperature or rate of change of temperature. Other uses include heating players or player parts (e.g., a kicker's leg, a pitcher's arm) in cold weather conditions.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: October 1, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Nikolaus Gravenstein, Dasia Esener, Samsun Lampotang, Michael D. Gilmore
  • Patent number: 8525666
    Abstract: Systems and methods are provided for monitoring use of handwashing agents to determine compliance with hand hygiene guidelines. A handwashing agent is provided with a detectable, volatile compound, such as odors, which is then rubbed onto a subject's hands using the subject's handwashing technique. After the handwashing event, the subject's hand is then exposed to an detector (such as a badge), which includes a sensor capable of detecting the volatile compound, and an indicator that communicates detection of the volatile compound, indicating use of the handwashing agent and hand hygiene compliance.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: September 3, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Richard J. Melker, Nikolaus Gravenstein, Donn Michael Dennis, Christopher Batich
  • Publication number: 20130172840
    Abstract: Embodiments of the invention provide methods and devices for improved drainage systems and tubing. In one embodiment, a context-sensitive flow interrupter is provided that inhibits or facilitates flow of fluid when engaged with a mating holder. In another embodiment, outflow is optimized through control of the pressure in gas pockets in a tube, drainage tube or assembly. In one such embodiment, gas pockets are vented to inhibit excessive back-pressure or suction on an organ, vessel or cavity being drained. In another such embodiment, loops in the tubes are avoided by using a mechanical template in the form of a groove or peg assembly to thread the slack in the drainage tube to generate a monotonic gradient. In another embodiment, such as for active drainage systems, a bypass channel is provided that allows an applied vacuum to go around an obstruction created by the collection of fluid in an undrained dependent loop.
    Type: Application
    Filed: September 8, 2011
    Publication date: July 4, 2013
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
    Inventors: Samsun Lampotang, Nikolaus Gravenstein, Wilhelm K. Schwab, David E. Lizdas, Francesca K. Enneking
  • Publication number: 20120280988
    Abstract: An interactive mixed reality simulator is provided that includes a virtual 3D model of internal or hidden features of an object; a physical model or object being interacted with; and a tracked instrument used to interact with the physical object. The tracked instrument can be used to simulate or visualize interactions with internal features of the physical object represented by the physical model. In certain embodiments, one or more of the internal features can be present in the physical model. In another embodiment, some internal features do not have a physical presence within the physical model.
    Type: Application
    Filed: April 8, 2011
    Publication date: November 8, 2012
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Samsun Lampotang, Nikolaus Gravenstein, David Erik Lizdas, Isaac Thomas Luria, Matthew James Peterson
  • Publication number: 20120083682
    Abstract: Embodiments of the present invention are related to apparatus and methods for acoustically monitoring the performance of a medical device disposed within the body of a patient. According to one embodiment of an apparatus, the apparatus includes at least one acoustic sensor and a computer system that is connected to receive information from the acoustic sensor, wherein the acoustic sensor is adapted to receive a set of acoustic information that corresponds to acoustic activity within the body of said patient. The computer system is adapted for: (A) receiving the set of acoustic information, and (B) using the set of acoustic information to calculate location information relating to a location of a source of the acoustic activity.
    Type: Application
    Filed: April 14, 2010
    Publication date: April 5, 2012
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Charles T. Klodell, Nikolaus Gravenstein, Wilhelm K. Schwab