Patents by Inventor Nikolaus Kaubisch

Nikolaus Kaubisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxylic acid amides and pharmaceutical compositions containing them
    Patent number: 4735959
    Abstract: There are described novel carboxylic acid derivatives of the formula ##STR1## and derivatives of the formula ##STR2## and the addition salts thereof, which exhibit an effect on the intermediary metabolism. Furthermore, the compounds of Formula Ia as well as the compounds of Formula I possess blood-sugar lowering properties.
    Type: Grant
    Filed: May 14, 1985
    Date of Patent: April 5, 1988
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Wolfgang Grell, Gerhart Griss, Robert Sauter, Rudolf Hurnaus, Eckhard Rupprecht, Nikolaus Kaubisch, Joachim Kahling, Bernhard Eisele
  • 2[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indol-5-yloxy]-2-methyl propanoic acid and hyperlipidemic or atheosclerotic use thereof
    Patent number: 4343811
    Abstract: This invention relates to novel indole derivatives of formula ##STR1## and the non-toxic, pharmacologically acceptable salts thereof. These compounds exhibit desirable pharmacological properties, especially lipid-level lowering and anti-atherosclerotic activity. The compounds of the invention may be prepared by, for example, alkylation of a corresponding hydroxy indole.
    Type: Grant
    Filed: February 29, 1980
    Date of Patent: August 10, 1982
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Rudolf Hurnaus, Gerhart Griss, Wolfgang Grell, Robert Sauter, Bernhard Eisele, Nikolaus Kaubisch, Eckhard Rupprecht, Joachim Kahling
  • Derivatives of biphenyloxy-lower alkanoic acids, salts thereof and their use as antihyperlipidemics
    Patent number: 4042711
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is straight or branched alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, phenylalkyl, phenylalkenyl, pyridyl or ##STR2## where X, Y and Z are each hydrogen, halogen, alkyl of 1 to 3 carbon atoms or alkoxy of 1 to 3 carbon atoms,R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms,A is --CO--NH-- or --NH--CO--, andn is 1, 2 or 3,And non-toxic salts thereof formed with an inorganic or organic base; the compounds as well as the salts are useful as antihyperlipidemics.
    Type: Grant
    Filed: November 11, 1976
    Date of Patent: August 16, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerhart Griss, Wolfgang Grell, Rudolf Hurnaus, Robert Sauter, Bernhard Eisele, Nikolaus Kaubisch, Matyas Leitold
  • Biphenyloxy derivatives and antihyperlipidemic use
    Patent number: 4010279
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is straight or branched alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, phenylalkyl, phenylalkenyl, pyridyl or ##STR2## where X, Y and Z are each hydrogen, halogen, alkyl of 1 to 3 carbon atoms or alkoxy of 1 to 3 carbon atoms,R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms,R.sub.3 is hydroxymethyl, carboxyl, alkoxycarbonyl of 2 to 7 carbon atoms or cycloalkoxycarbonyl or 4 to 8 carbon atoms,A is --CO--NH-- or --NH--CO--, andn is 1, 2 or 3,And, when R.sub.3 is carboxyl, non-toxic salts thereof formed with an inorganic or organic base; the compounds as well as the salts are useful as antihyperlipidemics.
    Type: Grant
    Filed: December 23, 1975
    Date of Patent: March 1, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerhart Griss, Wolfgang Grell, Rudolf Hurnaus, Robert Sauter, Bernhard Eisele, Nikolaus Kaubisch, Matyas Leitold