Patents by Inventor Nikolaus M. Gubernator

Nikolaus M. Gubernator has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydroquinoline derivatives as antithrombotic agents
    Patent number: 6825208
    Abstract: This invention relates generally to tetracyclic tetrahydroquinoline compounds, and analogues thereof, and pharmaceutically acceptable salt forms thereof, which are selective inhibitors of serine protease enzymes, especially factor VIIa; pharmaceutical compositions containing the same; and methods of using the same as anticoagulant agents for modulation of the coagulation cascade.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: November 30, 2004
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Jinglan Zhou, Leslie Robinson, Nikolaus M. Gubernator, Eddine Saiah, Xu Bai, Xin Gu
  • Tetrahydroquinoline derivatives as antithrombotic agents
    Publication number: 20030225110
    Abstract: This invention relates generally to tetracyclic tetrahydroquinoline compounds, and analogues thereof, and pharmaceutically acceptable salt forms thereof, which are selective inhibitors of serine protease enzymes, especially factor VIIa; pharmaceutical compositions containing the same; and methods of using the same as anticoagulant agents for modulation of the coagulation cascade.
    Type: Application
    Filed: August 20, 2002
    Publication date: December 4, 2003
    Inventors: Jinglan Zhou, Leslie Robinson, Nikolaus M. Gubernator, Eddine Saiah, Xu Bai, Xin Gu