Patents by Inventor Nikolaus Schmitt
Nikolaus Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11627894Abstract: A method for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device in a data processing unit, comprising receiving measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device in the data processing unit, receiving calibration data representing a time-dependent zero-signal level of the glucose sensor element in the data processing unit, determining a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero-signal level from the continuous sensor signal, and providing result data indicative of the continuous body fluid glucose level in the processing unit; and a system for determining a body fluid glucose level of a patient.Type: GrantFiled: July 16, 2015Date of Patent: April 18, 2023Assignee: Roche Diabetes Care, Inc.Inventors: Guenther Schmelzeisen-Redeker, Nikolaus Schmitt
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Patent number: 11194024Abstract: A LIDAR arrangement comprising a laser transmitter for transmitting pulses of a laser radiation to a measurement object, and a receiver for receiving pulses of the laser radiation backscattered from the measurement object, wherein the laser transmitter is configured to transmit a pulse sequence in which successive pulses respectively comprise a particular optical frequency shift to each other and wherein the receiver either includes a dispersive element for separating the pulses in time depending on the optical frequency by a frequency-based deflection, and a position resolution optical matrix transmitter on which the pulses separated in time by the dispersive element are mapped, or includes a frequency analyzer for the frequency-based separation of the pulses by superimposition with a reference radiation.Type: GrantFiled: July 12, 2018Date of Patent: December 7, 2021Assignee: Airbus Defence and Space GmbHInventors: Nikolaus Schmitt, Thorsteinn Halldorsson
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Patent number: 10791969Abstract: The present disclosure refers to a method for determining a blood glucose level for a patient, the method comprising detecting a present sensor signal in a present continuous interstitial blood glucose measurement for a patient; providing measurement data representing the present sensor signal; providing sensor signal correction data representing a patient-specific signal correction, the sensor signal correction data being determined from a former interstitial blood glucose measurement for the patient and comprising at least one of time delay data representing a patient-specific time delay ?t between a blood glucose value measured in a continuous interstitial blood glucose measurement and a blood glucose reference value measured in a capillary blood glucose measurement, and sensor sensitivity data representing, for the patient, a patient-specific sensor sensitivity for the sensor, determining corrected measurement data representing a corrected present sensor signal by applying the sensor signal correction datType: GrantFiled: June 20, 2017Date of Patent: October 6, 2020Assignee: ROCHE DIABETES CARE, INCInventors: Guenther Schmelzeisen-Redeker, Nikolaus Schmitt, Christian Ringemann
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Patent number: 10289652Abstract: A method for operating measuring equipment for detecting at least one analyte in a bodily fluid by means of at least one continuously measuring blood glucose sensor. At least one calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises at least one measurement signal from the measuring equipment and at least one reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method, more particularly using a formation of at least one median, is used to determine at least one probable slope from the plurality of possible slopes. Furthermore, at least one measurement is carried out.Type: GrantFiled: November 18, 2015Date of Patent: May 14, 2019Assignee: Roche Diabetes Care, Inc.Inventors: Nikolaus Schmitt, Gerhard Frisch
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Publication number: 20190018115Abstract: A LIDAR arrangement comprising a laser transmitter for transmitting pulses of a laser radiation to a measurement object, and a receiver for receiving pulses of the laser radiation backscattered from the measurement object, wherein the laser transmitter is configured to transmit a pulse sequence in which successive pulses respectively comprise a particular optical frequency shift to each other and wherein the receiver either includes a dispersive element for separating the pulses in time depending on the optical frequency by a frequency-based deflection, and a position resolution optical matrix transmitter on which the pulses separated in time by the dispersive element are mapped, or includes a frequency analyzer for the frequency-based separation of the pulses by superimposition with a reference radiation.Type: ApplicationFiled: July 12, 2018Publication date: January 17, 2019Inventors: Nikolaus Schmitt, Thorsteinn Halldorsson
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Publication number: 20170319112Abstract: The present disclosure refers to a method for determining a blood glucose level for a patient, the method comprising detecting a present sensor signal in a present continuous interstitial blood glucose measurement for a patient; providing measurement data representing the present sensor signal; providing sensor signal correction data representing a patient-specific signal correction, the sensor signal correction data being determined from a former interstitial blood glucose measurement for the patient and comprising at least one of time delay data representing a patient-specific time delay ?t between a blood glucose value measured in a continuous interstitial blood glucose measurement and a blood glucose reference value measured in a capillary blood glucose measurement, and sensor sensitivity data representing, for the patient, a patient-specific sensor sensitivity for the sensor, determining corrected measurement data representing a corrected present sensor signal by applying the sensor signal correction datType: ApplicationFiled: June 20, 2017Publication date: November 9, 2017Applicant: Roche Diabetes Care, Inc.Inventors: Guenther Schmelzeisen-Redeker, Nikolaus Schmitt, Christian Ringemann
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Publication number: 20170156647Abstract: A method for determining a body fluid glucose level of a patient from a continuous signal of a glucose sensor element of a continuous body fluid glucose monitoring device in a data processing unit, comprising receiving measurement data representing a continuous sensor signal provided by a glucose sensor element of a continuous body fluid glucose monitoring device in the data processing unit, receiving calibration data representing a time-dependent zero-signal level of the glucose sensor element in the data processing unit, determining a body fluid glucose level by processing at least the measurement data and the calibration data in the data processing unit, the processing comprising subtraction of the time dependent zero- signal level from the continuous sensor signal, and providing result data indicative of the continuous body fluid glucose level in the processing unit; and a system for determining a body fluid glucose level of a patient.Type: ApplicationFiled: July 16, 2015Publication date: June 8, 2017Applicant: Roche Diabetes Care, Inc.Inventors: Guenther SCHMELZEISEN-REDEKER, Nikolaus SCHMITT
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Patent number: 9383447Abstract: The invention relates to a method for light detecting and ranging (LIDAR) measurement of speeds, in which a laser beam is directed at the medium to be measured, and radiation which is subsequently emitted from the medium (16) is measured by a detector. In order to optimize the measurement, a spatial measurement range can be selected by activation and/or deactivation of the detector for at least one predetermined or regulated time duration of less than about 500 ?s after emission of a laser pulse to the medium to be measured. Furthermore, a direct reception Doppler LIDAR apparatus can be used to perform the method.Type: GrantFiled: June 30, 2009Date of Patent: July 5, 2016Assignee: EADS Deutschland GmbHInventors: Nikolaus Schmitt, Wolfgang Rehm, Thomas Pistner
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Publication number: 20160070675Abstract: A method for operating measuring equipment for detecting at least one analyte in a bodily fluid by means of at least one continuously measuring blood glucose sensor. At least one calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises at least one measurement signal from the measuring equipment and at least one reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method, more particularly using a formation of at least one median, is used to determine at least one probable slope from the plurality of possible slopes. Furthermore, at least one measurement is carried out.Type: ApplicationFiled: November 18, 2015Publication date: March 10, 2016Inventors: Nikolaus Schmitt, Gerhard Frisch
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Patent number: 9222951Abstract: A method for operating measuring equipment for detecting an analyte in a bodily fluid by means of a continuously measuring blood glucose sensor. A calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises a measurement signal from the measuring equipment and a reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method using a formation of at least one median is used to determine a probable slope from the plurality of possible slopes. Furthermore, a measurement is carried out. During the measurement and using the probable slope, a concentration of the analyte in the bodily fluid is deduced from a measurement signal from the measuring equipment and the probable slope.Type: GrantFiled: February 27, 2012Date of Patent: December 29, 2015Assignee: Roche Diabetes Care, Inc.Inventors: Nikolaus Schmitt, Gerhard Frisch
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Patent number: 8675184Abstract: The invention relates to a method for Doppler light detection and ranging (LIDAR) measurement of speeds. A laser beam is directed at the medium to be measured, and radiation which is then emitted by the medium is measured by a detector. In order to allow better control of the dynamic range of a direct reception Doppler LIDAR apparatus, a multiplicity of laser pulses can be transmitted per measurement, and a multiplicity of laser pulses can be received by the detector per measurement. A direct reception Doppler LIDAR apparatus can be suitable for carrying out the method.Type: GrantFiled: June 30, 2009Date of Patent: March 18, 2014Assignee: EADS Deutschland GmbHInventors: Nikolaus Schmitt, Wolfgang Rehm, Thomas Pistner
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Patent number: 8589106Abstract: A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.Type: GrantFiled: December 22, 2010Date of Patent: November 19, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Timothy Peter Engelhardt, Nikolaus Schmitt, Phillip E. Pash, David Duke, Abhishek Soni
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Publication number: 20120191362Abstract: A method for operating measuring equipment for detecting an analyte in a bodily fluid by means of a continuously measuring blood glucose sensor. A calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises a measurement signal from the measuring equipment and a reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method, using a formation of at least one median is used to determine a probable slope from the plurality of possible slopes. Furthermore, a measurement is carried out. During the measurement and using the probable slope, a concentration of the analyte in the bodily fluid is deduced from a measurement signal from the measuring equipment and the probable slope.Type: ApplicationFiled: February 27, 2012Publication date: July 26, 2012Inventors: Nikolaus Schmitt, Gerhard Frisch
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Publication number: 20120166126Abstract: A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.Type: ApplicationFiled: December 22, 2010Publication date: June 28, 2012Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Timothy Peter Engelhardt, Nikolaus Schmitt, Phillip E. Pash, David Duke, Abhishek Soni
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Publication number: 20110188029Abstract: The invention relates to a method for Doppler light detection and ranging (LIDAR) measurement of speeds. A laser beam is directed at the medium to be measured, and radiation which is then emitted by the medium is measured by a detector. In order to allow better control of the dynamic range of a direct reception Doppler LIDAR apparatus, a multiplicity of laser pulses can be transmitted per measurement, and a multiplicity of laser pulses can be received by the detector per measurement. A direct reception Doppler LIDAR apparatus can be suitable for carrying out the method.Type: ApplicationFiled: June 30, 2009Publication date: August 4, 2011Applicant: EADS DEUTSCHLAND GMBHInventors: Nikolaus Schmitt, Wolfgang Rehm, Thomas Pistner
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Publication number: 20110181864Abstract: The invention relates to a method for light detecting and ranging (LIDAR) measurement of speeds, in which a laser beam is directed at the medium to be measured, and radiation which is subsequently emitted from the medium (16) is measured by a detector. In order to optimize the measurement, a spatial measurement range can be selected by activation and/or deactivation of the detector for at least one predetermined or regulated time duration of less than about 500 ?s after emission of a laser pulse to the medium to be measured. Furthermore, a direct reception Doppler LIDAR apparatus can be used to perform the method.Type: ApplicationFiled: June 30, 2009Publication date: July 28, 2011Applicant: EADS DEUTSCHLAND GMBHInventors: Nikolaus Schmitt, Wolfgang Rehm, Thomas Pistner
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Patent number: 6282227Abstract: In a diode-pumped frequency-doubled solid-state laser, all the elements of the resonator as well as the elements inside the resonator such as the laser crystal, mirror, and frequency doubler, are accommodated in or on an angle or U profile, which is milled as a solid part from a solid piece or is manufactured as a cast, stamped, or sintered part from metal or ceramic. The profile has one or more intermediate walls that are made of the same piece, as the angle or U profile to lend additional stability. The elements of the resonator or elements inside the resonator are contained on or in the resonator, and the intermediate walls have openings to allow the laser mode and/or the laser irradiation to pass through.Type: GrantFiled: September 21, 1999Date of Patent: August 28, 2001Assignee: EADS Deutschland GmbHInventors: Nikolaus Schmitt, Guenter Toesko, Guenter Reithmeier, Josef Schalk
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Patent number: 6125130Abstract: The invention concerns a method of reducing the amplitude noise of solid lasers (e.g. Nd-YAG, Nd:YAlO, Nd:YLF, Nd:YVO.sub.3, etc.) with resonator-internal frequency doubling (for example by KTP, LBO, BBO, KNbO3, LiNbO.sub.3, etc.). According to the invention, some of the frequency-doubled ejected laser radiation or the fundamental wave radiation is guided onto a photodetector (in particular a photodiode) whose electrical output signal undergoes bandpass filtering which filters out a frequency range typical of the noise. This output signal, optionally after rectification, quadrature and/or integration, is then subjected to temperature regulation or control which corrects the temperature of the frequency-doubling crystal such that the output signal is minimized after the bandpass filter and thus the amplitude noise of the laser radiation is minimized.Type: GrantFiled: April 7, 1999Date of Patent: September 26, 2000Inventors: Nikolaus Schmitt, Gunter Toesko, Josef Schalk, Susanne Nikolov
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Patent number: 5894489Abstract: A laser system generates read, green and blue beams from a single laser beam generated by an IR continuous-wave laser using rare-earth or transition elements. Semiconductor diodes are used to excite IR continuous-wave laser and simple passive non-linear frequency conversion is used to generate the red, green and blue effective beams.Type: GrantFiled: November 17, 1997Date of Patent: April 13, 1999Assignee: Daimler-Benz AGInventors: Thorsteinn Halldorsson, Max Koniger, Axel Mehnert, Peter Peuser, Gunter Reithmeier, Nikolaus Schmitt, Paul Zeller, Alois Seilmeier, Heinrich Graener
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Patent number: 5637885Abstract: The invention relates to a method for producing a microsystem and from it forming a microsystem laser, which preferably has a vertical structural element by contacting of wafer plates, which carry different functional elements of a system, so that this system on the one hand thus includes heterogeneous functions such as actuators, optics, sensors, cooling systems, micromechanics and electronics, and on the other hand, the wafer carrying these functions permits a relatively homogeneous processing of quite similar functions integrated each on one wafer, so that the complexity of the system is created for the first time for the vertical arrangement of these functions.Type: GrantFiled: April 7, 1995Date of Patent: June 10, 1997Assignee: Deutsche Aerospace AGInventors: Stefan Heinemann, Axel Mehnert, Peter Peuser, Nikolaus Schmitt, Helmut Seidel