Patents by Inventor Nikolay Khanzhin

Nikolay Khanzhin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted thiomorpholine derivatives
    Patent number: 8012962
    Abstract: The present invention relates to thiomorpholine derivatives of formula I or pharmaceutically acceptable salts thereof and their use in treating seizure disorders, anxiety disorders, bipolar disorders, neuropathic pain disorders and migraine pain disorders.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: September 6, 2011
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • Pyridone derivatives as NK3 antagonists
    Publication number: 20110144164
    Abstract: The present invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.
    Type: Application
    Filed: December 14, 2010
    Publication date: June 16, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Nikolay Khanzhin, Søren Møller Nielsen, Karsten Juhl, Lars Kyhn Rasmussen
  • ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS
    Publication number: 20110130420
    Abstract: Isoquinolone derivatives of the general formula Ik? are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia.
    Type: Application
    Filed: April 22, 2009
    Publication date: June 2, 2011
    Inventors: Nikolay Khanzhin, Karsten Juhl, Soren Moller Nielsen, Klaus Baek Simonsen
  • ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS
    Publication number: 20110130407
    Abstract: Isoquinolone derivatives of the general formula I are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia.
    Type: Application
    Filed: June 19, 2009
    Publication date: June 2, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Nikolay Khanzhin, Karsten Juhl, Søren Møller Nielsen, Klaus Baek Simonsen
  • Substituted p-diaminobenzene derivatives
    Patent number: 7906537
    Abstract: The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: March 15, 2011
    Assignee: H. Lundbeck A/S
    Inventors: Nikolay Khanzhin, Mario Rottlander, Andreas Ritzen, William P. Watson
  • SUBSITUTED PYRIDINE DERIVATIVES
    Publication number: 20110003811
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Application
    Filed: September 14, 2010
    Publication date: January 6, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornøe, Nikolay Khanzhin, Mario Rottländer, William Patrick Watson, Daniel Rodriguez Greve
  • Methods of using substituted morpholine derivatives
    Patent number: 7812023
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: October 12, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • Substituted pyridine derivatives
    Patent number: 7812020
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: October 12, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Nikolay Khanzhin, Mario Rottländer, William Patrick Watson, Daniel Rodriguez Greve
  • SUBSTITUTED PYRIMIDINE DERIVATIVES
    Publication number: 20100137311
    Abstract: The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.
    Type: Application
    Filed: January 30, 2010
    Publication date: June 3, 2010
    Applicant: H. LUNDBECK A/S
    Inventors: Nikolay Khanzhin, Daniel Rodriguez Greve, Mario Rottländer
  • ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS
    Publication number: 20100076016
    Abstract: The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.
    Type: Application
    Filed: September 11, 2009
    Publication date: March 25, 2010
    Applicant: H. LUNDBECK A/S
    Inventors: Nikolay Khanzhin, Karsten Juhl, Soren Moller Nielsen, Klaus Baek Simonsen
  • Substituted pyrimidine derivatives
    Patent number: 7683058
    Abstract: The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: March 23, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Nikolay Khanzhin, Daniel Rodriguez Greve, Mario Rottländer
  • Methods of using substituted morpholine derivatives
    Publication number: 20100063033
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 5, 2009
    Publication date: March 11, 2010
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • SUBSTITUTED ANILINE DERIVATIVES
    Publication number: 20100063044
    Abstract: The present invention relates to aniline derivatives of formula I: wherein R1, R2, R3, R4, Z and q are as defined herein; or salts thereof and their use.
    Type: Application
    Filed: August 17, 2009
    Publication date: March 11, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlãnder, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Publication number: 20100063036
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 3, 2009
    Publication date: March 11, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Patent number: 7632835
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: December 15, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • Substituted aniline derivatives
    Patent number: 7601870
    Abstract: The present invention relates to aniline derivatives of the general formula I or salts thereof, described therein, and their use.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: October 13, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS
    Publication number: 20090143402
    Abstract: Isoquinolone derivatives of the general formula are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia.
    Type: Application
    Filed: April 11, 2008
    Publication date: June 4, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Klaus Baek Simonsen, Jan Kehler, Karsten Juhl, Nikolay Khanzhin, Soren Moller Nielsen
  • METHODS OF USING SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
    Publication number: 20090143369
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: January 28, 2009
    Publication date: June 4, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
    Publication number: 20090137571
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: January 28, 2009
    Publication date: May 28, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • USE OF KCNQ-OPENERS FOR TREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA
    Publication number: 20090118285
    Abstract: The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symptoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.
    Type: Application
    Filed: February 2, 2007
    Publication date: May 7, 2009
    Applicant: H. Lundbeck A/S
    Inventors: Henriette Husum Bak-Jensen, Christian Wenzel Tornoe, Mario Rottlander, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson