Patents by Inventor Nikolay S. Zefirov

Nikolay S. Zefirov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEANS FOR IMPROVING COGNITIVE FUNCTIONS AND MEMORY BASED ON HYDROGENATED PYRIDO(4,3-B)INDOLES (VARIANTS), PHARMACOLOGICAL MEANS BASED THEREON AND METHOD FOR THE USE THEREOF
    Publication number: 20100286188
    Abstract: A means for improving cognitive functions and memory based on hydrogenated pyrido (4,3-b) indoles (variants), a pharmacological means based thereon and a method for the use thereof relate to the use of chemical compounds in the field of medicine and may be used to extend the arsenal of means which can be utilized for substantial enhancement of memory and activation of the learning process, for the treatment of impaired cognitive functions and memory in the elderly and in mild cognitive impairment, in brain trauma, in chronic cerebrovascular insufficiency, in hypoxic encephalopathies, resulting from chronic alcoholism and in delayed development in children. Said task is resolved by the use of hydrogenated pyrido ([4, 3-b]) indoles of formula (1) or formula (2) as means for improving cognitive functions and memory.
    Type: Application
    Filed: November 30, 2007
    Publication date: November 11, 2010
    Inventors: Sergey O. Bachurin, Svetlana I. Gavrilova, Vladimir V. Grigoriev, Bogdan K. Beznosko, Nikolay S. Zefirov
  • Agents for treating neurodegenerative disorders
    Patent number: 7071206
    Abstract: Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided. The compounds that are provided for the treatment of neurodegenerative diseases can be represented by a general formula (I): wherein R1 is Me, Et or PhCH2; R2 is H, PhCH2 or 6-Me-3-Py-(CH2)2; and R3 is H, Me or Br. The solid line accompanied by the dotted line i.e. represents a single or double bond and salts thereof with pharmacologically acceptable acids and quaternary derivatives.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: July 4, 2006
    Assignee: Medivation, Inc.
    Inventors: Nikolai S. Zefirov, Andrei Z. Afanasiev, Svetlana V. Afanasieva, Sergei O. Bachurin, Sergei E. Tkachenko, Vladmir V. Grigoriev, Marina A. Jurovskaya, Valery P. Chetverikov, Elizaveta E. Bukatina, Irina V. Grigorieva
  • 5-methoxy-carbonylamino-N-acetyltryptamine compounds and derivates thereof
    Patent number: 6849654
    Abstract: Compositions comprising 5-methoxy-carbonylamino-N-acetyltryptamine compounds and derivatives thereof for the treatment of depression are disclosed.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: February 1, 2005
    Assignee: Caritas St. Elizabeth's Medical Center of Boston, Inc.
    Inventors: Gregory F. Oxenkrug, Nikolai S. Zefirov, Sergey O. Bachurin
  • Agent for treating neurodegenerative disorders
    Publication number: 20040044022
    Abstract: Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided.
    Type: Application
    Filed: August 28, 2003
    Publication date: March 4, 2004
    Inventors: Nikolai S. Zefirov, Andrei Z. Afanasiev, Svetlana V. Afanasieva, Sergei O. Bachurin, Sergei E. Tkachenko, Vladimir V. Grigoriev, Marina A. Jurovskaya, Valery P. Chetverikov, Elizaveta E. Bukatina, Irina V. Grigorieva
  • Agents for treating neurodegenerative disorders
    Publication number: 20020115682
    Abstract: Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided.
    Type: Application
    Filed: January 23, 2002
    Publication date: August 22, 2002
    Inventors: Nikolai S. Zefirov, Andrei Z. Afanasiev, Svetlana V. Afanasieva, Sergei O. Bachurin, Sergei E. Tkachenko, Vladimir V. Grigoriev, Marina A. Jurovskaya, Valery P. Chetverikov, Elizaveta E. Bukatina, Irina V. Grigorieva
  • Agents for treating neurodegenerative disorders
    Publication number: 20010020028
    Abstract: Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided.
    Type: Application
    Filed: February 6, 2001
    Publication date: September 6, 2001
    Inventors: Nikolai S. Zefirov, Andrei Z. Afanasiev, Svetlana V. Afanasieva, Sergei O. Bachurin, Sergei E. Tkachenko, Vladimir V. Grigoriev, Marina A. Jurovskaya, Valery P. Chetverikov, Elizaveta E. Bukatina, Irina V. Grigorieva
  • Agent for treating neurodegenerative disorders
    Patent number: 6187785
    Abstract: Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided. The compounds that are provided for the treatment of neurodegenerative diseases can be represented by a general formula (I): wherein R1 is Me, Et or PhCH2; R2 is H, PhCH2 or 6-Me-3-Py—(CH2)2; and R3 is H, Me or Br. The solid line accompanied by the dotted line, i.e. — represents a single or double bond and salts thereof with pharmacologically acceptable acids and quaternary derivatives.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: February 13, 2001
    Assignee: Selena Pharmaceuticals, Inc.
    Inventors: Nikolai S. Zefirov, Andrei Z. Afanasiev, Svetlana V. Afanasieva, Sergei O. Bachurin, Sergei E. Tkachenko, Vladimir V. Grigoriev, Marina A. Jurovskaya, Valery P. Chetverikov, Elizaveta E. Bukatina, Irina V. Grigorieva