Patents by Inventor Nikolay Turovets

Nikolay Turovets has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250000774
    Abstract: Disclosed herein are compositions and methods of using a topical formulation on lips and nails. The topical formulation might comprise one for more defensins. The topical formulation might also comprise other cosmetically acceptable ingredients. The topical formulation might be used to alleviate a cosmetic concern of the lips or nails.
    Type: Application
    Filed: June 26, 2024
    Publication date: January 2, 2025
    Inventor: Nikolay Turovets
  • Patent number: 12115241
    Abstract: Compositions and methods for darkening hair of intact skin are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied formulation. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided.
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: October 15, 2024
    Inventor: Nikolay Turovets
  • Patent number: 11806384
    Abstract: Compositions for topical treatment to reduce the appearance of the hyperpigmented lesions of melasma are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied gel, lotion, wash, shampoo, cream, or mask. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: November 7, 2023
    Assignee: MEDICELL TECHNOLOGIES, LLC
    Inventor: Nikolay Turovets
  • Patent number: 11744856
    Abstract: Pharmaceutical and cosmetic compositions and methods are presented that have a carrier in combination with a media composition that is derived from distinct cell cultures. The distinct cell cultures are obtained from growing different cells that are distinct with respect to at least one of cell type, cell age, cell differentiation stage, and physiological condition. Thus, the composite medium will provide mediator molecules that are ordinarily not founds in their combination and that can be fine tuned to specific purposes.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 5, 2023
    Assignee: MediCell Technologies, LLC
    Inventors: Nikolay Turovets, Christopher B. Adams
  • Publication number: 20230000749
    Abstract: The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.
    Type: Application
    Filed: September 9, 2022
    Publication date: January 5, 2023
    Inventors: Nikolay Turovets, William B. Adams
  • Publication number: 20230000751
    Abstract: The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.
    Type: Application
    Filed: September 9, 2022
    Publication date: January 5, 2023
    Inventors: Nikolay Turovets, William B. Adams
  • Publication number: 20230000750
    Abstract: The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.
    Type: Application
    Filed: September 9, 2022
    Publication date: January 5, 2023
    Inventors: Nikolay Turovets, William B. Adams
  • Publication number: 20220401337
    Abstract: The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.
    Type: Application
    Filed: July 29, 2022
    Publication date: December 22, 2022
    Inventors: Nikolay Turovets, William B. Adams
  • Patent number: 11491096
    Abstract: The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: November 8, 2022
    Assignee: MEDICELL TECHNOLOGIES, LLC
    Inventors: Nikolay Turovets, William B. Adams
  • Patent number: 11260013
    Abstract: Compositions and methods for topical treatment of hair loss in otherwise normal skin that is affected by alopecia are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied gel, lotion, wash, shampoo, cream, or mask. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided. Such compositions and methods can be used in conjunction with traditional methods for treatment of hair loss.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: March 1, 2022
    Assignee: MediCell Technologies, LLC
    Inventor: Nikolay Turovets
  • Patent number: 11020452
    Abstract: Compositions and methods for topical treatment of the hyperpigmented lesions of melasma are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied gel, lotion, wash, shampoo, cream, or mask. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: June 1, 2021
    Assignee: Medicell Technologies, LLC
    Inventor: Nikolay Turovets
  • Patent number: 8986995
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: March 24, 2015
    Assignee: International Stem Cell Corporation
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus
  • Publication number: 20130045534
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Application
    Filed: September 14, 2012
    Publication date: February 21, 2013
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus
  • Patent number: 8268621
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: September 18, 2012
    Assignee: International Stem Cell Corporation
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus
  • Publication number: 20120100110
    Abstract: The disclosure provides methods for isolating a pure or enriched population of differentiated cells derived from stem cells, comprising differentiating the population of stem cells; and migrating the differentiated cells through a porous membrane in a differentiation device to isolate the pure or enriched population of differentiated cells. The disclosure also provides a differentiation device for isolating a pure or enriched population of differentiated cells derived from stem cells, the device comprising a porous membrane; and an extracellular matrix.
    Type: Application
    Filed: April 19, 2011
    Publication date: April 26, 2012
    Applicant: INTERNATIONAL STEM CELL CORPORATION
    Inventors: Nikolay Turovets, Andrey Semechkin, Larissa Agapova, Jeffrey Janus
  • Publication number: 20100173414
    Abstract: The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells.
    Type: Application
    Filed: December 2, 2009
    Publication date: July 8, 2010
    Applicant: INTERNATIONAL STEM CELL CORPORATION
    Inventors: Nikolay Turovets, Larisa Agapova, Andrey Semechkin, Jeffrey Janus