Patents by Inventor Nikolay V. PLOTNIKOV

Nikolay V. PLOTNIKOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARBOXYESTERASE BIOCATALYSTS
    Publication number: 20230193227
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Application
    Filed: October 13, 2022
    Publication date: June 22, 2023
    Inventors: Kristin K. Brown, Brent M. Dorr, Douglas E. Fuerst, Katherine Joyce Honicker, Lydia Sanchez Jordan, James Patrick Morrison, Nikolay V. Plotnikov, Markus Schober, Rama Voladri
  • HTT MODULATORS FOR TREATING HUNTINGTON'S DISEASE
    Publication number: 20230159531
    Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.
    Type: Application
    Filed: November 16, 2022
    Publication date: May 25, 2023
    Inventors: Longbin Liu, Celia Dominguez, Nikolay V. Plotnikov, Alan Haughan, Andrew Stott, Brett Cosgrove, Cole Clissold, Huw Vater, Jonathan Spencer, William Esmieu, Karine Malagu, Mark Chambers
  • Carboxyesterase biocatalysts
    Patent number: 11535833
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: December 27, 2022
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Kristin K. Brown, Brent M. Dorr, Douglas E. Fuerst, Katherine Joyce Honicker, Lydia Sanchez Jordan, James Patrick Morrison, Nikolay V. Plotnikov, Markus Schober, Rama Voladri
  • CARBOXYESTERASE BIOCATALYSTS
    Publication number: 20210115417
    Abstract: The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 22, 2021
    Inventors: Kristin K. BROWN, Brent M. DORR, Douglas E. FUERST, Katherina Joyce HONICKER, Lydia Sanchez JORDAN, James Patrick MORRISON, Nikolay V. PLOTNIKOV, Markus SCHOBER, Rama VOLADRI