Patents by Inventor Nikolche GJOREVSKI

Nikolche GJOREVSKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Assessing a Compound Interacting with a Target on Epithelial Cells
    Publication number: 20210003559
    Abstract: Disclosed herein is a method for assessing a compound interacting with a target on polarized epithelial cells. The method comprising the steps of providing an organ chip comprising a main channel and polarized epithelial cells, wherein the main channel is divided into an apical channel and a basal channel separated by the polarized epithelial cells, wherein the apical side of the polarized epithelial cells is directed towards the apical channel and the basolateral side of the polarized epithelial cells is directed towards the basal channel. Determining the localization and optionally the expression level of the target on the polarized epithelial cells.
    Type: Application
    Filed: June 25, 2020
    Publication date: January 7, 2021
    Inventors: Cristina Bertinetti-Lapatki, Lauriane Cabon, Adrian B. Roth, Annie Moisan, Nikolche Gjorevski, Jordan S. Kerns, Geraldine A. Hamilton, Catherine Karalis, Heather Grant, Riccardo Barrile, Debora Barreiros Petropolis, Chaitra Belgur
  • ORGANOID TISSUE ENGINEERING
    Publication number: 20190367872
    Abstract: The invention relates to methods for developing and maintaining organoids and the organoids produced thereby.
    Type: Application
    Filed: November 17, 2017
    Publication date: December 5, 2019
    Inventors: Matthias LUTOLF, Nikolche GJOREVSKI, Mike NIKOLAEV, Sara GERALDO, Nathalie BRANDENBERG, Yoji TABATA