Patents by Inventor Nikunj Shambhubhai Kachhadia

Nikunj Shambhubhai Kachhadia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of bendamustine hydrochloride
    Patent number: 9643932
    Abstract: The present invention relates to an improved process for the synthesis of bendamustine, in particular, bendamustine hydrochloride of the formula (VI) and its intermediate 1-methyl-5-[bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]lithium butanoate of formula (V), both having a purity of ?99%, which is simple, convenient, economical, does not use hazardous chemicals and is industrially viable.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 9, 2017
    Assignee: Fresenius Kabi Oncology Limited
    Inventors: Bhuwan Bhaskar Mishra, Nikunj Shambhubhai Kachhadia, Vinod Singh Tomar, Saswata Lahiri
  • Process for the preparation of bendamustine hydrochloride
    Patent number: 9108924
    Abstract: The present invention relates to an improved process for the synthesis of bendamustine, in particular, bendamustine hydrochloride of the formula (VI) and its intermediate 1-methyl-5-[bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]lithium butanoate of formula (V), both having a purity of ?99%, which is simple, convenient, economical, does not use hazardous chemicals and is industrially viable.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: August 18, 2015
    Assignee: Fresenius Kabi Oncology Limited
    Inventors: Bhuwan Bhaskar Mishra, Nikunj Shambhubhai Kachhadia, Vinod Singh Tomar, Saswata Lahiri
  • PROCESS FOR THE PREPARATION OF BENDAMUSTINE HYDROCHLORIDE
    Publication number: 20150105561
    Abstract: The present invention relates to an improved process for the synthesis of bendamustine, in particular, bendamustine hydrochloride of the formula (VI) and its intermediate 1-methyl-5-[bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]lithium butanoate of formula (V), both having a purity of ?99%, which is simple, convenient, economical, does not use hazardous chemicals and is industrially viable.
    Type: Application
    Filed: December 19, 2014
    Publication date: April 16, 2015
    Inventors: Bhuwan Bhaskar Mishra, Nikunj Shambhubhai Kachhadia, Vinod Singh Tomar, Saswata Lahiri