Patents by Inventor Nils A. Nilsson

Nils A. Nilsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9309267
    Abstract: The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: April 12, 2016
    Assignee: AstraZeneca AB
    Inventors: Seth Björk, Peter Johnström, Nils A. Nilsson, Katinka Ruda, Per M. Schou, Britt-Marie Swahn, Vern Delisser
  • Publication number: 20140296534
    Abstract: The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form.
    Type: Application
    Filed: January 7, 2014
    Publication date: October 2, 2014
    Applicant: AstraZeneca AB
    Inventors: Seth Björk, Peter Johnström, Nils A. Nilsson, Katinka Ruda, Per M. Schou, Britt-Marie Swahn, Vern Delisser
  • Patent number: 4894221
    Abstract: Novel morpholino compounds having the general formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R.sub.2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, the sum of the carbon atoms in the groups R.sub.1 and R.sub.2 being at least 10 and preferably 10 to 20; and pharmaceutically acceptable salts thereof. Compositions for the treatment of the oral cavity and especially the tooth surfaces containing the novel compound or a salt thereof, preferably from 0.1 to 5% by weight thereof. Use of the compounds to inhibit the formation of dental plaque or remove plaque already formed by application of the compound in an aqueous solution or a composition to the surfaces of the oral cavity, especially the surfaces of the teeth. Processes for the preparation of the compounds.
    Type: Grant
    Filed: March 30, 1983
    Date of Patent: January 16, 1990
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Nils A. Nilsson, Willard Lars-Olof
  • Patent number: 4636382
    Abstract: Novel morpholino compounds having the general formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R.sub.2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, the sum of the carbon atoms in the groups R.sub.1 and R.sub.2 being at least 10 and preferably 10 to 20; and pharmaceutically acceptable salts thereof. Compositions for the treatment of the oral cavity and especially the tooth surfaces containing the novel compound or a salt thereof, preferably from 0.1 to 5% by weight thereof. Use of the compounds to inhibit the formation of dental plaque or remove plaque already formed by application of the compound in an aqueous solution or a composition to the surfaces of the oral cavity, especially the surfaces of the teeth. Processes for the preparation of the compounds.
    Type: Grant
    Filed: February 14, 1985
    Date of Patent: January 13, 1987
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Nils A. Nilsson, Lars-Olof Willard
  • Patent number: 4466676
    Abstract: Arrangement for cabinet with a door which can be opened at either of two opposing edges. At each of the opposing edges the door is hingedly connected with a side flap which when opened permits access to material stored in the cabinet. Each side flap is capable of being locked to the cabinet by means of two locking devices. When an arbitrary pair of locking devices is unlocked the door together with one side flap can be swung outwards from the cabinet.
    Type: Grant
    Filed: May 2, 1983
    Date of Patent: August 21, 1984
    Assignee: Forenade Fabriksverken
    Inventor: Nils A. Nilsson
  • Patent number: 4144320
    Abstract: Aminoalcohol compounds and acid addition salts thereof, useful in the prevention and treatment of dental caries and periodontitis, are disclosed. Methods of preparing said derivatives, orally acceptable compositions containing said compounds, and a method of treatment therewith are also disclosed.
    Type: Grant
    Filed: April 12, 1977
    Date of Patent: March 13, 1979
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Nils A. Nilsson, Lars-Olof Willard