Abstract: A chromatography column for effecting chromatographic separation of at least two components of a sample flowing through the column. The column comprises a housing and at least one solid stationary phase within the housing. The stationary phase has chromatographic functionality and is effective for chromatographic separation. Means are provided for distributing the sample through the stationary phase and for collecting the sample after the sample has flowed through the stationary phase. The stationary phase comprises:(a) a plurality of layers of swellable fibrous matrix in sheet form having chromatographic functionality and being effective for chromatographic separation; and(b) a spacer means between each layer for permitting controlled swelling thereof and enhancing the distribution of sample flowing through the stationary phase.

Abstract: A chromatography column for effecting chromatographic separation of at least two components of a sample flowing through the column. The column comprises a housing and at least one solid stationary phase within the housing. The stationary phase has chromatographic functionality and is effective for chromatographic separation. Means are provided for distributing the sample through the stationary phase and for collecting the sample after the sample has flowed through the stationary phase. The stationary phase comprises:(a) a plurality of layers of swellable fibrous matrix in sheet form having chromatographic functionality and being effective for chromatographic separation; and(b) a spacer means between each layer for permitting controlled swelling thereof and enhancing the distribution of sample flowing through the stationary phase.

Abstract: A multicartridge chromatography cartridge housing for use in supporting several chromatography cartridges in a parallel array is disclosed. A number of elongated cylindrical cartridge holders extend between a lower support plate and an upper support plate. Each such cartridge holder receives a chromatography cartridge which is held within the holder by suitable end caps and tie rods. Several truss rods serve to space the support plates from each other and to support the housing assembly. Fluid flow manifolds are secured to the lower and upper support plates and serve to distribute the fluid to, and consolidate the fluid received from the cartridges within the individual holders. The multicartridge chromatography cartridge housing in accordance with the present invention handles high fluid flow volumes with a small pressure drop and with a minimum hold up volume.