Patents by Inventor Nils Johansen

Nils Johansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Osteogenic Growth Peptide Fusion Proteins
    Publication number: 20080064630
    Abstract: Fusion protein comprising a protein to be fused, e.g. a therapeutic protein fused to the C-terminal of osteogenic growth peptide (OGP). The fusion proteins have a prolonged circulation time.
    Type: Application
    Filed: April 14, 2005
    Publication date: March 13, 2008
    Applicant: NOVO NORDISK A/S
    Inventors: Niels Blume, Jing Su, Kjeld Madsen, Nils Johansen, Lars Iversen
  • Novel Glp-1 Derivatives
    Publication number: 20070203058
    Abstract: Novel polypeptide derivatives having protracted profile of action. The present invention relates to a compound which comprises a therapeutic polypeptide linked to an albumin binding residue via a hydrophilic spacer. The present invention also relates to a compound which comprises a therapeutic polypeptide linked to an albumin binding residue via a hydrophilic spacer that separates the polypeptide and the albumin binding residue with a chemical moiety comprising at least 5 non-hydrogen atoms where 30-50% of these atoms are either N or O.
    Type: Application
    Filed: September 17, 2004
    Publication date: August 30, 2007
    Applicant: NOVO NORDISK A/S
    Inventors: Jesper Lau, Thomas Hansen, Kjeld Madsen, Paw Bloch, Florencio Dorwald, Nils Johansen
  • Conjugation of peptides
    Publication number: 20070111926
    Abstract: Methods for the selective conjugation of peptides which comprises an enzymatic incorporation of a functional group at the C-terminal end of a peptide followed by reaction with a second compound comprising the moiety to be conjugated to the peptide, wherein said second compound comprises a functional group which selectively reacts with the incorporated functional group.
    Type: Application
    Filed: March 31, 2006
    Publication date: May 17, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Magali Zundel, Bernd Peschke, Florencio Dorwald, Niels Fiil, Nils Johansen, Henning Stennicke
  • Transglutaminase mediated conjugation of peptides
    Publication number: 20070105770
    Abstract: Methods for conjugating peptides are provided comprising i) reacting a peptide with a first compound comprising a functional group in the presence of a transglutaminase capable of incorporating said compound into the peptide to form a transaminated peptide, and ii) reacting said transaminated peptide with e.g. a functionalized polymer capable of reacting with the functional group incorporated in the peptide in the enzymatic reaction.
    Type: Application
    Filed: July 11, 2006
    Publication date: May 10, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Nils Johansen, Magali Zundel, Florencio Dorwald
  • Novel GLP-1 compounds
    Publication number: 20070042956
    Abstract: Novel GLP-1 compounds and their therapeutic use.
    Type: Application
    Filed: June 16, 2006
    Publication date: February 22, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Nils Johansen, Jesper Lau, Kjeld Madsen, Thomas Hansen, Jeppe Sturis
  • Novel Melanocortin Receptor Agonists
    Publication number: 20070027091
    Abstract: Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.
    Type: Application
    Filed: March 30, 2006
    Publication date: February 1, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Kilian Conde-Frieboes, Ulrich Sensfuss, Kjeld Madsen, Nils Johansen, Leif Christensen, Thomas Hansen, Birgitte Wulff
  • Hybird molecules having factor VII/VIIa activity
    Publication number: 20060258851
    Abstract: The present invention relates to novel human coagulation Factor VII/VIIa proteins having coagulant potential/activity as well as pharmaceutical compositions comprising the polypeptides, uses and methods of treatment. In particular, the present invention relates to novel, semi synthetic analogues of human coagulation Factor VII and VIIa (FVII and FVIIa) as well as to a method of their production.
    Type: Application
    Filed: March 30, 2006
    Publication date: November 16, 2006
    Applicant: Novo Nordisk HealthCare A/G
    Inventor: Nils Johansen
  • GLP-2 derivatives
    Publication number: 20060105948
    Abstract: The present invention relates to novel derivatives of human glucagon-like peptide-2 (GLP-2) peptides, which have a protracted profile of action, as well as pharmaceutical compositions, uses and methods of treatment.
    Type: Application
    Filed: September 22, 2005
    Publication date: May 18, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Janos Kodra, Nils Johansen, Lars Thim, Bernd Peschke