Patents by Inventor Nils Nilsson
Nils Nilsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9309267Abstract: The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form.Type: GrantFiled: January 7, 2014Date of Patent: April 12, 2016Assignee: AstraZeneca ABInventors: Seth Björk, Peter Johnström, Nils A. Nilsson, Katinka Ruda, Per M. Schou, Britt-Marie Swahn, Vern Delisser
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Publication number: 20140296534Abstract: The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form.Type: ApplicationFiled: January 7, 2014Publication date: October 2, 2014Applicant: AstraZeneca ABInventors: Seth Björk, Peter Johnström, Nils A. Nilsson, Katinka Ruda, Per M. Schou, Britt-Marie Swahn, Vern Delisser
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Publication number: 20050222395Abstract: The invention relates to new competitive inhibitors of trypsin-like serine proteases, their synthesis, pharmaceutical compositions containing the compounds as active ingredients, and the use of the compounds as thrombin inhibitors, anticoagulants and antiinflammatory inhibitors for prophylaxis and treatment of related diseases, according to the formula wherein A1 represents a structural fragment of formulas A2 represent a structural fragment of formulas B represents a structural fragment of formulas Further described is novel compounds, the new use of compounds and especially new structural fragment in synthesis of pharmaceutical compounds.Type: ApplicationFiled: March 25, 2005Publication date: October 6, 2005Applicant: Astrazeneca ABInventors: Karl Antonsson, Ruth Bylund, Nils Gustafsson, Nils Nilsson
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Patent number: 5725247Abstract: Frame members for load-bearing vehicles are disclosed including upper and lower supports connected by a connecting portion and in which the end of the frame has a decreasing height towards the end thereof and an attachment plate for maintaining the relative positions of the upper and lower portions of the end of the frame. Methods for providing these frames are also disclosed.Type: GrantFiled: May 30, 1996Date of Patent: March 10, 1998Assignee: AB VolvoInventors: Nils Nilsson, Goran Levin
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Patent number: 5590733Abstract: A shock absorber and suspension apparatus are disclosed for supporting a tiltable vehicle cab on a chassis including a first shock absorber and corresponding spring attached in parallel to each other and releasably coupled between the vehicle cab and the chassis, a first coupler attached to the vehicle cab, a second coupler attached to both the first shock absorber and the spring, the first shock absorber including an attachment for attaching the upper portion of the first shock absorber to the second coupler, the attachment including a damper for damping motion of the vehicle cab, the spring including a carrier for bearing the static load acting on the shock absorber and suspension apparatus separately from the first shock absorber, and a second shock absorber connecting the second coupler to the chassis and arranged substantially transverse to the first shock absorber.Type: GrantFiled: October 5, 1994Date of Patent: January 7, 1997Assignee: AB VolvoInventors: Bengt Ljungholm, Nils Nilsson, Staffan Wendeberg, Anders K arrberg, Mikael Schill
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Patent number: 5398774Abstract: An end stop arrangement for a cabin of a vehicle supported on a frame of the vehicle and movable between upper and lower end positions, wherein the frame has at least a lower abutment surface. The end stop arrangement includes a link arm having an upper abutment surface as well as first and second ends. The link arm is pivotally connected at the first end to the cabin and at the second end to the frame. A stop arm is connected to the cabin and extends in the direction of the frame. Damping elements are connected to the stop arm. The damping elements engage the lower abutment surface when the cabin is in the lower end position and the damping elements engage the upper abutment surface when the cabin is in the upper end position.Type: GrantFiled: November 2, 1993Date of Patent: March 21, 1995Assignee: AB VolvoInventors: Nils Nilsson, Bengt Ljungholm
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Patent number: 4894221Abstract: Novel morpholino compounds having the general formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R.sub.2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, the sum of the carbon atoms in the groups R.sub.1 and R.sub.2 being at least 10 and preferably 10 to 20; and pharmaceutically acceptable salts thereof. Compositions for the treatment of the oral cavity and especially the tooth surfaces containing the novel compound or a salt thereof, preferably from 0.1 to 5% by weight thereof. Use of the compounds to inhibit the formation of dental plaque or remove plaque already formed by application of the compound in an aqueous solution or a composition to the surfaces of the oral cavity, especially the surfaces of the teeth. Processes for the preparation of the compounds.Type: GrantFiled: March 30, 1983Date of Patent: January 16, 1990Assignee: AB FerrosanInventors: Sven E. H. Hernestam, Nils A. Nilsson, Willard Lars-Olof
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Patent number: 4636382Abstract: Novel morpholino compounds having the general formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R.sub.2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, the sum of the carbon atoms in the groups R.sub.1 and R.sub.2 being at least 10 and preferably 10 to 20; and pharmaceutically acceptable salts thereof. Compositions for the treatment of the oral cavity and especially the tooth surfaces containing the novel compound or a salt thereof, preferably from 0.1 to 5% by weight thereof. Use of the compounds to inhibit the formation of dental plaque or remove plaque already formed by application of the compound in an aqueous solution or a composition to the surfaces of the oral cavity, especially the surfaces of the teeth. Processes for the preparation of the compounds.Type: GrantFiled: February 14, 1985Date of Patent: January 13, 1987Assignee: AB FerrosanInventors: Sven E. H. Hernestam, Nils A. Nilsson, Lars-Olof Willard
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Patent number: 4466676Abstract: Arrangement for cabinet with a door which can be opened at either of two opposing edges. At each of the opposing edges the door is hingedly connected with a side flap which when opened permits access to material stored in the cabinet. Each side flap is capable of being locked to the cabinet by means of two locking devices. When an arbitrary pair of locking devices is unlocked the door together with one side flap can be swung outwards from the cabinet.Type: GrantFiled: May 2, 1983Date of Patent: August 21, 1984Assignee: Forenade FabriksverkenInventor: Nils A. Nilsson
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Patent number: 4144320Abstract: Aminoalcohol compounds and acid addition salts thereof, useful in the prevention and treatment of dental caries and periodontitis, are disclosed. Methods of preparing said derivatives, orally acceptable compositions containing said compounds, and a method of treatment therewith are also disclosed.Type: GrantFiled: April 12, 1977Date of Patent: March 13, 1979Assignee: AB FerrosanInventors: Sven E. H. Hernestam, Nils A. Nilsson, Lars-Olof Willard
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Patent number: 3955652Abstract: An operating system for trailer brakes, where the pull and pressure on the coupling unit between the tractor and trailer vehicles are utilized to control the braking power of the trailer by sensing the pull and pressure on the coupling unit and regulating the supply of braking power via an amplifier.Type: GrantFiled: December 30, 1974Date of Patent: May 11, 1976Assignee: AB Linde InternationalInventors: Sture Nils Nilsson, Rune Sven Nilsson, Ingmar Karl Linus Andren